Detailed information of component protein


Summary

Component ID T6CP015532
Component protein type TssM
T6SS ID (Type) T6SS01236 experimental (Type i5)
Strain Vibrio vulnificus 106-2A
Replicon chromosome
Sequence Protein sequence (1175 a.a.); Nucleotide sequence (3525 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) VV1062A_RS02945
Coordinate (Strand) 446966..450490 (-)
NCBI ID 782722905
RefSeq NZ_LMTD01000002
Uniprot ID UPI0005F24C70
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related_N PF14331.8 5.4e-88 194..451
IcmF-related PF06761.14 2.3e-67 506..804
IcmF_C PF06744.14 1.2e-17 1051..1152
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-15 MQTMAKIKRLLGQKW
Transmembrane helix 16-38 LISLIGLGAISIFIWFVGPLIAI
Outside 39-47 AGIEPLKSD
Transmembrane helix 48-67 FNRLLVIVVLVFIWGVTNVV
Inside 68-446 RQQKERKEQDESIQSLLEVDALTDKEAAAEIDVMRERIEKAIQVVTKGGKRKSHLYELPWYVLIGPPGTGKTTALKESGLEFPLSDSMGVDSVSGIGGTRNCDWWFTNKAVLIDTAGRYTTQDSQAHVDSKAWYGFLGLLKQYRKQRPINGAIVTVSIASMLTQTRTERGMHARAIKNRLQELKNQLGMQFPIYVVLTKADLIAGFSEFFTELTKEEREQLLGFMFPPSTEDERGVISLFNKEFHDLLERLDRRMMQRLETEHDLDKRSLIFEFPKQLRCLQANLDEFLNDIFAQNKFEESSMIRGVFIVSSLQEGTPVDRIMSETSQGLGLGKPLLRLSSKESSSYFVKNLFENVIFKEQFLGTVNRHHQKQSGWIRK
Transmembrane helix 447-469 GVYCSCMALSGAAITLWMMSYQW
Outside 470-1174 NNQLIDETDRQVTVVNDLLAKSGLDFENDLIPSINILNHIMRFPMGYRQQDDERDRVTSFGFFQGEKIGQSAKSAYHQALTNYYSSYVESVLLSEMKNNEQHREYLYETLKTYLMLFNDDKFEREHVLGWFNYFFERQYPGELNEELREQLYAHTENFLSQADRGLYINNDSVTAARLVLTEMSLSERAYQRMKLQFLKSHVPSFRLTDVLGARGVEQFERKSGKPLSMGISGFYTYNGFHSIFQLQLGRMVKALMEENWVYGDEIDAQNIDNDLALQGVRERYYRDYVYEWKTLLNDIQLKAAPSLKLSLEQSMTLAGSERPIESLLKAVQKEVALTKISLSNNEKAAAEVAGKVAKVKFSNTADKLDLYRPEEGNTFDIALPGKEVEAEFDDLVRMTDQDFDDIHLALSGLKSYLADLSSSGNNQKVAYKSILNGTVTGEVAASIEHAKQLLPAPFNNWLGELSEESVKLAEKGSRSHLNTLWVNKVLKPYERSIKGRYPFEPRAKTEVTLKDFSRFFGYGGTLDAFFVEYLEPFVDTSRSVWRFEKEIGVSQETLAVFQRADRIRQSFFELDNTLKVDFAMKPIYLDQHITSFVLEVGGQNLAYRHGPARVKNLSWPAKRSATRVVFTPPDSIREIAYTYEGEWGIFKLLDQSLKARPQSRKDNIVMIDLKGNKVQLELIPKSTMNPFWSSDMESFRCPQTL


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9952 - -


  Protein sequence: 1175 a.a.    

