Detailed information of regulator


Summary

Regulator ID REG0126 experimental
Regulator type protein
Regulatory pathway (from literatures) Transcription regulator
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00070 experimental (Type i1)
Strain Burkholderia mallei ATCC 23344
Replicon chromosome
Sequence Protein sequence (354 a.a.); Nucleotide sequence (1062 bp)
Description virAG and BMAA1517 independently control transcription of this T6S cluster.VirAG and BMAA1517 sense specific conditions in the host environment, and in response, activate the cluster 1 T6S genes.
Reference
External database links

Locus tag (Gene) BMAA1517
Coordinates (Strand) 1646532..1647593 (-)
NCBI ID 499517952
RefSeq NC_006349
Uniprot ID A0A0H2WB87_BURMA
KEGG ID bma:BMAA1517
KEGG pathway (determined by BlastKOALA) -
PDB ID -
  Target
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Target
Regulation (↓/↑)
Target sequence
Hcp1 (BMAA0742) expression↓-
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Pfam domain hit(s) of regulator

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Domain
Pfam ID
E-value
Aligned region
AraC_binding_2PF14525.82.4e-2053..227
HTH_18PF12833.95.3e-18267..346
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Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

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Prediction                
Region    
Sequence
Outside1-353MPHAFRTDSRPTRFPSHHSPPLTMAKMHAPRGGTLLQFFSTDDMPLARAAAFWSAHVFQCEDVRASSARAFHGHGFLCRCERGRFVRFRGASLDTRIGAAWLSAAPADAYVTICALHAGECTVEAPGLPDVRFRANELFMLDGGQPMRVRWSEPCFSALRLPRASVGRTLGQAAMDASPSAASLQEARLAPFLAAELALIGGRGPTLSSDELDYMLARAAELGRTLLQAALSSRARRGAPARADRLQAAYRYIEQHLHLPTLTPERIADAIHCSRTQLYRLFRHESQTVKAALREARLNRSLGYLEQPEVTLSIGEIAHACGFPDQSTFGKLFRRRFGRTPGEVRRAARGCSI


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
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Prediction       
Probability
Cleavage site
Signal peptide sequence
Other0.9645--


  Protein sequence of regulator: 354 a.a.    .

>REG0126 NC_006349:c1647593-1646532 [Burkholderia mallei ATCC 23344]
MPHAFRTDSRPTRFPSHHSPPLTMAKMHAPRGGTLLQFFSTDDMPLARAAAFWSAHVFQCEDVRASSARAFHGHGFLCRC
ERGRFVRFRGASLDTRIGAAWLSAAPADAYVTICALHAGECTVEAPGLPDVRFRANELFMLDGGQPMRVRWSEPCFSALR
LPRASVGRTLGQAAMDASPSAASLQEARLAPFLAAELALIGGRGPTLSSDELDYMLARAAELGRTLLQAALSSRARRGAP
ARADRLQAAYRYIEQHLHLPTLTPERIADAIHCSRTQLYRLFRHESQTVKAALREARLNRSLGYLEQPEVTLSIGEIAHA
CGFPDQSTFGKLFRRRFGRTPGEVRRAARGCSI*

  Nucleotide sequence of regulator: 1062 bp    .

>REG0126 NC_006349:c1647593-1646532 [Burkholderia mallei ATCC 23344]
ATGCCACATGCGTTCCGCACGGATTCTCGCCCAACGCGCTTCCCGTCGCACCATTCACCGCCCCTCACCATGGCGAAGAT
GCACGCGCCCCGCGGCGGCACGCTGCTGCAATTCTTTTCGACCGACGACATGCCGCTCGCGCGCGCGGCGGCGTTCTGGA
GCGCGCACGTGTTCCAGTGCGAGGACGTGCGCGCGTCGTCCGCGCGCGCGTTTCACGGGCACGGCTTTCTCTGCCGCTGC
GAGCGCGGCCGGTTCGTTCGCTTTCGCGGCGCGTCGCTCGACACGCGCATCGGCGCGGCGTGGCTGAGCGCCGCGCCAGC
CGATGCGTACGTGACGATCTGCGCGCTGCATGCGGGCGAGTGCACGGTCGAAGCGCCCGGCTTGCCGGATGTGCGCTTTC
GTGCGAACGAGCTGTTCATGCTGGACGGCGGTCAGCCGATGCGCGTGCGCTGGAGCGAGCCGTGTTTCAGCGCGCTCAGG
CTGCCGCGCGCATCGGTGGGGCGTACGCTCGGCCAGGCGGCGATGGACGCGTCGCCGAGCGCGGCTTCGTTGCAGGAGGC
GCGGCTCGCGCCGTTTCTCGCGGCGGAGCTCGCGCTGATCGGCGGTCGCGGCCCGACGCTGTCGTCGGACGAGCTCGATT
ACATGCTCGCGCGCGCAGCCGAGCTCGGCCGCACGCTGCTTCAGGCGGCGCTGTCGTCGCGCGCGCGGCGCGGCGCGCCC
GCGCGCGCCGACCGGCTGCAGGCCGCGTATCGCTACATCGAGCAGCATCTTCATCTGCCGACGCTCACACCCGAGCGGAT
CGCCGACGCGATCCATTGCTCGCGCACGCAGCTCTATCGGCTGTTCCGCCATGAATCGCAGACGGTGAAGGCGGCGCTGC
GCGAGGCGCGGCTGAACCGCAGCCTCGGCTATCTCGAGCAGCCCGAGGTTACGCTCAGCATCGGCGAGATCGCGCATGCT
TGCGGTTTTCCCGATCAGTCGACGTTCGGCAAGCTGTTTCGCCGGCGCTTCGGCAGAACGCCCGGCGAGGTGCGCCGCGC
CGCGCGGGGATGTTCGATATGA