Detailed information of component protein


Summary

Component ID T6CP259654
Component protein type TssM
T6SS ID (Type) T6SS01006 experimental (Type i4b)
Strain Burkholderia pseudomallei K96243
Replicon chromosome I
Sequence Protein sequence (1298 a.a.); Nucleotide sequence (3894 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) AQ15_1825
Coordinate (Strand) 2078288..2082181 (-)
NCBI ID AJX27634.1
GenBank CP009538
Uniprot ID -
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 6.9e-96 494..861
IcmF-related_N PF14331.8 1.1e-82 190..442
IcmF_C PF06744.14 1.2e-21 1130..1233
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-12 MQRFLNVLTHPR
Transmembrane helix 13-30 TLTIVGFAALAAVLFIAA
Outside 31-34 DALQ
Transmembrane helix 35-57 IGLVWAAVALGVALALWLATKLW
Inside 58-439 RRWRVRRANRQLGDMLEQQAETGKMSAAVAEPAKRAELDVLRTRLADTVKTIKTSKIGQVSGGSALYELPWYIVIGNPAAGKSSAVINSGLQFPFADKNSAVIHGIGGTRNCDWFFTTEGILLDTAGRYSVHEEDRSEWLGFLDLLKRYRPKAPINGIIVTASIAELTGNRPEFAINLAKNLRQRVQELTEKLEVFAPVYVMFTKADLITGFTEFFSSNDRQEYDRVWGATLPYEPDEKRDVVALFDQRFEELYDGLKEISVAQLSVSRGNKLSPGQLSFPLEFSTIKPALRSFLATLFEDNPFQYKPIFRGFYFTSALQEGETNSAAAQRIAHRFGLNSQSLPKPHSAFSKNGFFLRDLFSKVIFADRQTVRQFASPTKTR
Transmembrane helix 440-462 VRYATFFGFVAALALALGGWTWS
Outside 463-1297 TIGNQQLVSNVQADLDNVTRLQQNRNDLQSRLQAMDILEDRIEQLEQFRRDKPLSVSLGLYQGNRLEQHLLTEYYNGVRQILLAPVSDNLASFLKDVNAHPDQLAPMTRAPESGATPAGPMPVSTHPAAPGAAPSPAVAQGRQQGGLYNDASPTNVEDAYNALKTYLMLSDKRHVEQAHLTDQVARFWRGWLETNRGNMPRDEMIRSAERMITFYLSRVSDNDWPMIEANLALVDQTRENLRRVVRGMPARQRVYEEIKARASTRFAPMTIARIVGEGNTGLVAGSYAIPGTFTRDAWFQYVQPAIRDAATKELQAKDWVLNTASADDLTLEGSPEQIQKTLVAMYKTEYAQHWQKFMQGIAVQGFGNFTQAVDAMNKLGDPQDSPIRKVLETAYDQTSWDNPSLANATIKKAQTGVVNWVKQWFTRQPGGQIAANVDINGNPADVPMGPIGQEFVGLGRIVATHDGTSMLKGYMDTLSKVRTRFNVIKNQGDPGPGARQLMQQTLDGNGSELADSLKFVDEQMLTGLTDSQRKSLRPLLVRPLMQAFAVVIQPASVEVNKVWNAQVYQPFQNSLANKYPFAAGAKVEAGAGEIAQVFGPDGSIAKFVGTTLGPLAVRRGDTLSARTWGDMGLALTPDFTGGFARWVAPLAGGAATSAAASSEPQTVFQVLPQPSSGTTEYTIAIDGQQLRYRNTPPQWTNFVWPNPQGSPGATLSATTFDGRTLQLVNEPGRYGLEKLINSAQRKRRPDGTFDLTWTQGSVSVSVTMRIISTSQPTGGGDQPQQQSLRGLRLPSSVADASAGGAANATAQPGSGAAAAQVAATAASASNAQGAQ


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9944 - -


  Protein sequence: 1298 a.a.    

