SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP207887
Component protein type	TssD
T6SS ID (Type)	T6SS13923 (Type i3)
Strain	Enterobacter sp. DSM 30060
Replicon	chromosome
Sequence	Protein sequence (161 a.a.); Nucleotide sequence (483 bp)
Reference	[1] Flaugnatti N, Isaac S, Lemos Rocha LF, et al. Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms. Nat Commun. 2021 Oct 1;12(1):5751. doi: 10.1038/s41467-021-26041-0. PMID: 34599171

Experimental investigation has been performed on this T6SS

External database links

Locus tag (Gene)	HWQ15_RS21375
Coordinate (Strand)	4484078..4484560 (-)
NCBI ID	WP_014884229.1
RefSeq	NZ_CP056118
Uniprot ID	V3P3Q8_9ENTR, A0A4V3HB51_9ENTR, A0A145NSW9_9ENTR, A0A2W0G8U0_9ENTR, A0A2T9VCC0_9ENTR, A0A5Q5EMU3_9ENTR, A0A7U5VD76_9ENTR, A0A0F0XPU6_9ENTR, A0A0X4ED58_9ENTR, A0A5C1C0T4_9ENTR, A0A4Q2QXJ3_9ENTR, A0A4R0FL95_9ENTR, A0A6C2DMN1_9ENTR, W0BVZ5_9ENTR, A0A6N3H5I2_ENTAG, A0A0A6JJI6_ENTCL, A0A6L4XN73_ECOLX, A0A4Y8IQZ8_9ENTR
KEGG ID	elg:BH714_09190, eno:ECENHK_13195, ecli:ECNIH5_12490, ehm:AB284_12590, ecln:ECNIH4_09790, ekb:BFV64_13245, echg:FY206_14290
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
T6SS_HCP	PF05638.14	4.9e-37	6..131

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-160	MAIDMFLKVEGVTGESKDSNHTGWTDITSFSWGASQPGNMSVGGGGGAGKVNFNDLHVNALIDKSTTAILKHCASGKHLTKVELSVCKAGGQQVEYTRITLEDVLVTSVQYTGADNGDTVGVTYAFQAAKVKQQYWEQTTAGGKGAESSAGWNIKENKEA

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9458	-	-

Protein sequence: 161 a.a.

						>T6CP207887 NZ_CP056118:c4484560-4484078 [Enterobacter sp. DSM 30060] [TssD]
MAIDMFLKVEGVTGESKDSNHTGWTDITSFSWGASQPGNMSVGGGGGAGKVNFNDLHVNALIDKSTTAILKHCASGKHLT
KVELSVCKAGGQQVEYTRITLEDVLVTSVQYTGADNGDTVGVTYAFQAAKVKQQYWEQTTAGGKGAESSAGWNIKENKEA
*					

Nucleotide sequence: 483 bp

						>T6CP207887 NZ_CP056118:c4484560-4484078 [Enterobacter sp. DSM 30060] [TssD]
ATGGCTATTGATATGTTTCTGAAGGTCGAGGGTGTTACGGGCGAATCTAAAGATTCTAACCACACCGGCTGGACTGATAT
TACCTCCTTCTCCTGGGGCGCGTCCCAGCCGGGTAATATGAGCGTTGGTGGCGGCGGCGGTGCCGGTAAGGTTAACTTTA
ACGATCTGCACGTTAACGCTCTGATCGACAAATCCACTACAGCAATCCTGAAACACTGCGCAAGCGGTAAGCACCTGACC
AAAGTTGAACTGTCCGTCTGCAAAGCGGGTGGTCAGCAGGTTGAATATACCCGCATCACCCTGGAAGACGTTCTCGTGAC
TTCCGTTCAGTACACCGGTGCCGACAACGGCGATACCGTTGGCGTGACCTATGCATTCCAGGCTGCGAAAGTGAAACAGC
AGTACTGGGAGCAGACCACTGCCGGTGGTAAAGGTGCTGAAAGCAGCGCTGGCTGGAACATCAAAGAGAACAAAGAAGCG
TAA					