SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP207890
Component protein type	TssB
T6SS ID (Type)	T6SS13923 (Type i3)
Strain	Enterobacter sp. DSM 30060
Replicon	chromosome
Sequence	Protein sequence (175 a.a.); Nucleotide sequence (525 bp)
Reference	[1] Flaugnatti N, Isaac S, Lemos Rocha LF, et al. Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms. Nat Commun. 2021 Oct 1;12(1):5751. doi: 10.1038/s41467-021-26041-0. PMID: 34599171

Experimental investigation has been performed on this T6SS

External database links

Locus tag (Gene)	HWQ15_RS21400
Coordinate (Strand)	4487681..4488205 (-)
NCBI ID	WP_022648413.1
RefSeq	NZ_CP056118
Uniprot ID	A0A330DH79_9ENTR, A0A4V1RH15_9ENTR, A0A4R0FMD1_9ENTR, A0A0F0NM60_ENTCL
KEGG ID	ecli:ECNIH5_12515
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
T6SS_VipA	PF05591.14	3e-58	12..161

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-174	MAMSNSGQKFIARNRAPRVQIEYDVEIYGAERKIQLPFVMGVMADLVGKPVENLPAVDERKFLEIDIDNFDERMKALKPRVAFQVDNTLTGEGKLNVDLTFDSMDDFLPDAVARKVEPLNKLLEARTQLSNLLTYMDGKNGAEELIAKILQDPTLLKSLSQMPKNDESAKGSEE

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9959	-	-

Protein sequence: 175 a.a.

						>T6CP207890 NZ_CP056118:c4488205-4487681 [Enterobacter sp. DSM 30060] [TssB]
MAMSNSGQKFIARNRAPRVQIEYDVEIYGAERKIQLPFVMGVMADLVGKPVENLPAVDERKFLEIDIDNFDERMKALKPR
VAFQVDNTLTGEGKLNVDLTFDSMDDFLPDAVARKVEPLNKLLEARTQLSNLLTYMDGKNGAEELIAKILQDPTLLKSLS
QMPKNDESAKGSEE*					

Nucleotide sequence: 525 bp

						>T6CP207890 NZ_CP056118:c4488205-4487681 [Enterobacter sp. DSM 30060] [TssB]
ATGGCAATGAGTAACAGTGGACAGAAATTCATCGCACGCAACCGTGCTCCCCGCGTGCAGATCGAATACGACGTAGAGAT
CTACGGCGCAGAACGCAAAATTCAGCTGCCGTTTGTGATGGGCGTTATGGCCGATCTGGTTGGCAAGCCGGTGGAAAACC
TGCCAGCCGTCGACGAGCGTAAGTTCCTTGAAATCGACATCGACAACTTCGACGAACGCATGAAGGCGCTGAAGCCGCGC
GTGGCGTTCCAGGTGGATAACACCCTGACCGGCGAAGGTAAGCTCAACGTCGATCTGACCTTTGACAGCATGGACGACTT
CCTGCCGGACGCGGTGGCCCGCAAGGTTGAGCCGCTGAACAAGCTACTGGAGGCTCGTACCCAGCTCTCTAACCTGTTGA
CCTACATGGACGGCAAAAACGGCGCGGAAGAGCTGATTGCAAAAATCCTTCAGGATCCGACGCTGCTCAAATCCCTGAGC
CAGATGCCAAAAAATGACGAAAGTGCGAAAGGTAGCGAGGAATAA					