>T6CP259654 CP009538:c2082181-2078288 [Burkholderia pseudomallei K96243] [TssM]
MQRFLNVLTHPRTLTIVGFAALAAVLFIAADALQIGLVWAAVALGVALALWLATKLWRRWRVRRANRQLGDMLEQQAETG
KMSAAVAEPAKRAELDVLRTRLADTVKTIKTSKIGQVSGGSALYELPWYIVIGNPAAGKSSAVINSGLQFPFADKNSAVI
HGIGGTRNCDWFFTTEGILLDTAGRYSVHEEDRSEWLGFLDLLKRYRPKAPINGIIVTASIAELTGNRPEFAINLAKNLR
QRVQELTEKLEVFAPVYVMFTKADLITGFTEFFSSNDRQEYDRVWGATLPYEPDEKRDVVALFDQRFEELYDGLKEISVA
QLSVSRGNKLSPGQLSFPLEFSTIKPALRSFLATLFEDNPFQYKPIFRGFYFTSALQEGETNSAAAQRIAHRFGLNSQSL
PKPHSAFSKNGFFLRDLFSKVIFADRQTVRQFASPTKTRVRYATFFGFVAALALALGGWTWSTIGNQQLVSNVQADLDNV
TRLQQNRNDLQSRLQAMDILEDRIEQLEQFRRDKPLSVSLGLYQGNRLEQHLLTEYYNGVRQILLAPVSDNLASFLKDVN
AHPDQLAPMTRAPESGATPAGPMPVSTHPAAPGAAPSPAVAQGRQQGGLYNDASPTNVEDAYNALKTYLMLSDKRHVEQA
HLTDQVARFWRGWLETNRGNMPRDEMIRSAERMITFYLSRVSDNDWPMIEANLALVDQTRENLRRVVRGMPARQRVYEEI
KARASTRFAPMTIARIVGEGNTGLVAGSYAIPGTFTRDAWFQYVQPAIRDAATKELQAKDWVLNTASADDLTLEGSPEQI
QKTLVAMYKTEYAQHWQKFMQGIAVQGFGNFTQAVDAMNKLGDPQDSPIRKVLETAYDQTSWDNPSLANATIKKAQTGVV
NWVKQWFTRQPGGQIAANVDINGNPADVPMGPIGQEFVGLGRIVATHDGTSMLKGYMDTLSKVRTRFNVIKNQGDPGPGA
RQLMQQTLDGNGSELADSLKFVDEQMLTGLTDSQRKSLRPLLVRPLMQAFAVVIQPASVEVNKVWNAQVYQPFQNSLANK
YPFAAGAKVEAGAGEIAQVFGPDGSIAKFVGTTLGPLAVRRGDTLSARTWGDMGLALTPDFTGGFARWVAPLAGGAATSA
AASSEPQTVFQVLPQPSSGTTEYTIAIDGQQLRYRNTPPQWTNFVWPNPQGSPGATLSATTFDGRTLQLVNEPGRYGLEK
LINSAQRKRRPDGTFDLTWTQGSVSVSVTMRIISTSQPTGGGDQPQQQSLRGLRLPSSVADASAGGAANATAQPGSGAAA
AQVAATAASASNAQGAQ*

