Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EL092_RS03040 Genome accession   NZ_LR134291
Coordinates   653858..654490 (+) Length   210 a.a.
NCBI ID   WP_041789571.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC7868     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 648858..659490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL092_RS03020 (NCTC7868_00598) - 649396..650136 (+) 741 WP_012000093.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EL092_RS03025 (NCTC7868_00599) stkP 650133..651986 (+) 1854 WP_012000094.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EL092_RS03030 (NCTC7868_00600) liaF 652160..652858 (+) 699 WP_012000095.1 cell wall-active antibiotics response protein LiaF -
  EL092_RS03035 (NCTC7868_00601) - 652855..653856 (+) 1002 WP_041789569.1 sensor histidine kinase -
  EL092_RS03040 (NCTC7868_00602) vraR 653858..654490 (+) 633 WP_041789571.1 response regulator transcription factor Regulator
  EL092_RS03045 (NCTC7868_00603) - 654578..655981 (+) 1404 WP_012000098.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL092_RS03050 (NCTC7868_00604) - 655978..656364 (+) 387 WP_012000099.1 S1 RNA-binding domain-containing protein -
  EL092_RS03055 (NCTC7868_00605) cysK 656401..657330 (-) 930 WP_012000100.1 cysteine synthase A -
  EL092_RS03060 (NCTC7868_00606) - 657428..658060 (-) 633 WP_041789573.1 YigZ family protein -
  EL092_RS03065 (NCTC7868_00607) comFA/cflA 658116..659417 (+) 1302 WP_012000102.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23807.35 Da        Isoelectric Point: 4.7336

>NTDB_id=1000180 EL092_RS03040 WP_041789571.1 653858..654490(+) (vraR) [Streptococcus gordonii strain NCTC7868]
MKILLVDDHEMVRLGLKSYLDLQEDVEVVAESSNGREGVELALELRPDVIIMDIVMPEMNGIEATMAILETWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADEILYAVRKVARGEVAIETEVSKKVQHHRNHIELHDDLTARERDILGLLAKGY
ENQRIADELYISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=1000180 EL092_RS03040 WP_041789571.1 653858..654490(+) (vraR) [Streptococcus gordonii strain NCTC7868]
ATGAAAATTTTATTAGTAGATGATCACGAAATGGTTCGCTTGGGCTTAAAAAGCTACTTGGACTTACAAGAAGATGTTGA
AGTGGTGGCAGAAAGTTCTAATGGCCGTGAGGGAGTTGAGCTGGCTTTGGAGCTAAGACCAGATGTCATCATCATGGATA
TTGTTATGCCAGAGATGAATGGTATCGAGGCGACTATGGCCATTCTAGAAACTTGGCCAGAAGCAAAAATTTTGATTTTG
ACTTCCTACTTGGATAATGAAAAGATTTATCCTGTTTTGGATGCTGGAGCTAAAGGATACATGCTGAAGACATCTAGTGC
AGATGAGATTTTATATGCTGTCCGAAAAGTAGCTAGAGGAGAAGTTGCGATTGAAACAGAAGTCAGTAAAAAAGTTCAGC
ACCATCGCAATCACATTGAATTGCATGATGATTTAACCGCCCGAGAACGAGATATTTTGGGGCTTCTAGCCAAGGGCTAT
GAAAATCAACGCATTGCTGATGAGCTTTATATTTCTCTGAAAACAGTAAAAACTCATGTTTCTAATATCTTGTCAAAATT
GGAAGTGAGTGACCGGACTCAAGCGGTTGTTTATGCCTTTCAGCATCACTTAGTTCCTCAGGAAGACTTCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

98.095

0.533
  degU Bacillus subtilis subsp. subtilis str. 168

40.179

100

0.429

Multiple sequence alignment