Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1922975..1923491 Replicon chromosome
Accession NC_004603
Organism Vibrio parahaemolyticus RIMD 2210633

Toxin (Protein)


Gene name relB Uniprot ID U2ZZV8
Locus tag VP_RS08780 Protein ID WP_005464459.1
Coordinates 1922975..1923244 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W4CB60
Locus tag VP_RS08785 Protein ID WP_005483180.1
Coordinates 1923237..1923491 (-) Length 85 a.a.

Genomic Context

VP_RS08725VP_RS08730VP_RS08735VP_RS08740VP_RS08745VP_RS08750VP_RS08755VP_RS08760VP_RS08765VP_RS08770VP_RS08775VP_RS08780VP_RS08785VP_RS08790VP_RS08795VP_RS08800VP_RS08805VP_RS08810VP_RS08815VP_RS08820VP_RS23585VP_RS08830VP_RS23705VP_RS08840
Location: 1918881..1919270 (390 bp)
Type: Others
Protein ID: WP_005490691.1
Location: 1919308..1919400 (93 bp)
Type: Others
Protein ID: WP_072833112.1
Location: 1919390..1919866 (477 bp)
Type: Others
Protein ID: WP_017449567.1
Location: 1919988..1920119 (132 bp)
Type: Others
Protein ID: WP_078532947.1
Location: 1920199..1920405 (207 bp)
Type: Others
Protein ID: WP_005462168.1
Location: 1920608..1920700 (93 bp)
Type: Others
Protein ID: WP_017045846.1
Location: 1920735..1921136 (402 bp)
Type: Others
Protein ID: WP_005483261.1
Location: 1921169..1921285 (117 bp)
Type: Others
Protein ID: WP_161609362.1
Location: 1921289..1921735 (447 bp)
Type: Others
Protein ID: WP_024699215.1
Location: 1922313..1922402 (90 bp)
Type: Others
Protein ID: WP_072833196.1
Location: 1922430..1922810 (381 bp)
Type: Others
Protein ID: WP_005467118.1
Location: 1922975..1923244 (270 bp)
Type: Toxin
Protein ID: WP_005464459.1
Location: 1923237..1923491 (255 bp)
Type: Antitoxin
Protein ID: WP_005483180.1
Location: 1923594..1923686 (93 bp)
Type: Others
Protein ID: WP_011105955.1
Location: 1923710..1924879 (1170 bp)
Type: Others
Protein ID: WP_005483289.1
Location: 1924843..1924935 (93 bp)
Type: Others
Protein ID: WP_072833197.1
Location: 1924950..1925483 (534 bp)
Type: Others
Protein ID: WP_005483198.1
Location: 1925581..1925673 (93 bp)
Type: Others
Protein ID: WP_005464677.1
Location: 1925696..1926466 (771 bp)
Type: Others
Protein ID: WP_005464405.1
Location: 1926537..1927358 (822 bp)
Type: Others
Protein ID: WP_005464673.1
Location: 1927333..1927473 (141 bp)
Type: Others
Protein ID: WP_162828790.1
Location: 1927502..1928044 (543 bp)
Type: Others
Protein ID: WP_005464345.1
Location: 1928077..1928166 (90 bp)
Type: Others
Protein ID: WP_072833190.1
Location: 1928198..1928470 (273 bp)
Type: Others
Protein ID: WP_005462157.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
VP_RS08725 (VP1813)1918881..1919270-390WP_005490691.1hypothetical protein-
VP_RS087301919308..1919400-93WP_072833112.1DUF3265 domain-containing protein-
VP_RS08735 (VP1814)1919390..1919866-477WP_017449567.1hypothetical protein-
VP_RS087401919988..1920119-132WP_078532947.1DUF3265 domain-containing protein-
VP_RS087451920199..1920405-207WP_005462168.1hypothetical protein-
VP_RS087501920608..1920700-93WP_017045846.1DUF3265 domain-containing protein-
VP_RS08755 (VP1816)1920735..1921136-402WP_005483261.1HIT family protein-
VP_RS087601921169..1921285-117WP_161609362.1DUF3265 domain-containing protein-
VP_RS08765 (VP1817)1921289..1921735-447WP_024699215.1hypothetical protein-
VP_RS087701922313..1922402-90WP_072833196.1DUF3265 domain-containing protein-
VP_RS08775 (VP1819)1922430..1922810-381WP_005467118.1energy transducer TonB-
VP_RS08780 (VP1820)1922975..1923244-270WP_005464459.1Txe/YoeB family addiction module toxinToxin
VP_RS08785 (VP1821)1923237..1923491-255WP_005483180.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
VP_RS08790 (VP1822)1923594..1923686-93WP_011105955.1DUF3265 domain-containing protein-
VP_RS08795 (VP1823)1923710..1924879-1170WP_005483289.1hypothetical protein-
VP_RS088001924843..1924935-93WP_072833197.1DUF3265 domain-containing protein-
VP_RS08805 (VP1824)1924950..1925483-534WP_005483198.1hypothetical protein-
VP_RS088101925581..1925673-93WP_005464677.1DUF3265 domain-containing protein-
VP_RS08815 (VP1825)1925696..1926466-771WP_005464405.1CBS domain-containing protein-
VP_RS08820 (VP1826)1926537..1927358-822WP_005464673.1DUF1669 domain-containing protein-
VP_RS235851927333..1927473-141WP_162828790.1hypothetical protein-
VP_RS08830 (VP1827)1927502..1928044-543WP_005464345.1GNAT family N-acetyltransferase-
VP_RS237051928077..1928166-90WP_072833190.1DUF3265 domain-containing protein-
VP_RS08840 (VP1828)1928198..1928470-273WP_005462157.1nicotinamide mononucleotide transporter-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideIntegron--1901751..194924347492