  Nucleotide sequence: 3894 bp    

>T6CP259654 CP009538:c2082181-2078288 [Burkholderia pseudomallei K96243] [TssM]
ATGCAACGCTTCCTCAACGTGTTGACTCACCCTCGCACGCTCACGATCGTCGGCTTCGCCGCGCTCGCGGCGGTTCTGTT
CATCGCGGCCGACGCGCTCCAGATCGGCCTCGTATGGGCGGCCGTCGCGCTCGGTGTCGCGCTCGCGCTCTGGCTCGCGA
CGAAGCTCTGGCGCCGCTGGCGCGTGCGCCGCGCGAACCGCCAGCTCGGCGACATGCTCGAGCAGCAGGCCGAAACGGGC
AAGATGTCCGCCGCCGTGGCCGAGCCCGCGAAGCGCGCGGAGCTCGACGTGCTGCGCACCCGCCTCGCCGACACGGTGAA
GACGATCAAGACTTCGAAAATCGGCCAGGTGTCGGGCGGCTCCGCGCTGTACGAACTGCCGTGGTACATCGTGATCGGCA
ATCCGGCCGCGGGCAAGAGCAGCGCCGTCATCAACTCGGGGTTGCAGTTTCCGTTCGCGGACAAGAACAGCGCGGTGATC
CACGGCATCGGCGGCACGCGCAACTGCGACTGGTTCTTCACGACCGAAGGCATCCTGCTCGACACCGCGGGCCGCTATTC
GGTGCACGAGGAAGACCGCAGCGAATGGCTCGGCTTTCTCGATCTGCTCAAGCGCTATCGCCCGAAGGCCCCGATCAACG
GCATCATCGTGACGGCGAGCATCGCCGAGCTCACCGGCAATCGCCCCGAATTCGCGATCAACCTCGCGAAAAACCTGCGC
CAGCGCGTGCAGGAGCTCACCGAGAAGCTCGAAGTGTTCGCGCCCGTCTACGTGATGTTCACGAAGGCCGACCTGATCAC
GGGCTTCACCGAATTCTTCAGCAGCAACGATCGCCAGGAATACGACCGCGTGTGGGGCGCGACGCTGCCGTACGAGCCTG
ACGAGAAGCGCGACGTGGTCGCGCTGTTCGATCAGCGCTTCGAGGAACTGTATGACGGGCTCAAGGAAATCAGCGTCGCG
CAGCTGTCGGTGAGCCGCGGCAACAAGCTCTCGCCCGGCCAGTTGAGCTTCCCGCTCGAATTCTCGACGATCAAGCCCGC
GCTGCGCTCGTTCCTCGCGACGCTGTTCGAGGACAACCCGTTCCAGTACAAGCCGATCTTCCGCGGCTTCTACTTCACGA
GCGCGCTGCAGGAAGGCGAAACGAACAGCGCGGCCGCGCAGCGGATCGCGCACCGCTTCGGGCTCAATTCGCAAAGCCTG
CCGAAGCCGCACAGCGCGTTCTCGAAGAACGGCTTCTTCCTGCGCGACCTGTTTTCGAAGGTGATCTTCGCCGATCGCCA
GACGGTCCGCCAGTTCGCGAGCCCGACGAAGACGCGCGTGCGCTACGCGACGTTCTTCGGCTTCGTCGCGGCGCTCGCGC
TCGCGCTCGGCGGCTGGACCTGGTCGACGATCGGCAACCAGCAACTCGTCTCGAACGTGCAGGCCGACCTCGACAACGTG
ACCCGCCTGCAGCAGAACCGCAACGATCTGCAATCTCGCCTGCAGGCGATGGACATCCTCGAGGATCGGATCGAGCAGCT
CGAGCAGTTCCGGCGCGACAAGCCGCTGTCCGTCTCGCTCGGCCTGTATCAGGGCAATCGGCTCGAGCAGCACCTGTTGA
CCGAGTACTACAACGGCGTGCGGCAGATCCTGCTCGCTCCCGTGTCGGACAATCTCGCGTCGTTCCTGAAGGACGTGAAC
GCGCATCCGGACCAGCTCGCGCCGATGACGCGCGCGCCCGAATCGGGCGCGACGCCGGCGGGCCCGATGCCGGTATCGAC
CCATCCCGCGGCGCCGGGCGCGGCCCCCTCCCCCGCCGTCGCGCAGGGCCGGCAGCAGGGCGGCCTCTATAACGACGCGT
CGCCGACCAACGTCGAGGACGCGTACAACGCGCTGAAGACCTACCTGATGCTCTCCGACAAGCGGCACGTCGAGCAGGCG
