Detailed information of effector
Summary
| Effector ID | EFF00088  |
| Effector type | - |
| Cognate immunity protein | - |
| Related T6SS (Type) | T6SS00070 (Type i1) |
| Strain | Burkholderia mallei ATCC 23344 |
| Replicon | chromosome |
| Sequence | Protein sequence (170 a.a.); Nucleotide sequence (510 bp) |
| Description | Hcp protein |
| Reference |
Experimental investigation has been performed.
Bioinformatics investigation has been performedExternal database links
| Locus tag (Gene) | BMA_RS19605 |
| Coordinates (Strand) | 759926..760435 (-) |
| NCBI ID | 77358963 |
| RefSeq | NC_006349 |
| Uniprot ID | A0A0H2XFE5_BURMA |
| KEGG ID | bma:BMAA0742 |
| PDB ID | - |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| T6SS_HCP | PF05638.14 | 7.4e-23 | 6..155 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-169 | MLAGIYLKVKGKTQGEIKGSVVQEGHDGKIHILAFKNDYDMPARLQEGLTPAAAARGTITLTKEMDRSSPQFLQALGKREMMEEFEITIHRPKTDTTGGDLTELLFTYKFEKVLITHMDQYSPTPHKDDSNGIKEGLLGYIEEIKFAYSGYSLEHAESGIAGAANWTNG |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9812 | - | - |
Protein sequence: 170 a.a. .
>EFF00088 NC_006349:c760435-759926 (Unknown) [Burkholderia mallei ATCC 23344]
MLAGIYLKVKGKTQGEIKGSVVQEGHDGKIHILAFKNDYDMPARLQEGLTPAAAARGTITLTKEMDRSSPQFLQALGKRE
MMEEFEITIHRPKTDTTGGDLTELLFTYKFEKVLITHMDQYSPTPHKDDSNGIKEGLLGYIEEIKFAYSGYSLEHAESGI
AGAANWTNG*
MLAGIYLKVKGKTQGEIKGSVVQEGHDGKIHILAFKNDYDMPARLQEGLTPAAAARGTITLTKEMDRSSPQFLQALGKRE
MMEEFEITIHRPKTDTTGGDLTELLFTYKFEKVLITHMDQYSPTPHKDDSNGIKEGLLGYIEEIKFAYSGYSLEHAESGI
AGAANWTNG*
Nucleotide sequence: 510 bp .
>EFF00088 NC_006349:c760435-759926 (Unknown) [Burkholderia mallei ATCC 23344]
ATGCTGGCCGGAATATATCTCAAGGTCAAAGGAAAAACCCAGGGGGAAATCAAAGGCTCCGTCGTTCAGGAAGGTCATGA
CGGGAAGATCCACATCCTCGCCTTCAAGAACGACTACGACATGCCCGCCAGGCTCCAGGAAGGCCTGACGCCCGCCGCCG
CCGCTCGCGGCACGATCACGTTGACGAAGGAAATGGACAGATCGTCGCCGCAATTCCTGCAGGCGCTCGGCAAGCGCGAG
ATGATGGAAGAGTTCGAGATCACGATCCACCGTCCGAAGACGGATACAACAGGTGGGGACCTGACCGAACTCCTGTTCAC
GTACAAGTTCGAAAAAGTGCTGATCACCCACATGGACCAATACTCGCCCACGCCGCACAAAGACGATAGCAACGGCATCA
AGGAAGGCTTGCTCGGCTATATCGAGGAGATCAAGTTCGCGTATTCGGGATACTCGTTGGAACACGCGGAATCGGGCATC
GCGGGCGCCGCAAACTGGACGAATGGCTGA
ATGCTGGCCGGAATATATCTCAAGGTCAAAGGAAAAACCCAGGGGGAAATCAAAGGCTCCGTCGTTCAGGAAGGTCATGA
CGGGAAGATCCACATCCTCGCCTTCAAGAACGACTACGACATGCCCGCCAGGCTCCAGGAAGGCCTGACGCCCGCCGCCG
CCGCTCGCGGCACGATCACGTTGACGAAGGAAATGGACAGATCGTCGCCGCAATTCCTGCAGGCGCTCGGCAAGCGCGAG
ATGATGGAAGAGTTCGAGATCACGATCCACCGTCCGAAGACGGATACAACAGGTGGGGACCTGACCGAACTCCTGTTCAC
GTACAAGTTCGAAAAAGTGCTGATCACCCACATGGACCAATACTCGCCCACGCCGCACAAAGACGATAGCAACGGCATCA
AGGAAGGCTTGCTCGGCTATATCGAGGAGATCAAGTTCGCGTATTCGGGATACTCGTTGGAACACGCGGAATCGGGCATC
GCGGGCGCCGCAAACTGGACGAATGGCTGA