Detailed information of regulator


Summary

Regulator ID REG0201 experimental
Regulator type protein
Regulatory pathway (from literatures) Global regulator
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00272 experimental (Type i1)
Strain Proteus mirabilis HI4320
Replicon chromosome
Sequence Protein sequence (108 a.a.); Nucleotide sequence (324 bp)
Description MrpJ directly binds and regulates parts of T6SS genes promotor.;
Reference

External database links

Locus tag (Gene) PMI0271 (MrpJ)
Coordinates (Strand) 318458..318781 (+)
NCBI ID 490365253
RefSeq NC_010554
Uniprot ID Q9R6Q7_PROMI
KEGG ID -
KEGG pathway (determined by BlastKOALA) -
PDB ID -

  Target
Target Regulation (↓/↑) Target sequence
PMI0749 (tssA) ACAAATATAATGAGTA/ACTCTAATAATGAGTA
The binding motif of ChIP-enriched MrpJ gene targets
PMI2990 (idsA/hcp) ACACTCAATATGCGTA/ACACTTTTTATGACTG
The binding motif of ChIP-enriched MrpJ gene targets

Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
HTH_3 PF01381.24 1.4e-12 20..74

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-107 MMMNFDFANIDVNASVGKKIQKKRKELGYTGMQLAKKIGVSQQQFSRYERGMNKIDLRHLVLLALYLNTPIYWFFEDCYVKKPSLNNKGIDKRNYVIAQATPDAFHY



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9854 - -



  Protein sequence of regulator: 108 a.a.    .

>REG0201 NC_010554:318458-318781 [Proteus mirabilis HI4320]
MMMNFDFANIDVNASVGKKIQKKRKELGYTGMQLAKKIGVSQQQFSRYERGMNKIDLRHLVLLALYLNTPIYWFFEDCYV
KKPSLNNKGIDKRNYVIAQATPDAFHY*

  Nucleotide sequence of regulator: 324 bp    .

>REG0201 NC_010554:318458-318781 [Proteus mirabilis HI4320]
ATGATGATGAATTTTGATTTTGCGAATATAGATGTAAATGCTTCTGTAGGTAAAAAGATCCAAAAAAAACGTAAAGAGCT
GGGTTATACCGGTATGCAGCTGGCTAAAAAAATTGGTGTCAGCCAGCAACAGTTTTCTCGCTATGAACGAGGTATGAACA
AAATAGATCTCAGACATTTAGTGTTGTTAGCTCTCTATTTAAATACACCCATTTATTGGTTTTTTGAGGATTGCTACGTA
AAAAAGCCTTCATTAAATAATAAAGGAATAGATAAGCGCAATTATGTTATTGCTCAAGCAACACCTGATGCTTTTCATTA
TTGA