>T6CP015532 NZ_LMTD01000002:c450490-446966 [Vibrio vulnificus] [TssM]
MQTMAKIKRLLGQKWLISLIGLGAISIFIWFVGPLIAIAGIEPLKSDFNRLLVIVVLVFIWGVTNVVRQQKERKEQDESI
QSLLEVDALTDKEAAAEIDVMRERIEKAIQVVTKGGKRKSHLYELPWYVLIGPPGTGKTTALKESGLEFPLSDSMGVDSV
SGIGGTRNCDWWFTNKAVLIDTAGRYTTQDSQAHVDSKAWYGFLGLLKQYRKQRPINGAIVTVSIASMLTQTRTERGMHA
RAIKNRLQELKNQLGMQFPIYVVLTKADLIAGFSEFFTELTKEEREQLLGFMFPPSTEDERGVISLFNKEFHDLLERLDR
RMMQRLETEHDLDKRSLIFEFPKQLRCLQANLDEFLNDIFAQNKFEESSMIRGVFIVSSLQEGTPVDRIMSETSQGLGLG
KPLLRLSSKESSSYFVKNLFENVIFKEQFLGTVNRHHQKQSGWIRKGVYCSCMALSGAAITLWMMSYQWNNQLIDETDRQ
VTVVNDLLAKSGLDFENDLIPSINILNHIMRFPMGYRQQDDERDRVTSFGFFQGEKIGQSAKSAYHQALTNYYSSYVESV
LLSEMKNNEQHREYLYETLKTYLMLFNDDKFEREHVLGWFNYFFERQYPGELNEELREQLYAHTENFLSQADRGLYINND
SVTAARLVLTEMSLSERAYQRMKLQFLKSHVPSFRLTDVLGARGVEQFERKSGKPLSMGISGFYTYNGFHSIFQLQLGRM
VKALMEENWVYGDEIDAQNIDNDLALQGVRERYYRDYVYEWKTLLNDIQLKAAPSLKLSLEQSMTLAGSERPIESLLKAV
QKEVALTKISLSNNEKAAAEVAGKVAKVKFSNTADKLDLYRPEEGNTFDIALPGKEVEAEFDDLVRMTDQDFDDIHLALS
GLKSYLADLSSSGNNQKVAYKSILNGTVTGEVAASIEHAKQLLPAPFNNWLGELSEESVKLAEKGSRSHLNTLWVNKVLK
PYERSIKGRYPFEPRAKTEVTLKDFSRFFGYGGTLDAFFVEYLEPFVDTSRSVWRFEKEIGVSQETLAVFQRADRIRQSF
FELDNTLKVDFAMKPIYLDQHITSFVLEVGGQNLAYRHGPARVKNLSWPAKRSATRVVFTPPDSIREIAYTYEGEWGIFK
LLDQSLKARPQSRKDNIVMIDLKGNKVQLELIPKSTMNPFWSSDMESFRCPQTL*

