Detailed information of component protein


Summary

Component ID T6CP259522
Component protein type TssM
T6SS ID (Type) T6SS17503 experimental (Type i1)
Strain Aeromonas hydrophila strain NF1
Replicon chromosome
Sequence Protein sequence (1162 a.a.); Nucleotide sequence (3486 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) BE47_RS0109280
Coordinate (Strand) 55465..58950 (-)
NCBI ID WP_041213753.1
RefSeq NZ_JDWB01000021
Uniprot ID UPI00059CC44F
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 8.4e-74 502..815
IcmF-related_N PF14331.8 9.1e-73 201..450
IcmF_C PF06744.14 3.8e-22 1034..1141
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-19 MFKTIFTFLRQQLPKLKPS
Transmembrane helix 20-39 WPLLGAVLWVLALILVWWLG
Outside 40-53 PRLEVRDAKPFEPL
Transmembrane helix 54-76 WGRVVFTLLWLWLLLGVVSWRVW
Inside 77-445 RKMQQLKAERQHEVVLEQDPVKGLIDRQALFLDRWLQALNTHLGKGALYAMPWYLVLGLPGSGKSSLIHRANPANKLNPRLDTELRDVAQDQLVDCWLGEQAVMLDPAGVLLSQSEAELDPQARKHERLWLHLLGWLNEHRRRQPLNGLVLTVDLAWLSHASVAERKAYAQLMRSRLQEVSATMNTRLPLYVTFTKLDLLRGFEVIYQQLDKEAREAVLGVTFKPGADWQQDLAQFWDQWVDNLNQNLPELMLSRLDAAQRNALFSFVRQLAGLKDYVTSLLAETLAIEESKPLLVRGVYVSSVYQQGVPFDAFAQAASRRYNLPEPIHSALRGESNTYFVRQLFSSIIFPEAHLAGENRLHTLYRRRR
Transmembrane helix 446-468 MAIGLSCLSLFSAALIGGWHYFY
Outside 469-1161 RVNEEAGRNVLTKAQAFMETNEVADAHAFGVSQLPRLNLIREATLSFGNYRERMPLVADLGLYQGDEIGPYVEGSYLQLLSLRFLPAQMQGLLEDLNQAPAGSEEKLAILRVMRMLDDASGRNKELVAQYMASRWQKAFPGQGAVQEQLMGHLDYALDHTNWYGARAERDQAAITAFVPFKEPVYGAQRELGKLPMYQRVYQNLVVKAGDVLPPDLNVRDEVGPTFDTVFALRSDNAGQVPRLLTWPGFNDFFLKQDKALIDLTAMDAWVLGQRKLSQLSEADRKEITRQVNGRYVTDYVNQWQKLLTNLDVQTLESPEQALDVLAAITGNDQPFQRVLASLDDNTRIRKISDVEGDPAQAISARIGRPFMATNGVLAGRGEQGPLIQEVNQKLVELQHYLELIVNATEPGQSALKAVQLRMTNKYADPVFALQQYARSLPAPLDRWVGQLSEQSSRLVIDLAMSSLNQEWQDKVLAPFNSQLAGRYPFDPSSNKDVPLSEMERFFAPNGTLDSFYQVNLKPMVESGLMEGEFSSPIQAELVKQLDRAARIRQIFFSQQGNLEVQFALEPIELTANKRRSVLNLDGQLLEYAHGRRTKIPLVWPNTMRDGAESKITLVPAARERSPRSEGFVGPWAMFRLMDKGELTQVNDATFDVRFPVDQGAMTYRVYTDSAQNPFTGGLFSQFRLPESLY


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9950 - -


  Protein sequence: 1162 a.a.    

