Detailed information of component protein


Summary

Component ID T6CP016005
Component protein type TssF
T6SS ID (Type) T6SS01290 experimental (Type i1)
Strain Vibrio cholerae DL4215
Replicon chromosome
Sequence Protein sequence (590 a.a.); Nucleotide sequence (1770 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) BL246_RS05935
Coordinate (Strand) 77006..78775 (+)
NCBI ID 446111937
RefSeq NZ_MOLM01000011
Uniprot ID Q9KN55_VIBCH, A0A0X1L1S3_VIBCO, A0A0H3AGM9_VIBC3, A0A0K9UV54_VIBCL, A0A0H3Q6K7_VIBCL, C3LUD4_VIBCM, A0A023PSA3_VIBCL
KEGG ID vch:VCA0110, vcq:EN18_04275, vcz:VAB027_919, vco:VC0395_0028, vcx:VAA049_1798, vcm:VCM66_A0108
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
T6SS_TssF PF05947.14 3.6e-158 5..584
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-589 MTQDKYFREELAFLKEQGKEFTEIHPQLSRFLHGRTTDPDVERLLEGFAFLTARLREKVEDEFPELTHSIINMLWPNYLRPIPSMSVVAFEPDKSVSEKQVIPRNTQLDSKPVFGTACHFNTCRDVALYPMQCQGVHAEHTREATTIQISLRMLGDMTVGDAKLDTVRFYLGGDKYSSQTLYLWLHHYLQKMTIEVQGVEFALPADAFSTVGFSSDQALLPYPKNVYDGYRILQEYLSFPEAFHFFDVKGFAKALPKAVSGDFTLRIHFSKTLPADTRVRQDNFQLYCTPVINLFEHDADPIDLTGRRSEYRIVPSSRYPAHYEIFSVDQVVGWQDTQSEGKRIRGEKRIYSSFESFQHEVERVRHRQALYYRTRVKESIRGDGFDSFISFVRGDETLSMGVDEAVSIKLTCTNRLLPLELGVGDICVATDSSPPFATFKNITVPSQSLRPVLDGSLLWTLISNLSLNYLSLLSKDALSCVLRAYDFRALVDRQAERVARMRLDGIVKIESKPVDKILRGLPVRGLQSTLYVDQAGFGSEGDLFLFGTVLSHFFALYASINSFHELVVVNISNQEKYSWGTQSGMQPLI


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9926 - -


  Protein sequence: 590 a.a.    

>T6CP016005 NZ_MOLM01000011:77006-78775 [Vibrio cholerae] [TssF]
MTQDKYFREELAFLKEQGKEFTEIHPQLSRFLHGRTTDPDVERLLEGFAFLTARLREKVEDEFPELTHSIINMLWPNYLR
PIPSMSVVAFEPDKSVSEKQVIPRNTQLDSKPVFGTACHFNTCRDVALYPMQCQGVHAEHTREATTIQISLRMLGDMTVG
DAKLDTVRFYLGGDKYSSQTLYLWLHHYLQKMTIEVQGVEFALPADAFSTVGFSSDQALLPYPKNVYDGYRILQEYLSFP
EAFHFFDVKGFAKALPKAVSGDFTLRIHFSKTLPADTRVRQDNFQLYCTPVINLFEHDADPIDLTGRRSEYRIVPSSRYP
AHYEIFSVDQVVGWQDTQSEGKRIRGEKRIYSSFESFQHEVERVRHRQALYYRTRVKESIRGDGFDSFISFVRGDETLSM
GVDEAVSIKLTCTNRLLPLELGVGDICVATDSSPPFATFKNITVPSQSLRPVLDGSLLWTLISNLSLNYLSLLSKDALSC
VLRAYDFRALVDRQAERVARMRLDGIVKIESKPVDKILRGLPVRGLQSTLYVDQAGFGSEGDLFLFGTVLSHFFALYASI
NSFHELVVVNISNQEKYSWGTQSGMQPLI*