  Nucleotide sequence: 3525 bp    

>T6CP015532 NZ_LMTD01000002:c450490-446966 [Vibrio vulnificus] [TssM]
ATGCAAACAATGGCAAAGATTAAACGTTTATTGGGGCAAAAATGGCTGATTAGCTTGATCGGGCTTGGGGCAATTTCTAT
TTTTATTTGGTTTGTCGGACCATTGATCGCGATAGCAGGCATAGAGCCACTGAAATCTGACTTTAACCGTTTGTTGGTTA
TTGTGGTTTTAGTCTTCATTTGGGGCGTGACGAATGTTGTCCGTCAACAGAAGGAGCGAAAGGAACAAGATGAAAGCATC
CAAAGCCTATTAGAGGTGGATGCCCTGACCGATAAAGAAGCGGCGGCAGAAATAGACGTCATGCGCGAAAGAATTGAGAA
GGCGATTCAAGTCGTGACGAAAGGTGGAAAGCGTAAGAGTCATCTCTACGAGTTGCCTTGGTATGTACTTATTGGTCCTC
CTGGAACAGGTAAAACGACGGCATTAAAAGAATCGGGTCTCGAGTTTCCTCTATCAGATTCAATGGGTGTTGACTCGGTT
TCTGGTATTGGCGGTACGAGAAATTGTGATTGGTGGTTTACCAATAAAGCGGTGTTGATTGATACGGCTGGCCGATACAC
CACGCAAGACAGCCAAGCTCATGTCGATTCAAAAGCATGGTATGGATTCTTAGGCTTATTGAAGCAATACCGTAAACAGC
GTCCTATTAATGGTGCGATTGTTACCGTCAGCATCGCAAGTATGCTCACACAAACTCGCACCGAACGAGGCATGCATGCA
AGAGCGATAAAAAATCGGCTACAAGAACTGAAAAATCAATTGGGTATGCAGTTCCCAATCTACGTTGTGTTGACTAAGGC
TGATCTCATTGCTGGTTTTAGTGAGTTTTTTACGGAACTGACCAAGGAAGAGCGTGAGCAGTTATTAGGTTTTATGTTTC
CACCTTCAACAGAAGACGAGCGAGGCGTCATCTCTCTATTTAACAAAGAGTTTCATGACTTACTGGAGAGACTTGATCGC
CGCATGATGCAAAGGCTTGAAACGGAGCATGACCTTGACAAACGATCTTTAATTTTTGAATTTCCAAAACAATTGCGTTG
TCTTCAAGCGAATCTAGACGAGTTTCTGAACGACATTTTTGCCCAAAACAAGTTTGAAGAATCTTCAATGATTCGCGGCG
TCTTTATTGTGAGTTCATTGCAAGAAGGCACGCCGGTTGATCGTATTATGTCTGAAACATCCCAAGGGCTGGGGTTGGGC
AAACCTCTACTGCGGTTAAGTTCCAAAGAATCAAGCAGCTATTTTGTAAAAAACTTGTTTGAAAACGTCATCTTTAAAGA
ACAGTTTTTAGGGACGGTCAATCGTCATCATCAAAAGCAAAGTGGCTGGATTCGAAAAGGCGTCTACTGCTCGTGCATGG
CACTGTCTGGGGCTGCGATCACACTGTGGATGATGAGTTATCAGTGGAACAATCAACTCATTGATGAAACGGATCGTCAA
GTGACTGTGGTGAATGACTTACTTGCTAAGTCTGGTCTGGACTTCGAAAACGACTTGATCCCCTCGATAAACATTCTCAA
TCACATCATGCGTTTCCCTATGGGTTATAGACAGCAAGATGACGAGAGAGATCGTGTGACATCGTTTGGTTTTTTTCAAG
GTGAAAAAATTGGCCAATCAGCGAAGAGTGCTTATCACCAAGCACTGACAAATTACTATTCATCCTATGTTGAATCGGTA
CTTCTCAGTGAAATGAAGAACAATGAACAACACCGAGAATATTTGTACGAAACACTCAAAACATATTTGATGCTTTTCAA
CGATGATAAATTTGAGCGTGAACATGTTCTTGGTTGGTTCAATTATTTCTTTGAAAGGCAGTATCCCGGCGAATTGAATG
AAGAGTTAAGAGAGCAACTCTACGCTCATACCGAAAACTTTTTGTCGCAGGCAGACAGAGGCTTATATATCAACAACGAT
TCAGTAACCGCTGCCAGATTGGTTCTAACAGAAATGTCGTTGTCGGAAAGGGCTTACCAAAGAATGAAACTGCAGTTCCT
TAAAAGTCATGTGCCTTCATTCCGTTTAACGGACGTTCTAGGGGCTAGGGGAGTTGAGCAGTTTGAGCGAAAAAGTGGCA
AGCCATTATCGATGGGGATTTCCGGTTTCTACACGTACAACGGTTTCCATAGCATCTTCCAATTGCAACTGGGTCGTATG
GTAAAAGCCTTGATGGAAGAAAACTGGGTGTATGGGGATGAGATTGACGCCCAAAACATCGACAATGATCTCGCTTTGCA
AGGTGTGAGAGAGCGCTACTATCGTGACTATGTCTATGAATGGAAGACACTGCTCAATGATATCCAACTCAAAGCGGCAC
CCAGTTTGAAACTAAGTTTAGAGCAGAGTATGACATTAGCGGGCTCTGAGCGACCAATTGAATCGCTGCTTAAAGCGGTA
CAAAAAGAGGTGGCATTAACGAAAATTTCGCTAAGCAACAACGAAAAAGCGGCAGCAGAAGTCGCTGGTAAAGTTGCCAA
AGTAAAATTTTCAAATACGGCGGACAAACTTGATTTATATCGTCCGGAAGAGGGCAATACGTTTGATATTGCGCTTCCTG
GAAAAGAAGTGGAAGCCGAGTTTGACGATCTTGTTAGGATGACAGACCAAGACTTTGACGATATTCATCTCGCACTGAGC
GGTTTAAAAAGTTATTTGGCCGATCTCTCTAGCTCAGGAAATAATCAGAAAGTCGCCTACAAGAGCATCTTAAATGGCAC
CGTGACAGGAGAAGTTGCCGCGTCAATTGAACATGCTAAACAGCTTTTACCCGCTCCGTTTAACAACTGGCTAGGTGAAC
TTTCCGAGGAATCGGTCAAGTTAGCGGAAAAAGGATCGCGATCTCACCTTAATACGCTATGGGTTAACAAGGTTCTTAAA
CCTTATGAGCGCAGCATCAAAGGCAGGTATCCGTTTGAGCCAAGAGCGAAAACAGAAGTGACGTTAAAGGACTTCAGTCG
ATTCTTTGGCTACGGCGGAACACTTGATGCGTTCTTTGTCGAATACTTGGAACCGTTTGTCGATACGTCGAGAAGTGTGT
GGCGCTTCGAGAAGGAAATCGGTGTCAGTCAAGAAACCCTCGCCGTATTTCAACGCGCAGATCGCATCCGACAATCGTTT
TTCGAACTCGACAATACACTAAAAGTCGATTTTGCAATGAAACCGATATACCTCGACCAACATATAACCAGTTTTGTACT
GGAAGTCGGGGGGCAGAATCTTGCATACCGACATGGGCCGGCAAGAGTAAAAAATCTGTCTTGGCCAGCTAAGCGTTCAG
CGACAAGAGTGGTCTTCACACCACCTGATTCGATTCGTGAAATTGCTTATACCTATGAGGGCGAATGGGGCATTTTTAAG
TTGCTTGATCAATCTCTGAAAGCAAGGCCGCAATCTCGCAAAGACAATATCGTCATGATTGATTTGAAAGGCAACAAAGT
TCAACTGGAATTGATTCCTAAAAGTACGATGAACCCATTTTGGTCGAGTGATATGGAGAGTTTCCGATGTCCGCAAACGC
TATAA