>T6CP259522 NZ_JDWB01000021:c58950-55465 [Aeromonas hydrophila] [TssM]
MFKTIFTFLRQQLPKLKPSWPLLGAVLWVLALILVWWLGPRLEVRDAKPFEPLWGRVVFTLLWLWLLLGVVSWRVWRKMQ
QLKAERQHEVVLEQDPVKGLIDRQALFLDRWLQALNTHLGKGALYAMPWYLVLGLPGSGKSSLIHRANPANKLNPRLDTE
LRDVAQDQLVDCWLGEQAVMLDPAGVLLSQSEAELDPQARKHERLWLHLLGWLNEHRRRQPLNGLVLTVDLAWLSHASVA
ERKAYAQLMRSRLQEVSATMNTRLPLYVTFTKLDLLRGFEVIYQQLDKEAREAVLGVTFKPGADWQQDLAQFWDQWVDNL
NQNLPELMLSRLDAAQRNALFSFVRQLAGLKDYVTSLLAETLAIEESKPLLVRGVYVSSVYQQGVPFDAFAQAASRRYNL
PEPIHSALRGESNTYFVRQLFSSIIFPEAHLAGENRLHTLYRRRRMAIGLSCLSLFSAALIGGWHYFYRVNEEAGRNVLT
KAQAFMETNEVADAHAFGVSQLPRLNLIREATLSFGNYRERMPLVADLGLYQGDEIGPYVEGSYLQLLSLRFLPAQMQGL
LEDLNQAPAGSEEKLAILRVMRMLDDASGRNKELVAQYMASRWQKAFPGQGAVQEQLMGHLDYALDHTNWYGARAERDQA
AITAFVPFKEPVYGAQRELGKLPMYQRVYQNLVVKAGDVLPPDLNVRDEVGPTFDTVFALRSDNAGQVPRLLTWPGFNDF
FLKQDKALIDLTAMDAWVLGQRKLSQLSEADRKEITRQVNGRYVTDYVNQWQKLLTNLDVQTLESPEQALDVLAAITGND
QPFQRVLASLDDNTRIRKISDVEGDPAQAISARIGRPFMATNGVLAGRGEQGPLIQEVNQKLVELQHYLELIVNATEPGQ
SALKAVQLRMTNKYADPVFALQQYARSLPAPLDRWVGQLSEQSSRLVIDLAMSSLNQEWQDKVLAPFNSQLAGRYPFDPS
SNKDVPLSEMERFFAPNGTLDSFYQVNLKPMVESGLMEGEFSSPIQAELVKQLDRAARIRQIFFSQQGNLEVQFALEPIE
LTANKRRSVLNLDGQLLEYAHGRRTKIPLVWPNTMRDGAESKITLVPAARERSPRSEGFVGPWAMFRLMDKGELTQVNDA
TFDVRFPVDQGAMTYRVYTDSAQNPFTGGLFSQFRLPESLY*

