SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP207881
Component protein type	TssG
T6SS ID (Type)	T6SS13923 (Type i3)
Strain	Enterobacter sp. DSM 30060
Replicon	chromosome
Sequence	Protein sequence (348 a.a.); Nucleotide sequence (1044 bp)
Reference	[1] Flaugnatti N, Isaac S, Lemos Rocha LF, et al. Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms. Nat Commun. 2021 Oct 1;12(1):5751. doi: 10.1038/s41467-021-26041-0. PMID: 34599171

Experimental investigation has been performed on this T6SS

External database links

Locus tag (Gene)	HWQ15_RS21330
Coordinate (Strand)	4474648..4475691 (-)
NCBI ID	WP_022648402.1
RefSeq	NZ_CP056118
Uniprot ID	A0A155GFM8_9ENTR
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
T6SS_TssG	PF06996.13	6.5e-101	29..330

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-347	MSEVAPATLRVHRLTPLPDAFWRGVRETPWRYDLFQLLRRIDAQGGERYPLGRAPLPKFEPLRIGQQPSMGFAPSTVAEVRQREENGLHEVSILSFGLFGPNGPLPVHMTEYARERIHHHQDHSLSAFADLFHHRLTLLFYRAWADAQPAVSLDRDDNRRFEGYLASLIGMGQPGQMSKGSLSPHARFTHAGHLTRHGRDPEGLEKILRNYFNIPVRLVANVPQWMPLSTREQAQLGEGRRLPRMGESAFLGIAVRDVQHKFRLEIGPLSADEYNRFLPGEGWVTELRDWVRQYAGVEFEWETRVILRADAVQGTTLGSAGRLGYNTWLGLQPQPVPRGDLVYRAER

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9950	-	-

Protein sequence: 348 a.a.

						>T6CP207881 NZ_CP056118:c4475691-4474648 [Enterobacter sp. DSM 30060] [TssG]
MSEVAPATLRVHRLTPLPDAFWRGVRETPWRYDLFQLLRRIDAQGGERYPLGRAPLPKFEPLRIGQQPSMGFAPSTVAEV
RQREENGLHEVSILSFGLFGPNGPLPVHMTEYARERIHHHQDHSLSAFADLFHHRLTLLFYRAWADAQPAVSLDRDDNRR
FEGYLASLIGMGQPGQMSKGSLSPHARFTHAGHLTRHGRDPEGLEKILRNYFNIPVRLVANVPQWMPLSTREQAQLGEGR
RLPRMGESAFLGIAVRDVQHKFRLEIGPLSADEYNRFLPGEGWVTELRDWVRQYAGVEFEWETRVILRADAVQGTTLGSA
GRLGYNTWLGLQPQPVPRGDLVYRAER*					

Nucleotide sequence: 1044 bp

						>T6CP207881 NZ_CP056118:c4475691-4474648 [Enterobacter sp. DSM 30060] [TssG]
ATGAGTGAAGTTGCCCCTGCAACGCTGCGCGTGCATCGCCTGACGCCGCTGCCCGATGCGTTCTGGCGCGGAGTGCGCGA
GACGCCGTGGCGCTACGATCTGTTTCAGCTGTTAAGACGTATTGATGCCCAGGGCGGAGAACGTTACCCGCTGGGGCGCG
CGCCGCTGCCTAAATTTGAGCCGCTGCGTATTGGTCAGCAGCCTTCAATGGGGTTTGCGCCGTCAACGGTTGCCGAGGTC
CGGCAGCGGGAAGAGAACGGACTGCATGAGGTTTCCATTCTGAGCTTCGGCCTGTTTGGTCCTAACGGCCCACTGCCGGT
GCACATGACCGAGTATGCCCGCGAGCGTATTCATCATCATCAGGATCACAGCCTCAGCGCGTTTGCCGACCTCTTTCACC
ACCGCCTGACGCTGCTGTTTTACCGCGCCTGGGCGGACGCGCAGCCTGCCGTTTCACTGGATCGCGACGACAACAGGCGC
TTCGAAGGGTATCTTGCATCGCTGATTGGCATGGGTCAGCCCGGCCAGATGTCGAAAGGCAGCCTGAGCCCGCATGCCCG
CTTTACTCACGCCGGTCACCTGACCCGCCATGGGCGGGACCCGGAAGGGCTGGAGAAGATCCTGCGCAACTATTTCAACA
TTCCGGTCAGGTTGGTGGCCAATGTACCGCAGTGGATGCCGCTCTCAACGCGGGAGCAGGCACAGCTGGGTGAGGGGCGT
CGCCTGCCGCGCATGGGGGAGTCCGCTTTTCTCGGCATTGCGGTACGCGACGTGCAGCATAAATTTCGTCTTGAGATTGG
CCCGTTGAGCGCAGACGAATACAACCGTTTTCTGCCGGGTGAAGGGTGGGTCACCGAGCTGCGCGACTGGGTGCGACAGT
ACGCCGGGGTGGAATTTGAATGGGAAACACGGGTGATCCTGCGCGCCGATGCGGTGCAGGGCACCACGCTCGGCAGCGCC
GGGCGATTAGGGTACAACACCTGGCTGGGCCTTCAGCCTCAGCCTGTTCCGCGTGGCGATCTGGTGTATCGCGCAGAGCG
ATAA					