SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP207883
Component protein type	TssE
T6SS ID (Type)	T6SS13923 (Type i3)
Strain	Enterobacter sp. DSM 30060
Replicon	chromosome
Sequence	Protein sequence (188 a.a.); Nucleotide sequence (564 bp)
Reference	[1] Flaugnatti N, Isaac S, Lemos Rocha LF, et al. Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms. Nat Commun. 2021 Oct 1;12(1):5751. doi: 10.1038/s41467-021-26041-0. PMID: 34599171

Experimental investigation has been performed on this T6SS

External database links

Locus tag (Gene)	HWQ15_RS21340
Coordinate (Strand)	4477562..4478125 (-)
NCBI ID	WP_015570336.1
RefSeq	NZ_CP056118
Uniprot ID	A0A0A5SRG7_9ENTR, A0A4R0FN73_9ENTR, A0A2J7LP68_ENTCL, A0A6D0K9E1_ECOLX
KEGG ID	ecli:ECNIH5_12445, ehm:AB284_12625
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
GPW_gp25	PF04965.16	2.7e-20	59..163

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-187	MSNPAGEGDLLRSGWQARSRQEKVGARDKMQPSLLDRLTDNDPEKKRESANSNLITHAALRRNVLRDLQWLFNTINHDASSDLSGLTQVSRSVVNFGVAPLAGKRMSDIEWHDIQRKLTEAIINFEPRILPQGLQVRCVSDTSSLDLHNVLSIEIKGRLWCVPYPLEFLFRTDVDLENGHFELKDAG

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9871	-	-

Protein sequence: 188 a.a.

						>T6CP207883 NZ_CP056118:c4478125-4477562 [Enterobacter sp. DSM 30060] [TssE]
MSNPAGEGDLLRSGWQARSRQEKVGARDKMQPSLLDRLTDNDPEKKRESANSNLITHAALRRNVLRDLQWLFNTINHDAS
SDLSGLTQVSRSVVNFGVAPLAGKRMSDIEWHDIQRKLTEAIINFEPRILPQGLQVRCVSDTSSLDLHNVLSIEIKGRLW
CVPYPLEFLFRTDVDLENGHFELKDAG*					

Nucleotide sequence: 564 bp

						>T6CP207883 NZ_CP056118:c4478125-4477562 [Enterobacter sp. DSM 30060] [TssE]
ATGAGTAATCCCGCTGGCGAAGGCGATCTGCTGCGCAGCGGCTGGCAGGCCCGCAGCAGGCAGGAGAAAGTGGGGGCGCG
CGACAAAATGCAGCCGTCACTGCTGGATCGCCTGACGGATAACGATCCGGAAAAAAAACGCGAGTCCGCCAACAGTAATC
TGATTACCCACGCCGCGCTGCGTCGTAACGTCCTGCGGGATTTACAGTGGTTGTTTAACACCATTAACCACGATGCCTCC
AGCGATCTGAGTGGTCTGACGCAGGTGAGCCGTTCTGTCGTTAACTTTGGCGTCGCGCCGCTGGCGGGGAAAAGAATGTC
CGATATCGAATGGCACGACATTCAGCGCAAGCTCACCGAAGCGATTATTAACTTTGAACCGCGGATCCTGCCGCAGGGGC
TTCAGGTTCGCTGCGTGTCCGATACCTCCTCATTAGATCTGCACAACGTGCTGTCTATCGAAATCAAAGGCCGCCTGTGG
TGCGTACCGTATCCGCTGGAGTTTCTCTTTCGCACCGACGTCGATCTTGAGAACGGCCATTTTGAACTGAAGGATGCGGG
GTAA					