CACCTGACCGATCAGGTCGCGCGCTTCTGGCGCGGCTGGCTCGAGACGAATCGCGGCAACATGCCGCGCGACGAGATGAT
CAGGAGCGCGGAGCGAATGATCACCTTCTACCTGTCGCGCGTGTCCGACAACGACTGGCCGATGATCGAGGCAAATCTCG
CGCTCGTCGACCAGACCCGCGAGAACCTGCGCCGCGTCGTGCGCGGCATGCCGGCCCGCCAGCGCGTGTATGAAGAGATC
AAGGCGCGCGCGTCGACCCGCTTCGCGCCGATGACGATCGCGCGCATCGTCGGCGAAGGCAACACCGGCCTCGTCGCGGG
CAGCTACGCGATCCCCGGCACGTTCACGCGCGACGCGTGGTTCCAGTACGTGCAGCCGGCGATCCGCGACGCCGCGACGA
AGGAGCTGCAGGCGAAGGATTGGGTGCTGAACACCGCGTCGGCGGACGATCTGACGCTCGAGGGCAGCCCCGAGCAGATC
CAGAAGACGCTCGTCGCGATGTACAAGACCGAGTACGCGCAGCACTGGCAGAAGTTCATGCAGGGCATCGCGGTGCAGGG
CTTCGGCAATTTCACGCAGGCGGTCGACGCGATGAACAAGCTCGGCGATCCGCAGGATTCGCCGATCCGCAAGGTGCTCG
AGACCGCGTACGACCAGACCTCGTGGGACAACCCGTCGCTCGCGAACGCGACGATCAAGAAGGCGCAGACGGGCGTCGTG
AACTGGGTCAAGCAGTGGTTCACGCGCCAGCCGGGCGGCCAGATCGCGGCGAACGTCGACATCAACGGCAATCCCGCCGA
CGTGCCGATGGGCCCGATCGGCCAGGAGTTCGTCGGGCTCGGCCGGATCGTCGCCACGCACGACGGCACGTCGATGCTCA
AGGGCTACATGGACACGCTGTCGAAGGTCCGCACGCGCTTTAACGTGATCAAGAACCAGGGCGACCCCGGCCCCGGCGCG
CGTCAGCTGATGCAGCAAACGCTCGACGGCAACGGCTCGGAGCTCGCCGATTCGCTGAAGTTCGTCGACGAGCAGATGCT
CACGGGCTTGACCGATTCGCAACGCAAATCGCTGCGCCCGCTTCTCGTGCGCCCGCTGATGCAGGCGTTCGCGGTCGTGA
TCCAGCCGGCGAGCGTCGAGGTGAACAAGGTATGGAACGCGCAGGTGTACCAGCCGTTCCAGAACTCGCTCGCGAACAAG
TATCCGTTCGCGGCGGGCGCGAAGGTCGAGGCGGGCGCGGGCGAGATCGCGCAGGTGTTCGGCCCCGACGGCTCGATCGC
GAAGTTCGTCGGCACGACGCTCGGCCCGCTCGCGGTGCGCCGCGGCGACACGCTGTCCGCGCGCACCTGGGGCGACATGG
GCCTCGCGCTCACGCCGGACTTCACGGGCGGCTTCGCGCGCTGGGTCGCGCCGCTCGCGGGCGGCGCGGCGACGAGCGCG
GCCGCGTCGTCCGAGCCGCAGACCGTGTTCCAGGTGCTGCCGCAGCCGAGCAGCGGCACGACCGAATACACGATCGCGAT
CGACGGCCAGCAGCTGCGCTACCGCAACACGCCGCCGCAATGGACGAACTTCGTGTGGCCGAACCCGCAGGGCTCGCCCG
GCGCGACGCTGTCCGCGACGACCTTCGACGGCCGCACGTTGCAGCTCGTCAACGAGCCGGGCCGCTACGGCCTCGAGAAG
CTGATCAACTCGGCGCAGCGCAAGCGCCGTCCGGACGGCACGTTCGATCTGACATGGACGCAGGGCAGCGTCAGCGTCTC
GGTGACGATGCGCATCATCAGCACCTCGCAGCCGACGGGCGGCGGCGATCAGCCGCAGCAGCAAAGCCTGCGCGGCCTGC
GCCTGCCTTCGTCGGTCGCCGACGCGAGCGCGGGCGGCGCGGCCAATGCGACGGCGCAACCCGGCTCGGGCGCCGCGGCC
GCGCAGGTCGCCGCCACGGCCGCTTCCGCATCGAACGCACAGGGGGCGCAATGA