  Nucleotide sequence: 1770 bp    

>T6CP016005 NZ_MOLM01000011:77006-78775 [Vibrio cholerae] [TssF]
ATGACGCAAGACAAGTATTTCAGGGAAGAGCTCGCTTTTTTAAAAGAGCAGGGGAAAGAATTTACCGAAATTCACCCTCA
GCTTTCGCGTTTTCTTCATGGCCGTACGACCGATCCTGACGTTGAGCGTCTTTTGGAAGGTTTTGCATTTCTTACCGCGC
GTTTGCGCGAAAAGGTGGAGGATGAGTTCCCTGAACTTACTCACTCCATCATTAACATGCTGTGGCCAAATTATCTGCGC
CCTATCCCGAGCATGAGTGTGGTGGCGTTTGAACCTGACAAAAGTGTCAGCGAGAAGCAAGTCATCCCACGTAATACCCA
ATTGGATAGCAAGCCAGTCTTTGGCACGGCGTGTCATTTCAACACTTGCCGTGATGTCGCGCTATATCCGATGCAGTGTC
AAGGTGTTCATGCCGAACACACACGTGAAGCCACGACCATTCAGATCTCGTTGCGCATGCTGGGCGATATGACAGTAGGC
GACGCTAAGCTCGATACCGTACGTTTTTACTTAGGTGGTGATAAATACAGCTCGCAGACTCTCTATCTTTGGTTACACCA
TTATCTACAAAAAATGACCATTGAAGTGCAGGGTGTCGAGTTCGCACTGCCTGCTGATGCGTTTTCAACCGTCGGTTTCT
CAAGTGACCAAGCCTTGCTGCCTTATCCAAAGAATGTCTATGACGGTTATCGTATTTTGCAAGAGTACCTGTCGTTTCCT
GAAGCCTTTCACTTCTTTGATGTAAAAGGTTTTGCCAAAGCGTTACCGAAAGCGGTCAGCGGTGATTTCACCTTACGCAT
CCATTTTTCGAAAACATTGCCTGCTGATACGCGAGTGCGTCAGGACAATTTTCAACTCTATTGCACGCCGGTCATCAATC
TGTTTGAGCATGATGCCGATCCGATCGATTTGACTGGGCGTCGTTCAGAGTATCGAATCGTCCCGTCCAGTCGCTATCCT
GCCCACTATGAAATTTTCAGCGTGGATCAAGTGGTTGGTTGGCAAGATACCCAGTCAGAAGGCAAACGGATCCGCGGAGA
AAAGCGGATCTACTCTTCTTTTGAAAGCTTCCAACATGAAGTGGAACGGGTTCGTCATCGTCAAGCGCTTTACTATCGCA
CACGAGTCAAAGAGAGCATCCGGGGGGATGGTTTTGATTCATTTATCTCTTTTGTGCGCGGTGATGAAACCTTATCAATG
GGCGTGGATGAAGCCGTCTCAATCAAACTCACCTGCACCAATCGCTTGCTGCCATTGGAACTTGGGGTGGGGGATATTTG
TGTGGCGACCGACAGCTCACCCCCTTTTGCCACATTTAAAAATATTACGGTGCCTTCGCAGTCACTGCGCCCGGTTCTCG
ATGGCAGCTTACTGTGGACGCTGATCTCGAATCTATCGCTGAACTACCTATCACTGCTTTCAAAAGATGCACTGAGCTGT
GTGCTACGCGCTTACGATTTTCGCGCCTTGGTCGATAGGCAAGCTGAACGTGTCGCACGGATGCGCCTTGATGGCATAGT
CAAAATAGAATCTAAACCGGTTGATAAAATCCTACGTGGTTTGCCTGTGCGTGGTTTGCAATCGACTTTGTATGTCGATC
AAGCGGGATTTGGCTCGGAAGGTGATTTGTTCCTGTTTGGTACGGTACTCAGTCATTTCTTTGCACTTTACGCCAGCATC
AACTCATTTCACGAATTAGTCGTGGTTAACATCAGCAATCAAGAGAAGTACTCATGGGGCACACAGAGCGGAATGCAGCC
GTTGATCTGA