SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP015748
Component protein type	TssD
T6SS ID (Type)	T6SS01264 (Type i3)
Strain	Serratia marcescens RM66262
Replicon	chromosome
Sequence	Protein sequence (161 a.a.); Nucleotide sequence (483 bp)
Reference	[1] Lazzaro M, Feldman MF, García Véscovi E. A Transcriptional Regulatory Mechanism Finely Tunes the Firing of Type VI Secretion System in Response to Bacterial Enemies. mBio. 2017 Aug 22;8(4). pii: e00559-17. doi: 10.1128/mBio.00559-17. PMID: 28830939

Experimental investigation has been performed on this T6SS

External database links

Locus tag (Gene)	RT90_RS02675
Coordinate (Strand)	579969..580451 (-)
NCBI ID	491099772
RefSeq	NZ_JWLO01000001
Uniprot ID	A0A2S4XAN8_SERMA, D4E4R4_SEROD
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
T6SS_HCP	PF05638.14	3.4e-37	6..131

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-160	MAIDMFLKVEGASGESKDSNHKGWTDITSFSWGASQPGNMGVGGGGGAGKVCFNDLHVNALVDKSTPALLKHCSSGKHLTKVELSVCKAGGTQVEYVKITLDDVLVTAVQYTGAGGEDTVGVTYSFQAAKVKQQYWEQSDKGGKGAESSAGWNIKENREA

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9102	-	-

Protein sequence: 161 a.a.

						>T6CP015748 NZ_JWLO01000001:c580451-579969 [Serratia marcescens] [TssD]
MAIDMFLKVEGASGESKDSNHKGWTDITSFSWGASQPGNMGVGGGGGAGKVCFNDLHVNALVDKSTPALLKHCSSGKHLT
KVELSVCKAGGTQVEYVKITLDDVLVTAVQYTGAGGEDTVGVTYSFQAAKVKQQYWEQSDKGGKGAESSAGWNIKENREA
*					

Nucleotide sequence: 483 bp

						>T6CP015748 NZ_JWLO01000001:c580451-579969 [Serratia marcescens] [TssD]
ATGGCTATCGATATGTTCCTGAAAGTTGAAGGTGCCAGCGGCGAATCTAAAGATTCGAATCACAAAGGCTGGACCGACAT
TACTTCTTTCTCCTGGGGCGCTTCTCAACCGGGCAATATGGGCGTTGGCGGCGGCGGTGGCGCCGGTAAAGTGTGCTTCA
ACGATCTGCACGTTAACGCGCTGGTCGACAAGTCAACCCCGGCGCTGCTGAAGCATTGCTCCAGCGGTAAGCACCTGACC
AAGGTTGAGTTGTCTGTCTGCAAGGCGGGCGGTACTCAGGTTGAGTACGTTAAAATCACCCTGGACGACGTGCTGGTCAC
CGCCGTGCAGTACACCGGCGCAGGCGGCGAAGACACCGTGGGCGTCACCTACTCCTTCCAGGCGGCGAAAGTGAAACAGC
AATACTGGGAGCAGAGCGACAAAGGCGGCAAAGGCGCCGAAAGCAGCGCAGGTTGGAACATCAAGGAAAACCGCGAAGCT
TAA					