Detailed information of effector


Summary

Effector ID EFF01493 experimental
Effector type Tse
Cognate immunity protein -
Related T6SS (Type) T6SS00158 experimental (Type ii)
Strain Francisella tularensis subsp. novicida U112
Replicon chromosome
Sequence Protein sequence (493 a.a.); Nucleotide sequence (1479 bp)
Description OpiB-3
Reference
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed

External database links

Locus tag (Gene) FTN_1071 (OpiB-3)
Coordinates (Strand) 1132421..1133899 (-)
NCBI ID 118497662
RefSeq NC_008601
Uniprot ID UPI0000E89708
KEGG ID -
PDB ID -

Pfam domain hit(s)

Domain Pfam ID E-value Aligned region

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-492 MAIDLLKLQKKLGYDVDTGGMCYGIAYMAIQAIIRDDLVTYISRIEYLEKTLSQHNNNQDAAINEIVEKINVAYEKRKNKQNLDCDEIKLLDILNWFDGVQIYHNYNNVLSGGRNYEIATNFFSANTNQNEKENRKIFVIAKELNILTKELIDDIFDKIDNSKEPIAFSLSTPDHIISIGKSSNYKPIYLINHDIHKHILNERSLYSEVFCAFKYSMRIALSIFRYSYQEENISIKYVTNNLDKDDLCNLLCLALQDGYVEAIKVYIEGISNLSGINKQQLLAAKKKNDGAPGLCLALQNGHSEAIKVYIEVISNLSGINKQELLAAKKQNGTPGLFMALQEGHAEAIKVYIEGIFNLSGINKQQLLAAKRSDGTPGLSVALYCGHAEAIKTYIEGITNLSGINKQELLAAKISDGTPGLFMALQNGHAEAIKAYIEGIFNIPGINRRELLAAKTLDGTPGLNIALQQGHSQAAKTYKETISKFMMLRNGLP



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9947 - -



  Protein sequence: 493 a.a.    .

>EFF01493 NC_008601:c1133899-1132421 Type VI Secretion System Effector (Tse) [Francisella tularensis subsp. novicida U112]
MAIDLLKLQKKLGYDVDTGGMCYGIAYMAIQAIIRDDLVTYISRIEYLEKTLSQHNNNQDAAINEIVEKINVAYEKRKNK
QNLDCDEIKLLDILNWFDGVQIYHNYNNVLSGGRNYEIATNFFSANTNQNEKENRKIFVIAKELNILTKELIDDIFDKID
NSKEPIAFSLSTPDHIISIGKSSNYKPIYLINHDIHKHILNERSLYSEVFCAFKYSMRIALSIFRYSYQEENISIKYVTN
NLDKDDLCNLLCLALQDGYVEAIKVYIEGISNLSGINKQQLLAAKKKNDGAPGLCLALQNGHSEAIKVYIEVISNLSGIN
KQELLAAKKQNGTPGLFMALQEGHAEAIKVYIEGIFNLSGINKQQLLAAKRSDGTPGLSVALYCGHAEAIKTYIEGITNL
SGINKQELLAAKISDGTPGLFMALQNGHAEAIKAYIEGIFNIPGINRRELLAAKTLDGTPGLNIALQQGHSQAAKTYKET
ISKFMMLRNGLP*

  Nucleotide sequence: 1479 bp    .

>EFF01493 NC_008601:c1133899-1132421 Type VI Secretion System Effector (Tse) [Francisella tularensis subsp. novicida U112]
ATGGCTATTGATCTATTAAAACTACAAAAAAAACTTGGATATGATGTTGATACTGGTGGAATGTGTTACGGAATAGCTTA
TATGGCTATACAAGCTATTATAAGAGATGATTTAGTAACATATATTAGCAGAATAGAATATTTAGAAAAAACATTATCGC
AACATAACAATAATCAAGATGCTGCGATTAATGAAATTGTAGAAAAGATAAATGTAGCATATGAAAAAAGGAAGAATAAA
CAAAATTTAGATTGTGATGAAATAAAATTATTGGATATATTAAATTGGTTTGATGGAGTTCAAATATACCATAATTACAA
TAATGTATTATCTGGAGGTCGAAATTATGAGATTGCAACAAACTTTTTCTCAGCTAATACAAATCAAAATGAAAAAGAAA
ATAGAAAAATCTTTGTTATAGCTAAAGAATTAAATATATTAACAAAAGAGTTGATAGATGATATTTTTGATAAGATTGAT
AACAGTAAAGAACCTATTGCTTTTTCATTAAGCACCCCAGATCATATTATTTCGATAGGTAAAAGCTCTAATTATAAACC
GATATATTTAATCAATCATGATATTCATAAACATATATTAAATGAGAGATCGTTATACAGTGAAGTATTTTGTGCATTTA
AGTATTCGATGAGGATAGCTTTGAGCATTTTTAGATATTCATACCAAGAAGAAAATATTTCAATTAAATATGTCACTAAT
AATTTAGATAAAGATGATTTATGTAACTTATTATGTCTAGCTTTGCAAGATGGATACGTAGAAGCTATCAAAGTTTATAT
AGAAGGTATATCTAATCTTAGTGGAATTAATAAACAACAACTATTAGCTGCTAAAAAGAAAAATGATGGAGCTCCAGGAT
TATGTCTAGCTTTACAAAATGGCCACTCAGAAGCTATCAAAGTTTATATAGAGGTGATATCTAATCTTAGTGGAATTAAT
AAACAAGAATTATTAGCTGCTAAAAAACAAAATGGAACACCAGGGTTATTTATGGCTTTACAAGAAGGCCACGCAGAAGC
TATCAAAGTTTATATAGAGGGGATATTTAATCTTAGTGGAATTAATAAACAACAACTATTAGCTGCTAAAAGGAGTGATG
GAACACCAGGATTATCTGTGGCTTTGTATTGTGGCCACGCAGAAGCTATCAAAACCTATATTGAAGGTATAACTAATCTT
AGTGGAATTAACAAACAAGAACTATTAGCTGCTAAAATATCGGATGGAACACCTGGGTTATTTATGGCTTTACAAAATGG
CCACGCAGAAGCTATCAAAGCTTATATAGAGGGTATATTTAATATTCCTGGAATTAATAGACGAGAATTGTTAGCTGCTA
AAACCCTGGATGGAACACCTGGGTTGAATATAGCTTTGCAACAGGGTCATTCACAAGCTGCTAAAACTTATAAAGAAACG
ATATCTAAATTCATGATGTTAAGGAATGGATTACCATGA