SecReT6, T6SS database

Detailed information of effector

Summary

Effector ID	EFF01123
Effector type	-
Cognate immunity protein	-
Related T6SS (Type)	T6SS00838 (Type i1)
Strain	Proteus mirabilis BB2000
Replicon	chromosome
Sequence	Protein sequence (173 a.a.); Nucleotide sequence (519 bp)
Description	-
Reference	[1] Wenren LM, Sullivan NL, Cardarelli L, et al. Two independent pathways for self-recognition in Proteus mirabilis are linked by type VI-dependent export. mBio. 2013 Jul 23;4(4). pii: e00374-13. doi: 10.1128/mBio.00374-13. PMID: 23882014

Experimental investigation has been performed.

Bioinformatics investigation has been performed

External database links

Locus tag (Gene)	BB2000_RS14595
Coordinates (Strand)	3275686..3276204 (+)
NCBI ID	529238652
RefSeq	NC_022000
Uniprot ID	UPI00017A2F33
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
T6SS_HCP	PF05638.14	6.1e-35	7..155

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-172	MPTPCYISIEGKTQGNITAGAFTADSVGNIYVQGHEDQMLVQAFSHVVTVPTDPQSGQPSGQRAHKPFRFTVALNKAVPLLYNALASGEMLPKVELKWYRTSVEGKQEHFFTTTLTDATIVNIDCQMPHCQDPAKADFTQLIEVSLSYRKVDWEHTVAGTSGADDWRAPLEA

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9681	-	-

Protein sequence: 173 a.a. .

                                    >EFF01123 NC_022000:3275686-3276204  (Unknown) [Proteus mirabilis BB2000]
MPTPCYISIEGKTQGNITAGAFTADSVGNIYVQGHEDQMLVQAFSHVVTVPTDPQSGQPSGQRAHKPFRFTVALNKAVPL
LYNALASGEMLPKVELKWYRTSVEGKQEHFFTTTLTDATIVNIDCQMPHCQDPAKADFTQLIEVSLSYRKVDWEHTVAGT
SGADDWRAPLEA*

                                

Nucleotide sequence: 519 bp .

                                    >EFF01123 NC_022000:3275686-3276204  (Unknown) [Proteus mirabilis BB2000]
ATGCCAACTCCTTGCTATATTTCCATTGAAGGAAAAACTCAGGGCAACATCACTGCAGGCGCGTTTACTGCAGATTCTGT
CGGCAACATTTATGTACAAGGTCATGAAGACCAAATGTTGGTACAAGCATTTTCTCACGTGGTGACGGTTCCGACCGATC
CACAATCAGGACAACCTTCCGGCCAACGTGCGCATAAACCATTTCGTTTTACCGTGGCATTAAATAAAGCGGTTCCCCTG
CTGTATAACGCATTGGCTTCCGGCGAAATGTTGCCAAAAGTCGAGCTAAAATGGTATCGCACCTCGGTAGAAGGTAAACA
AGAGCACTTCTTTACCACCACACTGACTGACGCGACTATCGTGAACATCGATTGCCAAATGCCTCATTGCCAAGATCCGG
CTAAAGCCGACTTCACGCAACTTATCGAAGTCTCCCTCTCTTACCGCAAAGTTGACTGGGAGCATACTGTTGCCGGGACT
TCAGGTGCAGATGACTGGCGTGCACCACTCGAAGCATAA

                                