Detailed information of component protein


Summary

Component ID T6CP015383
Component protein type TssI
T6SS ID (Type) T6SS01216 experimental (Type Unknown)
Strain Klebsiella pneumoniae strain Kp52.145
Replicon chromosome
Sequence Protein sequence (900 a.a.); Nucleotide sequence (2700 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) BN49_RS18800
Coordinate (Strand) 3498991..3501690 (-)
NCBI ID WP_046043552.1
RefSeq NZ_FO834906
Uniprot ID W9BAA4_KLEPN
KEGG ID kpnk:BN49_3373
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Phage_GPD PF05954.13 2.7e-67 35..355
DUF2345 PF10106.11 9.2e-49 612..759
T6SS_Vgr PF13296.8 1.7e-33 491..592
Phage_base_V PF04717.14 7.9e-07 405..472
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-899 MDTSSIITGTTLNRYQLDIPSCAASLDVEEFSGAEKLSELYYYTITFTSAEKNIDAAQLLSKPAMLTMGGGALQQLADCKRVHGVITTFRRVNRSEDQSTYQITLQPFLSLLDKQFRSHRFFVNKSVPEVVEQVLQEHHLHDWEYEFNLKQHYPRREQINQYQESDLAFIQRLLAEVGIFYFFTLQEEAQSEVVHFADAQRALMFDKTLPVNSPSGMSDSGAESIWGLSITHNVVEANVTTRDYNPRDAQSVLQSATADMTRGNGEGITYGEVYHYKLRHRERGDKIEPQTETANFYARLDHERFLAHQTLITASSTAAWLAPAQVLTVTDSLPSTLPAPVQDPLLITGTGFTASRREALRVSLLAVPYSETLCWRPPLLPRPKVTGTMTARVTSAKANDIYAWQDASGLYRVKFDADRDEKGQGQESMPVRLAKPYGGDVYGFHFPLIQGTEVAIAFHEGDPDRPYIAHALHDSRHVDPVTEKNSTRNVIRTPANNKLRMEDKRGEEHIKLSTDYGGKTQLNLGHNVNAQRELRGEGFELRTDKWGAIRAGKGIFITADKQSTASGKILAMQDTLDRLKQAGDEMDSLSRDAQSAKADPAQVEQQLAFMREQIDQLREAVAVLSAPNGVALASGKHLQLTARRNLMLNAGADADMGVMKRLFIGVGEGLSLFVRKLGMKLIANQGPVAIQAQNDQLQLLARKELEIVSTDSEIHIVAKKKIIINAGGSYITLDPYRIELGTGGDVDVKAADFSYSGPASMKADHPDYPPLQSTVRQSLKLNVAQSPNASDSSWAGMPYTLYADGALLKQGVLDERGQISVDHQVVTRSYKLEMANGVSYQIPVAEAYSRPEQGELANRGFHHHTSQAASDINPPSSHTEHRNTYADLLDGHIEQDESQ


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9841 - -


  Protein sequence: 900 a.a.    

>T6CP015383 NZ_FO834906:c3501690-3498991 [Klebsiella pneumoniae] [TssI]
MDTSSIITGTTLNRYQLDIPSCAASLDVEEFSGAEKLSELYYYTITFTSAEKNIDAAQLLSKPAMLTMGGGALQQLADCK
RVHGVITTFRRVNRSEDQSTYQITLQPFLSLLDKQFRSHRFFVNKSVPEVVEQVLQEHHLHDWEYEFNLKQHYPRREQIN
QYQESDLAFIQRLLAEVGIFYFFTLQEEAQSEVVHFADAQRALMFDKTLPVNSPSGMSDSGAESIWGLSITHNVVEANVT
TRDYNPRDAQSVLQSATADMTRGNGEGITYGEVYHYKLRHRERGDKIEPQTETANFYARLDHERFLAHQTLITASSTAAW
LAPAQVLTVTDSLPSTLPAPVQDPLLITGTGFTASRREALRVSLLAVPYSETLCWRPPLLPRPKVTGTMTARVTSAKAND
IYAWQDASGLYRVKFDADRDEKGQGQESMPVRLAKPYGGDVYGFHFPLIQGTEVAIAFHEGDPDRPYIAHALHDSRHVDP
VTEKNSTRNVIRTPANNKLRMEDKRGEEHIKLSTDYGGKTQLNLGHNVNAQRELRGEGFELRTDKWGAIRAGKGIFITAD
KQSTASGKILAMQDTLDRLKQAGDEMDSLSRDAQSAKADPAQVEQQLAFMREQIDQLREAVAVLSAPNGVALASGKHLQL
TARRNLMLNAGADADMGVMKRLFIGVGEGLSLFVRKLGMKLIANQGPVAIQAQNDQLQLLARKELEIVSTDSEIHIVAKK
KIIINAGGSYITLDPYRIELGTGGDVDVKAADFSYSGPASMKADHPDYPPLQSTVRQSLKLNVAQSPNASDSSWAGMPYT
LYADGALLKQGVLDERGQISVDHQVVTRSYKLEMANGVSYQIPVAEAYSRPEQGELANRGFHHHTSQAASDINPPSSHTE
HRNTYADLLDGHIEQDESQ*

