Detailed information of component protein


Summary

Component ID T6CP016010
Component protein type TssL
T6SS ID (Type) T6SS01290 experimental (Type i1)
Strain Vibrio cholerae DL4215
Replicon chromosome
Sequence Protein sequence (258 a.a.); Nucleotide sequence (774 bp)
Reference
experimental Experimental investigation has been performed on this T6SS

External database links

Locus tag (Gene) BL246_RS05960
Coordinate (Strand) 83065..83838 (+)
NCBI ID 446005552
RefSeq NZ_MOLM01000011
Uniprot ID D7HAU5_VIBCL, A0A023PTG4_VIBCL
KEGG ID vcx:VAA049_1793, vcz:VAB027_914
PDB ID -

Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
DotU PF09850.11 2.5e-61 39..240

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-219 MSQSKKETPLASLLFDDVEKINHDQDYWFQLRGDNPNVLIDAATPLFGLSLRVRTLTECDNIEQIYRQTIEEIKAIEIELTEQGYEHAILMAYRYILCAFLDESVMGTEWGASSLWAEHSMLSRFHNETWGGEKVFTILSRLEGEPHRYQALLAFIYHCLILGFEGKYRVMEGGQAEREKVISRLHQLLSSLEESEPQDLTRPTDHVVRAKYTLSRQMP
Transmembrane helix 220-242 VWSVFAGFIVLWIGLFLGYSYVL
Outside 243-257 HSKSSDVLNQLNQIL



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9933 - -



  Protein sequence: 258 a.a.    

>T6CP016010 NZ_MOLM01000011:83065-83838 [Vibrio cholerae] [TssL]
MSQSKKETPLASLLFDDVEKINHDQDYWFQLRGDNPNVLIDAATPLFGLSLRVRTLTECDNIEQIYRQTIEEIKAIEIEL
TEQGYEHAILMAYRYILCAFLDESVMGTEWGASSLWAEHSMLSRFHNETWGGEKVFTILSRLEGEPHRYQALLAFIYHCL
ILGFEGKYRVMEGGQAEREKVISRLHQLLSSLEESEPQDLTRPTDHVVRAKYTLSRQMPVWSVFAGFIVLWIGLFLGYSY
VLHSKSSDVLNQLNQIL*

  Nucleotide sequence: 774 bp    

>T6CP016010 NZ_MOLM01000011:83065-83838 [Vibrio cholerae] [TssL]
ATGTCACAGAGTAAAAAAGAGACGCCATTAGCCAGTTTGTTGTTCGACGATGTGGAAAAAATTAACCACGACCAAGACTA
CTGGTTCCAATTGCGTGGGGACAATCCGAATGTGCTGATTGATGCCGCGACACCCTTGTTTGGGCTTTCTCTGCGGGTTC
GCACCCTCACTGAATGCGACAACATTGAACAGATCTACCGTCAGACGATTGAAGAGATCAAAGCGATTGAAATTGAGTTG
ACGGAGCAAGGTTACGAACACGCCATTTTGATGGCCTATCGCTACATCTTGTGCGCCTTTTTGGATGAATCCGTGATGGG
AACCGAGTGGGGCGCGTCCAGTTTATGGGCCGAGCACTCCATGCTGTCACGTTTCCATAATGAAACGTGGGGCGGTGAGA
AAGTGTTTACGATTTTGAGCCGTCTTGAGGGTGAACCACACCGTTACCAAGCGCTATTGGCCTTTATTTATCACTGCCTG
ATTTTGGGCTTTGAAGGCAAATACCGTGTGATGGAAGGGGGACAAGCTGAGCGCGAAAAAGTGATCAGCCGCCTGCATCA
ACTGCTGAGCAGCTTGGAAGAGAGCGAGCCACAAGACTTAACCCGTCCGACCGATCATGTGGTGCGTGCGAAATATACCC
TAAGCAGACAGATGCCTGTTTGGTCTGTGTTTGCTGGCTTTATCGTGCTTTGGATAGGTCTATTTCTCGGCTACAGCTAT
GTGCTGCATAGCAAATCCAGCGATGTGCTCAATCAACTCAATCAAATACTTTAA