Detailed information of regulator
Summary
Regulator ID | REG0153 |
Regulator type | protein |
Regulatory pathway (from literatures) | Global regulator |
KEGG pathway (determined by BlastKOALA) | Biofilm formation - Escherichia coli (map02026) |
Related T6SS | T6SS00114 (Type i3) |
Strain | Burkholderia thailandensis E264 |
Replicon | chromosome |
Sequence | Protein sequence (320 a.a.); Nucleotide sequence (960 bp) |
Description | OxyR in chromosome I negatively regulates the expression of T6SS-4 in chromosome II by specifically recognizing an operator within the T6SS-4 promoter. |
Reference |
External database links
Locus tag (Gene) | BTH_I1281 (OxyR) |
Coordinates (Strand) | 1432632..1433591 (+) |
NCBI ID | 497575020 |
RefSeq | NC_007651 |
Uniprot ID | Q2SZ21_BURTA |
KEGG ID | bte:BTH_I1281 |
KEGG pathway (determined by BlastKOALA) | map02026 |
PDB ID | - |
Target
Target | Regulation (↓/↑) | Target sequence |
---|---|---|
BTH_RS09735 (T6SS-4) Promotor,−536 to −186 relative to the ATG start codon | ↑ | cggcgtccgggaaaatattccacggaaaccgtttacgctgctgtttttttctcagtggtattaacccaccccttccgcccagcccgatccctgcgagtcggcatacgccggcttccgcaacggcaatcggtaagatgcactcccgctaaatcaaataccgcacgcgcataaatcgatgcgccgtcgcgatcgcggcggaaataacatccaagcaccgggtttatctgaagcgtcacaccttagtggccctcaacgacaacggcgtgacaatcgttcatatcgttacagtctacgctgtaaacttatagaacgctcgtaaatttggcaagcggaaataattttttcttacaaac |
Pfam domain hit(s) of regulator
Domain | Pfam ID | E-value | Aligned region |
---|---|---|---|
LysR_substrate | PF03466.22 | 3.2e-46 | 90..301 |
HTH_1 | PF00126.29 | 3e-17 | 4..61 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
Prediction | Region | Sequence |
---|---|---|
Outside | 1-319 | MTLTELKYIVAVARERHFGRAAEACFVSQPTLSVAIKKLEDELNVQIFERGASEVSVTPIGDQIVTQAQRVLEQTFAIKEIAKQGKDPLIGPFRLGVIYTIGPYLLPTLVKQMIRRVPQMPLMLQENYTLKLLELLKQGEIDAAIMALPFPETGLMVRPLYDEPFVVALPTGHPWGTRRKIDAADLKQETMLLLGNGHCFRDHVLGVCPELMHFSQTADGIQKTFEGSSLETIRHMVASGVGITVLPRMSVAEVGPHASGPDADLLSYVPFEDPVPDRRVVLVWRKSFTRMPAIDAISEAIAACELPGVAKLDIPATVN |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction | Probability | Cleavage site | Signal peptide sequence |
---|---|---|---|
Other | 0.9792 | - | - |
Protein sequence of regulator: 320 a.a. .
>REG0153 NC_007651:1432632-1433591 [Burkholderia thailandensis E264]
MTLTELKYIVAVARERHFGRAAEACFVSQPTLSVAIKKLEDELNVQIFERGASEVSVTPIGDQIVTQAQRVLEQTFAIKE
IAKQGKDPLIGPFRLGVIYTIGPYLLPTLVKQMIRRVPQMPLMLQENYTLKLLELLKQGEIDAAIMALPFPETGLMVRPL
YDEPFVVALPTGHPWGTRRKIDAADLKQETMLLLGNGHCFRDHVLGVCPELMHFSQTADGIQKTFEGSSLETIRHMVASG
VGITVLPRMSVAEVGPHASGPDADLLSYVPFEDPVPDRRVVLVWRKSFTRMPAIDAISEAIAACELPGVAKLDIPATVN*
MTLTELKYIVAVARERHFGRAAEACFVSQPTLSVAIKKLEDELNVQIFERGASEVSVTPIGDQIVTQAQRVLEQTFAIKE
IAKQGKDPLIGPFRLGVIYTIGPYLLPTLVKQMIRRVPQMPLMLQENYTLKLLELLKQGEIDAAIMALPFPETGLMVRPL
YDEPFVVALPTGHPWGTRRKIDAADLKQETMLLLGNGHCFRDHVLGVCPELMHFSQTADGIQKTFEGSSLETIRHMVASG
VGITVLPRMSVAEVGPHASGPDADLLSYVPFEDPVPDRRVVLVWRKSFTRMPAIDAISEAIAACELPGVAKLDIPATVN*
Nucleotide sequence of regulator: 960 bp .
