Detailed information of effector


Summary

Effector ID EFF01491 experimental
Effector type Tse
Cognate immunity protein -
Related T6SS (Type) T6SS00158 experimental (Type ii)
Strain Francisella tularensis subsp. novicida U112
Replicon chromosome
Sequence Protein sequence (833 a.a.); Nucleotide sequence (2499 bp)
Description OpiB-1
Reference
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
External database links

Locus tag (Gene) FTN_1069 (OpiB-1)
Coordinates (Strand) 1128155..1130653 (-)
NCBI ID 118497660
RefSeq NC_008601
Uniprot ID UPI0000E89706
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-832 MAIDLLKLQKKLGYDVDTGGMCYGIAYMAIQAIIRDDLAAYISRIEYLEKTLSQHNNNEDAAINEIVEKINVAYEKRKNKQNLDCDEIKLLDILNWLDGVQIYHNYNNLLYGGQNYKNATNFFSANTNQNEKENRKIFVIAKELNILTKELIDDIFDKIDNSKEPIAFSLSTPDHIISIGKSSNYKPIYLINHDIHKHILNERSLYSEVFCAFKYSMRIALSIFRYSYQEENISIKYVTNNLDKDDLCNLLCLALQDGYVEAIKVYIEGISNLSGINKQQLLAAKKKNDGAPGLCLALQNGHAEAIKAYIEGIFNIPGIDKQQLLAAKRKDGTPGLFMALQNGHAEAIKVYIEGISNLSGINKQQLLAAKRKDGTPGLYIALQNGHVEAIKIYIDAISNLGGIDKQELLAAKIPDGTPGLYVALYNGHAEAIKVYIEAISNFPGIDKQELLAAKMSDGTPGLCLALQNGHAEAIKVYIEEISNFPGIDKQELLAAKMPDGTPGLFMALQNGHAEAIKVYIEAIFNLPGINKQQLLTPKMSDGTPGLFIALQNGHAEAIKIYIEGISNLSGINKQQLLTPKMSDGTPGLFMALQNGHAEAIKVYIEGISNFPGIDKQQLLAAKRKDGTPGLCLALQNGHVEAIKIYIDAISNLGGIDKQELLAAKIPDGTPGLYVALYNGHAEAIKVYIDAISNLSGIDKQQLLAAKKQNGTPGLFMALQKGHAEAIKAYIEGISNFSGIDKQQLLAAKNQRGTPALCMALYNGHAEAIKVYIEGIFNLPGINRRELLAAKMPDGTPGLHIALQQGHSQAVKTYREMISKLKILSNGLPGFLL


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9949 - -


  Protein sequence: 833 a.a.    .

>EFF01491 NC_008601:c1130653-1128155 Type VI Secretion System Effector (Tse) [Francisella tularensis subsp. novicida U112]
MAIDLLKLQKKLGYDVDTGGMCYGIAYMAIQAIIRDDLAAYISRIEYLEKTLSQHNNNEDAAINEIVEKINVAYEKRKNK
QNLDCDEIKLLDILNWLDGVQIYHNYNNLLYGGQNYKNATNFFSANTNQNEKENRKIFVIAKELNILTKELIDDIFDKID
NSKEPIAFSLSTPDHIISIGKSSNYKPIYLINHDIHKHILNERSLYSEVFCAFKYSMRIALSIFRYSYQEENISIKYVTN
NLDKDDLCNLLCLALQDGYVEAIKVYIEGISNLSGINKQQLLAAKKKNDGAPGLCLALQNGHAEAIKAYIEGIFNIPGID
KQQLLAAKRKDGTPGLFMALQNGHAEAIKVYIEGISNLSGINKQQLLAAKRKDGTPGLYIALQNGHVEAIKIYIDAISNL
GGIDKQELLAAKIPDGTPGLYVALYNGHAEAIKVYIEAISNFPGIDKQELLAAKMSDGTPGLCLALQNGHAEAIKVYIEE
ISNFPGIDKQELLAAKMPDGTPGLFMALQNGHAEAIKVYIEAIFNLPGINKQQLLTPKMSDGTPGLFIALQNGHAEAIKI
YIEGISNLSGINKQQLLTPKMSDGTPGLFMALQNGHAEAIKVYIEGISNFPGIDKQQLLAAKRKDGTPGLCLALQNGHVE
AIKIYIDAISNLGGIDKQELLAAKIPDGTPGLYVALYNGHAEAIKVYIDAISNLSGIDKQQLLAAKKQNGTPGLFMALQK
GHAEAIKAYIEGISNFSGIDKQQLLAAKNQRGTPALCMALYNGHAEAIKVYIEGIFNLPGINRRELLAAKMPDGTPGLHI
ALQQGHSQAVKTYREMISKLKILSNGLPGFLL*

  Nucleotide sequence: 2499 bp    .

