Detailed information of regulator


Summary

Regulator ID REG0368 experimental
Regulator type protein
Regulatory pathway (from literatures) Global regulator
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00004 experimental (Type i1)
Strain Pseudomonas aeruginosa PAO1
Replicon chromosome
Sequence Protein sequence (245 a.a.); Nucleotide sequence (735 bp)
Description Anr regulates the expression of H2-T6SS genes and ModA secretion under anaerobic conditions.
Reference
External database links

Locus tag (Gene) PA1544 (Anr)
Coordinates (Strand) 1681071..1681805 (-)
NCBI ID 15596741
RefSeq NC_002516
Uniprot ID ANR_PSEAE
KEGG ID pae:PA1544
KEGG pathway (determined by BlastKOALA) -
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
H2-T6SS transcriptional level and ModA secretion ↓ -
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
Crp PF00325.22 1.6e-17 188..219
cNMP_binding PF00027.31 2.5e-16 45..129
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-244 MAETIKVRALPQAHCKDCSLAPLCLPLSLTVEDMDSLDEIVKRGRPLKKGEFLFRQGDPFGSVFAVRSGALKTFSITDAGEEQITGFHLPSELVGLSGMDTETYPVSAQALETTSVCEIPFERLDELSEQLPQLRRQLMRLMSREIRDDQQMMLLLSKKTADERIATFLVNLSARFRARGFSAQQFRLAMSRNEIGNYLGLAVETVSRVFTRFQQNGLISAEGKEVHILDSIELCALAGGQLEG


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9839 - -


  Protein sequence of regulator: 245 a.a.    .

>REG0368 NC_002516:c1681805-1681071 [Pseudomonas aeruginosa PAO1]
MAETIKVRALPQAHCKDCSLAPLCLPLSLTVEDMDSLDEIVKRGRPLKKGEFLFRQGDPFGSVFAVRSGALKTFSITDAG
EEQITGFHLPSELVGLSGMDTETYPVSAQALETTSVCEIPFERLDELSEQLPQLRRQLMRLMSREIRDDQQMMLLLSKKT
ADERIATFLVNLSARFRARGFSAQQFRLAMSRNEIGNYLGLAVETVSRVFTRFQQNGLISAEGKEVHILDSIELCALAGG
QLEG*

  Nucleotide sequence of regulator: 735 bp    .

>REG0368 NC_002516:c1681805-1681071 [Pseudomonas aeruginosa PAO1]
ATGGCCGAAACCATCAAGGTGCGCGCACTGCCCCAAGCACACTGCAAGGATTGCAGTCTGGCCCCGCTGTGCCTCCCCCT
GTCGCTGACCGTGGAAGACATGGATTCGCTGGACGAGATCGTCAAGCGCGGTCGTCCCCTGAAGAAAGGCGAATTCCTGT
TCCGCCAGGGTGATCCTTTCGGCTCGGTCTTTGCCGTGCGCTCCGGCGCCCTGAAAACCTTCAGCATCACCGATGCCGGC
GAAGAGCAGATCACCGGCTTCCACCTGCCCAGCGAGCTGGTCGGCCTGTCCGGGATGGATACCGAGACCTATCCGGTATC
CGCCCAGGCCCTGGAAACCACCTCGGTCTGCGAGATTCCCTTCGAGCGCCTGGACGAACTGTCCGAGCAGCTGCCGCAGC
TGCGCCGTCAACTGATGCGTCTGATGAGCCGGGAAATCCGCGATGACCAGCAGATGATGCTGCTGCTGTCGAAGAAGACT
GCCGACGAGCGCATCGCCACCTTCCTGGTCAACCTGTCGGCGCGCTTCCGTGCCCGTGGCTTCTCCGCCCAGCAGTTCCG
CCTGGCCATGTCGCGCAACGAGATCGGCAACTATCTCGGCCTGGCCGTGGAAACCGTGTCGCGGGTCTTCACCCGCTTCC
AGCAGAACGGCCTGATCAGCGCGGAAGGCAAGGAAGTGCACATCCTCGACTCCATCGAGCTGTGCGCCCTCGCCGGCGGC
CAGCTGGAAGGCTGA