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10614.96 Da        Isoelectric Point: 7.9816

>T20884 WP_005464459.1 NC_004603:c1923244-1922975 [Vibrio parahaemolyticus RIMD 2210633]
MSSSQRLLSWTDDAWDDYLYWQTQDKKTLKRINKLINDVKRSPFEGIGKPEPLKENLSGFWSRRIDDTNRLVYAVDDQAI
TIISCRYHY

Download         Length: 270 bp

>T20884 NC_004603:c1923244-1922975 [Vibrio parahaemolyticus RIMD 2210633]
ATGAGTAGTAGTCAACGTTTATTATCGTGGACTGATGATGCTTGGGATGACTACCTGTATTGGCAAACTCAAGACAAGAA
AACACTCAAGCGCATCAATAAACTCATCAATGATGTTAAGCGCTCTCCATTTGAGGGCATTGGTAAACCAGAGCCGTTAA
AAGAGAACTTATCTGGTTTTTGGTCTCGTCGTATTGATGATACTAATAGGCTTGTTTACGCAGTCGATGATCAAGCGATA
ACGATAATTTCATGTCGTTACCACTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9481.66 Da        Isoelectric Point: 5.0623

>AT20884 WP_005483180.1 NC_004603:c1923491-1923237 [Vibrio parahaemolyticus RIMD 2210633]
MRIVSFTEARNGLKAVLDGVVNDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPQNVEHLNRSIAQYRAGKTTARE
LIDE

Download         Length: 255 bp

>AT20884 NC_004603:c1923491-1923237 [Vibrio parahaemolyticus RIMD 2210633]
ATGAGAATCGTATCTTTTACTGAAGCTAGAAATGGTCTCAAAGCTGTTTTAGACGGTGTAGTTAATGATGCTGATACAAC
AGTTATTACACGCCGTGATTCTGAGGATGCAGTGGTTATGTCTTTAGACTACTACAATAGCCTTATGGAGACTGTTCATT
TACTACGCTCTCCTCAAAACGTTGAACACCTAAACCGTTCGATAGCACAGTACCGCGCTGGTAAAACAACAGCACGAGAG
TTAATTGATGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBU2ZZV8

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A7W4CB60

References