>EFF01491 NC_008601:c1130653-1128155 Type VI Secretion System Effector (Tse) [Francisella tularensis subsp. novicida U112]
ATGGCTATTGATCTATTAAAACTACAAAAAAAACTTGGATATGATGTTGATACTGGTGGAATGTGTTACGGAATAGCTTA
TATGGCTATACAAGCTATTATAAGAGATGATTTAGCAGCATATATTAGCAGAATAGAATATTTAGAAAAAACATTATCGC
AACATAACAATAATGAAGATGCTGCGATTAATGAAATTGTAGAAAAAATAAATGTAGCATATGAAAAAAGGAAGAATAAA
CAAAATCTAGATTGTGATGAAATAAAATTATTAGATATATTAAATTGGCTTGATGGAGTTCAAATATACCACAATTACAA
TAATCTATTATATGGAGGTCAAAATTATAAGAATGCAACAAACTTTTTCTCAGCTAATACAAATCAAAATGAAAAAGAAA
ATAGAAAAATCTTTGTTATAGCTAAAGAATTAAATATATTAACAAAAGAGTTGATAGATGATATTTTTGATAAGATTGAT
AACAGTAAAGAACCTATTGCTTTTTCATTAAGCACCCCAGATCATATTATTTCGATAGGTAAAAGCTCTAATTATAAACC
GATATATTTAATCAATCATGATATTCATAAACATATATTAAATGAGAGATCGTTATACAGTGAAGTATTTTGTGCATTTA
AGTATTCGATGAGGATAGCTTTGAGCATTTTTAGATATTCATACCAAGAAGAAAATATTTCAATTAAATATGTCACTAAT
AATTTAGATAAAGATGATTTATGTAACTTATTATGTCTAGCTTTGCAAGATGGATACGTAGAAGCTATCAAAGTTTATAT
AGAAGGTATATCTAATCTTAGTGGAATTAATAAACAACAACTATTAGCTGCTAAAAAGAAAAATGATGGAGCTCCAGGAT
TATGTCTAGCTTTACAAAATGGCCACGCAGAAGCTATCAAAGCTTATATAGAGGGTATATTTAATATTCCTGGAATTGAT
AAACAACAACTATTAGCTGCTAAAAGGAAGGATGGAACACCAGGGTTATTTATGGCTTTGCAAAATGGCCACGCAGAAGC
TATCAAAGTTTATATAGAAGGTATATCTAATCTTAGTGGAATTAATAAACAACAACTATTAGCTGCTAAAAGGAAGGATG
GAACACCGGGATTATATATTGCTTTGCAAAATGGTCACGTAGAAGCTATCAAAATTTATATAGATGCGATATCTAATCTT
GGTGGAATTGATAAACAAGAATTATTAGCTGCTAAAATACCGGATGGAACACCGGGATTATATGTGGCTTTGTATAATGG
TCACGCAGAAGCTATCAAAGTTTATATAGAGGCGATATCTAATTTTCCTGGAATTGATAAACAAGAATTATTAGCTGCTA
AAATGTCAGATGGAACACCAGGGTTATGTCTAGCTTTGCAAAATGGTCACGCAGAAGCTATCAAAGTTTATATAGAGGAG
ATATCTAATTTTCCTGGAATTGATAAACAAGAATTATTAGCTGCTAAAATGCCGGATGGAACACCAGGGTTATTTATGGC
TTTGCAAAATGGTCACGCAGAAGCTATCAAAGTTTATATAGAGGCGATATTTAATCTTCCTGGAATTAACAAACAACAAC
TATTAACTCCTAAAATGTCAGATGGAACACCAGGGTTATTTATAGCTTTGCAAAATGGTCACGCAGAAGCTATCAAAATT
TATATAGAGGGGATATCTAATCTTAGTGGAATTAATAAACAACAACTATTAACTCCTAAAATGTCAGATGGAACACCAGG
GTTATTTATGGCTTTGCAAAATGGTCACGCAGAAGCTATCAAAGTTTATATAGAGGGGATATCTAATTTTCCTGGAATTG
ATAAACAACAACTATTAGCTGCTAAAAGGAAGGATGGAACACCAGGGTTATGTCTAGCTTTGCAAAATGGTCACGTAGAA
GCTATCAAAATTTATATAGATGCGATATCTAATCTTGGTGGAATTGATAAACAAGAATTATTAGCTGCTAAAATACCGGA
TGGAACACCGGGATTATATGTGGCTTTGTATAATGGTCACGCAGAAGCTATCAAAGTTTATATAGATGCGATATCTAATC
TTAGTGGAATTGATAAACAACAACTATTAGCTGCTAAAAAACAGAATGGAACACCAGGGTTATTTATGGCTTTGCAAAAA
GGTCACGCAGAAGCTATCAAAGCCTATATTGAAGGTATATCTAATTTTAGTGGAATTGATAAACAACAACTATTAGCTGC
TAAAAATCAGCGTGGAACACCAGCATTGTGTATGGCTTTGTATAATGGCCACGCAGAAGCTATCAAAGTTTATATAGAGG
GGATATTTAATCTTCCTGGAATTAATAGACGAGAATTATTAGCTGCTAAAATGCCGGATGGAACACCAGGGTTACATATA
GCTTTGCAACAGGGTCATTCACAAGCTGTTAAAACTTATAGAGAAATGATATCTAAATTGAAGATCTTAAGTAATGGATT
ACCAGGATTTTTGCTTTAG