Detailed information of effector


Summary

Effector ID EFF01492 experimental
Effector type Tse
Cognate immunity protein -
Related T6SS (Type) T6SS00158 experimental (Type ii)
Strain Francisella tularensis subsp. novicida U112
Replicon chromosome
Sequence Protein sequence (451 a.a.); Nucleotide sequence (1353 bp)
Description OpiB-2
Reference
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
External database links

Locus tag (Gene) FTN_1070 (OpiB-2)
Coordinates (Strand) 1130861..1132213 (-)
NCBI ID 118497661
RefSeq NC_008601
Uniprot ID UPI0000E89707
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-450 MAIDLLKLQKKLGYDVDTGGMCYGIAYMAIQAIIRDDLAAYISRIEYLEKTLSQHNNNEDAAINEIVEKINVAYEKRKNKQNLDCDEIKLLDILNWLDGVQIYHNYNNLLSGGQNYKNATNFFSANTNQNEKENRKIFVIAKELNILTKELINDIFDKIDNSKEPIAFSLSAPGHIISIGKSSNYKPIYLVNHNIHKHILNKKSLYSEVFCTFKYSMRIALSIFRYSYQEENISIKYVTNNLDKDDLCNLLCLALQNGHTEAIKVYIEGISNLSGINKQQLLAAKRENDGTPGLCLALCNGHVEAIKVYIEEISNFPGIDKQQLLAAKNQRGTPGLFIALQQGHAEAIKAYIEGIFNLSGIDIQGLLAAKISDGTPGLFMALQNGHAEAIKAYIEGIFNIPGINRRELLAAKTLDGTPGLNIALQQGHSQAAKTYKETISKFMMLRNGLP


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9949 - -


  Protein sequence: 451 a.a.    .

>EFF01492 NC_008601:c1132213-1130861 Type VI Secretion System Effector (Tse) [Francisella tularensis subsp. novicida U112]
MAIDLLKLQKKLGYDVDTGGMCYGIAYMAIQAIIRDDLAAYISRIEYLEKTLSQHNNNEDAAINEIVEKINVAYEKRKNK
QNLDCDEIKLLDILNWLDGVQIYHNYNNLLSGGQNYKNATNFFSANTNQNEKENRKIFVIAKELNILTKELINDIFDKID
NSKEPIAFSLSAPGHIISIGKSSNYKPIYLVNHNIHKHILNKKSLYSEVFCTFKYSMRIALSIFRYSYQEENISIKYVTN
NLDKDDLCNLLCLALQNGHTEAIKVYIEGISNLSGINKQQLLAAKRENDGTPGLCLALCNGHVEAIKVYIEEISNFPGID
KQQLLAAKNQRGTPGLFIALQQGHAEAIKAYIEGIFNLSGIDIQGLLAAKISDGTPGLFMALQNGHAEAIKAYIEGIFNI
PGINRRELLAAKTLDGTPGLNIALQQGHSQAAKTYKETISKFMMLRNGLP*

  Nucleotide sequence: 1353 bp    .

>EFF01492 NC_008601:c1132213-1130861 Type VI Secretion System Effector (Tse) [Francisella tularensis subsp. novicida U112]
ATGGCTATTGATCTATTAAAACTACAAAAAAAACTTGGATATGATGTTGATACTGGTGGAATGTGTTACGGAATAGCTTA
TATGGCTATACAAGCTATTATAAGAGATGATTTAGCAGCATATATTAGCAGAATAGAATATTTAGAAAAAACATTATCGC
AACATAACAATAATGAAGATGCTGCGATTAATGAAATTGTAGAAAAAATAAATGTAGCATATGAAAAAAGGAAGAATAAA
CAAAATTTAGATTGTGATGAAATAAAATTATTGGATATATTAAATTGGCTTGATGGAGTTCAAATATATCACAATTACAA
TAATCTATTATCTGGAGGTCAAAATTATAAGAATGCAACAAACTTTTTCTCAGCTAATACAAATCAAAATGAAAAAGAAA
ATAGAAAAATCTTTGTTATAGCTAAAGAATTAAATATATTAACAAAAGAGTTGATAAATGATATTTTTGATAAGATTGAT
AACAGTAAAGAACCTATTGCTTTTTCATTAAGCGCCCCAGGTCATATTATTTCGATAGGTAAAAGCTCTAATTATAAACC
GATATATTTAGTTAATCATAATATTCATAAACATATATTAAATAAGAAATCGTTATACAGTGAAGTATTTTGTACATTTA
AGTATTCGATGAGGATAGCTTTGAGCATTTTTAGATATTCATACCAAGAAGAAAATATTTCAATTAAATATGTCACTAAT
AATTTAGATAAAGATGATTTATGTAACTTATTATGTCTAGCTTTACAAAATGGCCACACAGAAGCTATCAAAGTTTATAT
AGAAGGTATATCTAATCTTAGTGGAATTAATAAACAACAACTATTAGCTGCTAAAAGGGAAAATGATGGAACACCAGGAT
TATGTCTAGCTTTGTGTAATGGTCACGTAGAAGCTATCAAAGTTTATATAGAGGAGATATCTAATTTTCCTGGAATTGAT
AAACAACAACTATTAGCTGCTAAAAATCAGCGTGGAACACCAGGGTTATTTATAGCTTTGCAACAGGGTCATGCAGAAGC
TATCAAAGCTTATATAGAGGGGATATTTAATCTTAGTGGAATTGATATACAAGGATTATTAGCTGCTAAAATATCGGATG
GAACACCAGGGTTATTTATGGCTTTGCAAAATGGTCATGCAGAAGCTATCAAAGCTTATATAGAGGGTATATTTAATATT
CCTGGAATTAATAGACGAGAATTGTTAGCTGCTAAAACCCTGGATGGAACACCTGGGTTGAATATAGCTTTGCAACAGGG
TCATTCACAAGCTGCTAAAACTTATAAAGAAACGATATCTAAATTCATGATGTTAAGGAATGGATTACCATGA