Detailed information of immunity protein


Summary

Immunity protein ID IMU00363 experimental
Cognate effector -
Related T6SS (Type) T6SS00926 experimental (Type iii)
Strain Bacteroides fragilis 638R
Replicon chromosome
Sequence Protein sequence (349 a.a.); Nucleotide sequence (1047 bp)
Description AID-1 system genes grant immunity against corresponding T6SS effectors
Reference
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
External database links

Locus tag (Gene) BF638R_RS09665 (i6)
Coordinates (Strand) 2411584..2412630 (+)
NCBI ID 504064776
RefSeq NC_016776
Uniprot ID E1WW09_BACF6
KEGG ID bfg:BF638R_2053
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-34 MKGHKHSLNKYHQWADEVQVGKEAEQREERKWKK
Transmembrane helix 35-57 IFFIMALCVSLSFCAVFFVTCSL
Outside 58-66 FETATITNL
Transmembrane helix 67-89 ALSVVMMLVITSAWLIMILYLII
Inside 90-143 PKIYPKIPLINNVQLKYYGCFDFGNKWVSENIEVFKQFDDKKIIIDATSPTRNG
Transmembrane helix 144-161 AAILYIAILITLALFDFY
Outside 162-206 PKVYDNLLDGDIWGTTQAYTVYHRILDERGVLFTNNDNVMINKLS
Transmembrane helix 207-229 FASNMALASVYAIFILLALLSVL
Inside 230-348 SPRRTVIFDREKKTITIPPRWRIHKAETIPFYDAVITFGAKVDQKSFKGDEEIVIANYKHLVKGVSLQFAGRTNGYCFARLIQAYMTEDDLSNHPEFEAFKQIQEEMRINKLRKEAEKQ


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9286 - -


  Protein sequence: 349 a.a.    .

>IMU00363 NC_016776:2411584-2412630 [Bacteroides fragilis 638R]
MKGHKHSLNKYHQWADEVQVGKEAEQREERKWKKIFFIMALCVSLSFCAVFFVTCSLFETATITNLALSVVMMLVITSAW
LIMILYLIIPKIYPKIPLINNVQLKYYGCFDFGNKWVSENIEVFKQFDDKKIIIDATSPTRNGAAILYIAILITLALFDF
YPKVYDNLLDGDIWGTTQAYTVYHRILDERGVLFTNNDNVMINKLSFASNMALASVYAIFILLALLSVLSPRRTVIFDRE
KKTITIPPRWRIHKAETIPFYDAVITFGAKVDQKSFKGDEEIVIANYKHLVKGVSLQFAGRTNGYCFARLIQAYMTEDDL
SNHPEFEAFKQIQEEMRINKLRKEAEKQ*

  Nucleotide sequence: 1047 bp    .

>IMU00363 NC_016776:2411584-2412630 [Bacteroides fragilis 638R]
ATGAAAGGTCATAAACATTCTCTTAATAAGTATCATCAATGGGCTGATGAGGTTCAAGTAGGAAAAGAGGCAGAACAAAG
GGAAGAACGGAAATGGAAAAAGATTTTTTTCATTATGGCATTATGCGTTAGTTTATCATTTTGTGCTGTATTTTTTGTCA
CCTGTTCTCTTTTTGAAACGGCAACAATCACTAATCTTGCTCTTTCGGTAGTAATGATGTTAGTTATTACTTCTGCTTGG
CTTATTATGATACTTTATTTAATAATCCCCAAGATATATCCTAAAATTCCTCTTATCAATAACGTCCAACTTAAGTATTA
TGGTTGTTTCGATTTCGGAAATAAATGGGTTAGTGAAAATATAGAGGTATTTAAGCAGTTTGATGACAAGAAAATCATCA
TAGATGCAACCTCCCCGACTCGAAATGGTGCAGCAATTTTGTATATTGCAATTTTGATAACATTGGCATTATTTGATTTC
TATCCTAAAGTATATGACAACCTATTAGATGGAGATATCTGGGGGACTACTCAAGCTTATACTGTTTATCACAGAATTCT
GGATGAGCGAGGTGTATTATTTACAAATAATGATAACGTCATGATAAATAAACTCTCGTTTGCAAGCAATATGGCATTAG
CATCTGTTTATGCAATTTTCATTCTATTAGCACTACTTTCCGTTTTATCCCCCCGACGAACAGTTATCTTCGACCGGGAA
AAGAAAACAATCACCATTCCTCCGCGTTGGAGGATACACAAAGCGGAAACTATACCGTTTTATGATGCCGTTATTACATT
TGGTGCTAAAGTAGATCAAAAATCATTTAAGGGAGATGAGGAAATAGTAATAGCTAATTACAAACACCTCGTCAAGGGAG
TTTCTTTGCAGTTTGCTGGTCGTACAAACGGGTATTGTTTTGCTCGTTTGATTCAAGCTTATATGACTGAAGACGATTTA
TCAAATCATCCTGAATTTGAAGCTTTCAAACAGATACAAGAGGAAATGAGAATAAACAAACTACGGAAAGAGGCTGAAAA
GCAATAA