Detailed information of regulator


Summary

Regulator ID REG0126 experimental
Regulator type protein
Regulatory pathway (from literatures) Transcription regulator
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00070 experimental (Type i1)
Strain Burkholderia mallei ATCC 23344
Replicon chromosome
Sequence Protein sequence (354 a.a.); Nucleotide sequence (1062 bp)
Description virAG and BMAA1517 independently control transcription of this T6S cluster.VirAG and BMAA1517 sense specific conditions in the host environment, and in response, activate the cluster 1 T6S genes.
Reference
External database links

Locus tag (Gene) BMAA1517
Coordinates (Strand) 1646532..1647593 (-)
NCBI ID 499517952
RefSeq NC_006349
Uniprot ID A0A0H2WB87_BURMA
KEGG ID bma:BMAA1517
KEGG pathway (determined by BlastKOALA) -
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
Hcp1 (BMAA0742) expression ↓ -
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
AraC_binding_2 PF14525.8 2.4e-20 53..227
HTH_18 PF12833.9 5.3e-18 267..346
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-353 MPHAFRTDSRPTRFPSHHSPPLTMAKMHAPRGGTLLQFFSTDDMPLARAAAFWSAHVFQCEDVRASSARAFHGHGFLCRCERGRFVRFRGASLDTRIGAAWLSAAPADAYVTICALHAGECTVEAPGLPDVRFRANELFMLDGGQPMRVRWSEPCFSALRLPRASVGRTLGQAAMDASPSAASLQEARLAPFLAAELALIGGRGPTLSSDELDYMLARAAELGRTLLQAALSSRARRGAPARADRLQAAYRYIEQHLHLPTLTPERIADAIHCSRTQLYRLFRHESQTVKAALREARLNRSLGYLEQPEVTLSIGEIAHACGFPDQSTFGKLFRRRFGRTPGEVRRAARGCSI


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9645 - -


  Protein sequence of regulator: 354 a.a.    .

>REG0126 NC_006349:c1647593-1646532 [Burkholderia mallei ATCC 23344]
MPHAFRTDSRPTRFPSHHSPPLTMAKMHAPRGGTLLQFFSTDDMPLARAAAFWSAHVFQCEDVRASSARAFHGHGFLCRC
ERGRFVRFRGASLDTRIGAAWLSAAPADAYVTICALHAGECTVEAPGLPDVRFRANELFMLDGGQPMRVRWSEPCFSALR
LPRASVGRTLGQAAMDASPSAASLQEARLAPFLAAELALIGGRGPTLSSDELDYMLARAAELGRTLLQAALSSRARRGAP
ARADRLQAAYRYIEQHLHLPTLTPERIADAIHCSRTQLYRLFRHESQTVKAALREARLNRSLGYLEQPEVTLSIGEIAHA
CGFPDQSTFGKLFRRRFGRTPGEVRRAARGCSI*

  Nucleotide sequence of regulator: 1062 bp    .

>REG0126 NC_006349:c1647593-1646532 [Burkholderia mallei ATCC 23344]
ATGCCACATGCGTTCCGCACGGATTCTCGCCCAACGCGCTTCCCGTCGCACCATTCACCGCCCCTCACCATGGCGAAGAT
GCACGCGCCCCGCGGCGGCACGCTGCTGCAATTCTTTTCGACCGACGACATGCCGCTCGCGCGCGCGGCGGCGTTCTGGA
GCGCGCACGTGTTCCAGTGCGAGGACGTGCGCGCGTCGTCCGCGCGCGCGTTTCACGGGCACGGCTTTCTCTGCCGCTGC
GAGCGCGGCCGGTTCGTTCGCTTTCGCGGCGCGTCGCTCGACACGCGCATCGGCGCGGCGTGGCTGAGCGCCGCGCCAGC
CGATGCGTACGTGACGATCTGCGCGCTGCATGCGGGCGAGTGCACGGTCGAAGCGCCCGGCTTGCCGGATGTGCGCTTTC
GTGCGAACGAGCTGTTCATGCTGGACGGCGGTCAGCCGATGCGCGTGCGCTGGAGCGAGCCGTGTTTCAGCGCGCTCAGG
CTGCCGCGCGCATCGGTGGGGCGTACGCTCGGCCAGGCGGCGATGGACGCGTCGCCGAGCGCGGCTTCGTTGCAGGAGGC
GCGGCTCGCGCCGTTTCTCGCGGCGGAGCTCGCGCTGATCGGCGGTCGCGGCCCGACGCTGTCGTCGGACGAGCTCGATT
ACATGCTCGCGCGCGCAGCCGAGCTCGGCCGCACGCTGCTTCAGGCGGCGCTGTCGTCGCGCGCGCGGCGCGGCGCGCCC
GCGCGCGCCGACCGGCTGCAGGCCGCGTATCGCTACATCGAGCAGCATCTTCATCTGCCGACGCTCACACCCGAGCGGAT
CGCCGACGCGATCCATTGCTCGCGCACGCAGCTCTATCGGCTGTTCCGCCATGAATCGCAGACGGTGAAGGCGGCGCTGC
GCGAGGCGCGGCTGAACCGCAGCCTCGGCTATCTCGAGCAGCCCGAGGTTACGCTCAGCATCGGCGAGATCGCGCATGCT
TGCGGTTTTCCCGATCAGTCGACGTTCGGCAAGCTGTTTCGCCGGCGCTTCGGCAGAACGCCCGGCGAGGTGCGCCGCGC
CGCGCGGGGATGTTCGATATGA