Detailed information of effector

Summary

Effector ID	EFF76633
Effector type	-
Cognate immunity protein	-
Related T6SS (Type)	T6SS17502 (Type Unknown)
Strain	Citrobacter freundii strain CF74
Replicon	chromosome
Sequence	-
Description	Hcp-2 contributed to CF74-induced IL-1β secretion via NLRP3 activation and caspase 1 activation in BMMs
Reference	[1] Liu L, Song L, Deng R, et al. Citrobacter freundii Activation of NLRP3 Inflammasome via the Type VI Secretion System. J Infect Dis. 2021 Jun 15;223(12):2174-2185. doi: 10.1093/infdis/jiaa692. PMID: 33151309

Experimental investigation has been performed.
Bioinformatics investigation has been performed

---

External database links

Locus tag (Gene)	hcp-2
Coordinates (Strand)	-
NCBI ID	-
GenBank	-
Uniprot ID	-
KEGG ID	-
PDB ID	-

---

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region

---