>REG0153 NC_007651:1432632-1433591 [Burkholderia thailandensis E264]
ATGACGCTTACTGAACTGAAGTACATCGTCGCGGTCGCGCGCGAGCGCCATTTCGGCCGGGCGGCCGAAGCCTGCTTCGT
CAGCCAGCCGACGCTGTCGGTCGCGATCAAGAAGCTGGAAGACGAGTTGAACGTGCAGATCTTCGAGCGCGGCGCGAGCG
AGGTGAGCGTGACGCCGATCGGCGACCAGATCGTCACGCAAGCGCAGCGCGTGCTCGAGCAGACGTTCGCGATCAAGGAG
ATCGCGAAGCAGGGCAAGGATCCGCTCATCGGGCCGTTTCGGCTCGGCGTGATCTATACGATCGGGCCCTATCTGCTGCC
GACGCTCGTCAAGCAGATGATTCGCCGCGTGCCGCAAATGCCGTTGATGCTGCAGGAGAACTACACGCTGAAGCTGCTCG
AGCTGCTCAAACAGGGCGAGATCGACGCGGCGATCATGGCATTGCCGTTTCCCGAAACCGGCCTGATGGTGCGGCCGCTG
TACGACGAGCCGTTCGTCGTCGCGCTGCCCACCGGGCATCCATGGGGGACGCGCCGCAAGATCGACGCGGCCGACCTGAA
GCAGGAGACGATGCTGCTGCTCGGCAACGGCCATTGCTTCCGCGACCACGTGCTCGGCGTATGTCCGGAGCTGATGCATT
TTTCGCAGACGGCGGACGGCATTCAGAAGACGTTCGAAGGCTCGTCGCTCGAGACGATCCGCCACATGGTCGCGAGCGGC
GTCGGGATCACGGTGCTGCCGCGGATGTCGGTCGCCGAGGTGGGGCCGCATGCAAGCGGACCGGACGCGGACCTGCTGTC
CTACGTGCCGTTCGAGGACCCGGTGCCGGATCGGCGCGTCGTGCTCGTGTGGCGCAAGAGCTTCACGCGGATGCCGGCGA
TCGACGCGATCAGCGAGGCGATCGCCGCATGCGAGTTGCCCGGCGTGGCGAAGCTCGACATCCCGGCTACGGTGAATTGA
ATGACGCTTACTGAACTGAAGTACATCGTCGCGGTCGCGCGCGAGCGCCATTTCGGCCGGGCGGCCGAAGCCTGCTTCGT
CAGCCAGCCGACGCTGTCGGTCGCGATCAAGAAGCTGGAAGACGAGTTGAACGTGCAGATCTTCGAGCGCGGCGCGAGCG
AGGTGAGCGTGACGCCGATCGGCGACCAGATCGTCACGCAAGCGCAGCGCGTGCTCGAGCAGACGTTCGCGATCAAGGAG
ATCGCGAAGCAGGGCAAGGATCCGCTCATCGGGCCGTTTCGGCTCGGCGTGATCTATACGATCGGGCCCTATCTGCTGCC
GACGCTCGTCAAGCAGATGATTCGCCGCGTGCCGCAAATGCCGTTGATGCTGCAGGAGAACTACACGCTGAAGCTGCTCG
AGCTGCTCAAACAGGGCGAGATCGACGCGGCGATCATGGCATTGCCGTTTCCCGAAACCGGCCTGATGGTGCGGCCGCTG
TACGACGAGCCGTTCGTCGTCGCGCTGCCCACCGGGCATCCATGGGGGACGCGCCGCAAGATCGACGCGGCCGACCTGAA
GCAGGAGACGATGCTGCTGCTCGGCAACGGCCATTGCTTCCGCGACCACGTGCTCGGCGTATGTCCGGAGCTGATGCATT
TTTCGCAGACGGCGGACGGCATTCAGAAGACGTTCGAAGGCTCGTCGCTCGAGACGATCCGCCACATGGTCGCGAGCGGC
GTCGGGATCACGGTGCTGCCGCGGATGTCGGTCGCCGAGGTGGGGCCGCATGCAAGCGGACCGGACGCGGACCTGCTGTC
CTACGTGCCGTTCGAGGACCCGGTGCCGGATCGGCGCGTCGTGCTCGTGTGGCGCAAGAGCTTCACGCGGATGCCGGCGA
TCGACGCGATCAGCGAGGCGATCGCCGCATGCGAGTTGCCCGGCGTGGCGAAGCTCGACATCCCGGCTACGGTGAATTGA