  Nucleotide sequence: 3486 bp    

>T6CP259522 NZ_JDWB01000021:c58950-55465 [Aeromonas hydrophila] [TssM]
ATGTTCAAAACCATTTTTACTTTTCTGCGGCAACAGCTGCCGAAATTGAAACCCTCCTGGCCCCTGCTCGGTGCTGTGCT
CTGGGTGCTGGCTCTCATTCTGGTGTGGTGGCTGGGCCCTCGTCTCGAGGTGCGCGACGCCAAGCCGTTCGAGCCGCTGT
GGGGGCGGGTGGTGTTCACCCTGCTCTGGCTCTGGTTGCTGCTGGGAGTGGTCTCCTGGCGGGTGTGGCGCAAGATGCAG
CAGCTCAAGGCCGAGCGCCAGCACGAGGTGGTGCTGGAGCAGGATCCGGTCAAGGGGCTCATCGACAGGCAGGCGCTGTT
CCTCGATCGCTGGCTGCAGGCGTTGAATACCCATCTGGGTAAGGGGGCGCTCTACGCCATGCCCTGGTATCTGGTGCTGG
GCCTGCCCGGCAGCGGCAAGAGCAGCCTCATTCACCGCGCCAACCCGGCCAACAAGCTCAACCCGAGACTCGACACCGAG
CTGCGCGACGTGGCGCAGGATCAGCTGGTGGATTGCTGGCTGGGGGAACAGGCCGTGATGCTGGACCCCGCCGGGGTGCT
GCTCTCCCAGAGCGAAGCCGAACTGGATCCGCAGGCCCGCAAGCATGAGCGGCTCTGGCTGCACCTGCTTGGCTGGCTCA
ATGAACACCGTCGTCGCCAGCCCCTCAACGGCCTGGTGCTGACCGTGGATCTGGCCTGGCTCTCCCACGCCAGCGTGGCT
GAGCGCAAGGCCTATGCCCAGCTGATGCGCTCGCGCCTGCAGGAGGTGTCGGCCACCATGAATACCCGGTTGCCGCTCTA
TGTCACCTTCACCAAGCTCGATCTGCTGCGCGGCTTTGAGGTGATCTACCAGCAGCTCGACAAGGAGGCCCGCGAGGCCG
TGTTGGGGGTGACCTTCAAGCCGGGTGCTGACTGGCAACAGGATCTGGCCCAGTTCTGGGATCAGTGGGTGGACAACCTC
AACCAGAATCTGCCCGAACTGATGCTGAGCCGGCTCGATGCCGCCCAGCGCAACGCGCTGTTCTCGTTCGTGCGCCAGCT
GGCGGGCCTCAAGGATTACGTGACCAGCCTGCTGGCCGAGACCCTGGCCATCGAGGAGAGCAAGCCGCTGCTGGTGCGCG
GGGTCTATGTCAGCTCCGTCTATCAGCAAGGGGTGCCGTTCGATGCGTTTGCCCAGGCGGCCTCCCGTCGCTACAACCTG
CCAGAGCCCATCCACTCGGCCCTGCGCGGGGAGTCCAACACCTATTTCGTGCGCCAGCTGTTCTCCTCCATCATCTTCCC
GGAGGCCCATCTGGCCGGCGAGAACCGGCTGCACACCCTCTATCGCCGGCGCCGCATGGCCATCGGTCTGAGCTGTCTGT
CGCTCTTCTCGGCCGCCCTCATCGGTGGCTGGCACTACTTCTACCGGGTCAACGAGGAGGCGGGTCGCAACGTATTGACC
AAGGCCCAGGCCTTCATGGAGACCAACGAGGTGGCCGACGCCCACGCCTTCGGGGTGAGCCAGCTGCCGCGCCTCAACCT
TATTCGCGAGGCGACCCTCTCCTTTGGCAACTACCGCGAGCGGATGCCGCTGGTGGCCGACCTCGGCCTCTACCAGGGGG
ACGAGATTGGTCCTTATGTGGAGGGCTCCTACCTACAACTGTTGAGCCTGCGCTTCCTGCCGGCCCAGATGCAGGGATTG
CTTGAGGATCTCAACCAGGCGCCTGCCGGCAGCGAGGAGAAGCTCGCCATCCTGCGGGTGATGCGGATGCTGGACGATGC
GTCCGGTCGCAACAAGGAGTTGGTGGCGCAGTACATGGCGAGCCGCTGGCAGAAGGCCTTCCCGGGACAGGGCGCGGTAC
AGGAGCAGCTGATGGGGCACCTGGACTATGCCCTCGACCACACCAACTGGTATGGCGCCAGGGCCGAGCGGGATCAGGCC
GCCATCACCGCCTTCGTGCCGTTCAAGGAGCCGGTCTACGGTGCCCAGCGCGAGCTCGGCAAGCTGCCCATGTATCAGCG
GGTCTACCAGAATCTGGTGGTGAAGGCGGGCGATGTATTGCCGCCGGATCTCAACGTGCGTGACGAGGTGGGCCCCACCT
TCGACACCGTGTTTGCCCTGCGCAGCGACAACGCCGGCCAGGTGCCGCGGCTGCTCACCTGGCCCGGTTTCAACGACTTC
TTCCTCAAGCAAGACAAGGCCCTCATCGATCTCACCGCGATGGATGCCTGGGTGCTGGGCCAGCGCAAGCTGAGCCAGCT
GAGCGAGGCGGATCGCAAGGAGATCACCCGTCAGGTCAATGGCCGCTACGTCACCGATTACGTCAACCAGTGGCAAAAAC
TGCTGACCAATCTGGACGTGCAGACCCTGGAGAGCCCGGAGCAGGCGCTGGACGTGCTTGCTGCCATCACCGGCAACGAT
CAGCCGTTCCAGCGGGTGCTGGCCTCGCTGGATGACAACACCCGCATTCGCAAGATCTCCGACGTGGAAGGGGACCCGGC
CCAGGCCATCAGCGCCCGCATCGGTCGACCCTTTATGGCCACTAATGGAGTATTGGCTGGCCGTGGCGAGCAGGGACCGC
TCATTCAGGAGGTCAACCAGAAGCTGGTGGAGCTGCAGCACTACCTGGAGCTCATCGTCAACGCCACCGAGCCGGGCCAG
TCTGCCTTGAAAGCGGTGCAGCTGCGCATGACCAACAAGTACGCCGATCCGGTGTTCGCCCTGCAGCAATATGCCCGCAG
TCTGCCGGCTCCGCTCGATCGCTGGGTGGGTCAGCTCTCCGAGCAGAGCTCGCGACTGGTGATCGATCTTGCCATGTCCT
CCCTCAATCAGGAGTGGCAGGACAAGGTGCTGGCCCCCTTCAACAGCCAGCTGGCCGGTCGTTATCCGTTTGATCCGAGC
TCGAACAAGGACGTGCCCCTCTCCGAGATGGAGCGCTTCTTCGCACCCAACGGGACGCTGGACAGCTTCTATCAGGTCAA
CCTCAAACCCATGGTGGAGAGCGGCCTGATGGAAGGGGAGTTCAGCTCGCCCATCCAGGCCGAGCTGGTCAAGCAGCTGG
ACCGTGCTGCCCGCATCCGTCAGATCTTCTTCAGCCAGCAGGGCAACCTGGAGGTGCAGTTTGCCCTCGAGCCCATCGAG
CTCACCGCCAACAAGCGGCGCAGTGTGCTGAACCTGGACGGCCAGCTGCTGGAATACGCCCATGGCCGTCGTACCAAGAT
CCCGTTGGTGTGGCCCAACACCATGCGCGACGGGGCCGAGAGCAAGATCACCCTGGTGCCGGCCGCCCGCGAGCGCTCAC
CGCGCAGCGAAGGCTTCGTCGGCCCCTGGGCCATGTTCCGCCTGATGGACAAGGGGGAGCTGACCCAGGTCAATGACGCC
ACCTTCGATGTGCGCTTCCCGGTGGATCAGGGGGCCATGACCTATCGCGTCTACACCGACAGTGCGCAAAACCCCTTCAC
CGGCGGCCTGTTCAGTCAGTTCAGACTGCCCGAATCCCTCTATTGA