Detailed information of regulator
Summary
| Regulator ID | REG0246  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | QS regulatory pathway |
| KEGG pathway (determined by BlastKOALA) | - |
| Related T6SS | T6SS00372 (Type i4b) |
| Strain | Edwardsiella tarda EIB202 |
| Replicon | chromosome |
| Sequence | Protein sequence (224 a.a.); Nucleotide sequence (672 bp) |
| Description | FabR activates T3/T6SS production through esrB in E. piscicida |
| Reference |
External database links
| Locus tag (Gene) | ETAE_3474 (fabR) |
| Coordinates (Strand) | 3666488..3667159 (-) |
| NCBI ID | 502613311 |
| RefSeq | NC_013508 |
| Uniprot ID | D0ZHB2_EDWTE, A0A0H3DX53_EDWTF |
| KEGG ID | etd:ETAF_3136, etr:ETAE_3474 |
| KEGG pathway (determined by BlastKOALA) | - |
| PDB ID | - |
Target
| Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| Unknown | ↓ | - |
Pfam domain hit(s) of regulator
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| TetR_N | PF00440.25 | 1.8e-07 | 16..58 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-223 | MGVRAQQKERTRRSLIEAAFNQLSAERSFASLSLREVSREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVATFMEFIGNNPNAFRLLLRERSGTSAAFRAAVQREIQHFIAELADYLEIENHMPRSFTEAQAEAMVTIVFSAGAEALDIDSEQRRQLEERLVLQLRMISKGVYYWYRREQEKAHLAQVAASAIDGGHHQKS |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9463 | - | - |
Protein sequence of regulator: 224 a.a. .
>REG0246 NC_013508:c3667159-3666488 [Edwardsiella tarda EIB202]
MGVRAQQKERTRRSLIEAAFNQLSAERSFASLSLREVSREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQR
IAKGGSVIRTSVATFMEFIGNNPNAFRLLLRERSGTSAAFRAAVQREIQHFIAELADYLEIENHMPRSFTEAQAEAMVTI
VFSAGAEALDIDSEQRRQLEERLVLQLRMISKGVYYWYRREQEKAHLAQVAASAIDGGHHQKS*
MGVRAQQKERTRRSLIEAAFNQLSAERSFASLSLREVSREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQR
IAKGGSVIRTSVATFMEFIGNNPNAFRLLLRERSGTSAAFRAAVQREIQHFIAELADYLEIENHMPRSFTEAQAEAMVTI
VFSAGAEALDIDSEQRRQLEERLVLQLRMISKGVYYWYRREQEKAHLAQVAASAIDGGHHQKS*
Nucleotide sequence of regulator: 672 bp .
>REG0246 NC_013508:c3667159-3666488 [Edwardsiella tarda EIB202]
ATGGGCGTCAGGGCACAGCAAAAGGAACGGACTCGCCGTTCACTGATTGAGGCGGCATTTAATCAGCTCAGCGCCGAGCG
CAGCTTCGCCAGCCTGAGCCTGCGAGAGGTTTCGCGCGAGGCGGGGATCGCGCCCACGTCGTTTTATCGCCATTTTCGCG
ATGTGGATGAGCTGGGGCTCACCATGGTGGACGAAAGCGGCCTGATGCTGCGTCAGCTGATGCGTCAGGCGCGCCAGCGT
ATCGCGAAGGGCGGTAGCGTGATCCGTACCTCGGTCGCGACCTTCATGGAGTTTATTGGTAATAATCCCAATGCGTTTCG
TTTGCTGCTGCGTGAGCGTTCGGGCACCTCGGCGGCCTTTCGCGCCGCGGTACAGCGTGAAATTCAGCATTTTATTGCGG
AACTTGCCGACTATCTGGAAATCGAAAATCACATGCCGCGCAGTTTTACAGAAGCGCAGGCCGAGGCGATGGTCACCATT
GTGTTCAGCGCGGGCGCCGAGGCGTTGGATATCGACAGTGAGCAACGCCGTCAGCTAGAGGAGCGCCTGGTGCTGCAGCT
GCGGATGATTTCCAAAGGCGTGTACTACTGGTATCGTCGCGAACAGGAGAAAGCGCACCTTGCGCAGGTCGCCGCGTCGG
CCATCGACGGCGGACACCATCAAAAGTCATAG
ATGGGCGTCAGGGCACAGCAAAAGGAACGGACTCGCCGTTCACTGATTGAGGCGGCATTTAATCAGCTCAGCGCCGAGCG
CAGCTTCGCCAGCCTGAGCCTGCGAGAGGTTTCGCGCGAGGCGGGGATCGCGCCCACGTCGTTTTATCGCCATTTTCGCG
ATGTGGATGAGCTGGGGCTCACCATGGTGGACGAAAGCGGCCTGATGCTGCGTCAGCTGATGCGTCAGGCGCGCCAGCGT
ATCGCGAAGGGCGGTAGCGTGATCCGTACCTCGGTCGCGACCTTCATGGAGTTTATTGGTAATAATCCCAATGCGTTTCG
TTTGCTGCTGCGTGAGCGTTCGGGCACCTCGGCGGCCTTTCGCGCCGCGGTACAGCGTGAAATTCAGCATTTTATTGCGG
AACTTGCCGACTATCTGGAAATCGAAAATCACATGCCGCGCAGTTTTACAGAAGCGCAGGCCGAGGCGATGGTCACCATT
GTGTTCAGCGCGGGCGCCGAGGCGTTGGATATCGACAGTGAGCAACGCCGTCAGCTAGAGGAGCGCCTGGTGCTGCAGCT
GCGGATGATTTCCAAAGGCGTGTACTACTGGTATCGTCGCGAACAGGAGAAAGCGCACCTTGCGCAGGTCGCCGCGTCGG
CCATCGACGGCGGACACCATCAAAAGTCATAG