  Nucleotide sequence: 2700 bp    

>T6CP015383 NZ_FO834906:c3501690-3498991 [Klebsiella pneumoniae] [TssI]
ATGGATACCTCTTCAATAATTACCGGCACCACCCTTAACCGTTACCAGCTGGATATTCCTTCATGTGCCGCATCGCTGGA
TGTGGAAGAATTCAGTGGGGCAGAAAAACTGAGTGAACTTTATTATTACACTATTACGTTTACCAGCGCAGAGAAAAATA
TTGATGCCGCACAGCTCCTGAGCAAACCCGCCATGCTGACGATGGGCGGCGGCGCACTGCAGCAGTTGGCGGACTGCAAA
CGCGTCCATGGTGTGATTACCACCTTCCGGCGCGTCAATCGTTCTGAAGATCAGTCGACCTATCAGATAACCCTCCAGCC
GTTTCTCTCCCTGCTGGATAAACAGTTTCGCAGCCACCGTTTTTTCGTCAACAAATCGGTGCCGGAGGTGGTGGAGCAGG
TATTGCAGGAACATCACCTGCATGACTGGGAGTATGAGTTTAATCTCAAGCAACACTATCCGCGGCGCGAGCAAATTAAT
CAGTATCAGGAGAGCGACCTGGCATTTATCCAGCGCCTGCTGGCAGAGGTGGGGATATTTTATTTCTTCACCCTGCAGGA
AGAGGCGCAGAGCGAAGTGGTTCACTTCGCCGACGCGCAGCGGGCGCTGATGTTCGATAAGACACTTCCTGTAAACAGCC
CGTCCGGGATGAGCGACAGCGGTGCGGAATCGATATGGGGTCTGAGCATCACCCACAACGTCGTAGAGGCGAACGTCACT
ACCCGGGATTATAACCCCCGCGATGCGCAGAGCGTTCTCCAGTCGGCAACAGCGGATATGACCCGGGGAAATGGTGAAGG
CATCACTTACGGTGAGGTATACCACTATAAGCTTCGCCACCGGGAGCGTGGCGATAAAATCGAGCCGCAGACGGAGACCG
CCAACTTTTATGCCCGCCTCGACCATGAGCGTTTTCTGGCTCACCAGACGCTTATTACCGCGAGCAGTACTGCAGCCTGG
CTGGCGCCGGCCCAGGTGCTGACCGTTACCGACAGCCTGCCGTCGACCCTGCCTGCGCCCGTACAGGATCCGCTGTTAAT
CACCGGCACCGGTTTTACCGCCAGCCGCCGGGAGGCGCTGCGGGTGTCCCTGCTGGCGGTGCCCTACAGCGAAACATTGT
GCTGGCGTCCGCCGCTGCTGCCGCGCCCGAAGGTGACTGGCACCATGACGGCGCGGGTGACCAGCGCGAAAGCGAATGAT
ATCTACGCCTGGCAGGATGCGTCCGGCCTGTACCGGGTGAAATTTGACGCTGACAGAGATGAGAAAGGGCAGGGTCAGGA
AAGCATGCCGGTGCGTCTCGCCAAACCCTACGGCGGCGACGTGTACGGCTTTCACTTCCCGCTGATCCAGGGCACGGAGG
TGGCGATTGCTTTCCACGAAGGCGACCCTGACCGGCCGTATATTGCGCATGCGCTGCACGACTCGCGGCATGTCGATCCT
GTGACGGAGAAAAACAGCACCCGCAATGTGATTCGTACTCCGGCCAATAATAAGCTGCGAATGGAGGACAAGCGCGGCGA
GGAGCATATCAAGCTCAGCACCGATTACGGCGGCAAGACGCAGCTGAACCTGGGGCATAACGTGAATGCGCAAAGGGAGT
TGCGGGGCGAGGGGTTTGAGCTCCGGACGGATAAATGGGGGGCGATACGGGCGGGGAAAGGGATCTTTATCACCGCAGAT
AAACAGTCAACCGCCAGCGGCAAGATACTTGCAATGCAGGATACCCTGGACAGGCTTAAGCAGGCAGGTGATGAGATGGA
CTCGCTATCGCGTGATGCCCAGTCGGCTAAAGCCGACCCAGCCCAGGTTGAACAACAGTTAGCTTTTATGCGTGAGCAAA
TTGATCAGCTACGGGAGGCGGTTGCCGTGCTCAGCGCACCAAATGGTGTGGCTCTCGCCAGTGGCAAGCATCTGCAACTA
ACCGCACGTCGCAATCTGATGCTCAATGCCGGGGCAGATGCCGATATGGGCGTAATGAAACGGCTGTTTATTGGCGTGGG
GGAAGGGCTGAGCCTGTTTGTCCGCAAGCTGGGGATGAAATTAATCGCCAATCAGGGGCCCGTGGCGATTCAGGCGCAAA
ACGATCAGTTGCAGCTCCTGGCGCGCAAGGAGCTGGAGATTGTCAGTACTGATAGCGAAATTCACATTGTGGCAAAGAAA
AAAATCATCATTAACGCTGGAGGAAGCTATATCACCCTCGATCCCTATCGGATTGAGCTCGGTACTGGCGGTGATGTCGA
CGTCAAAGCCGCGGATTTTTCCTATAGCGGACCCGCCAGCATGAAGGCCGATCATCCGGATTATCCGCCACTTCAGTCCA
CCGTAAGGCAATCGCTGAAACTGAACGTGGCACAGTCGCCAAATGCGTCGGACAGCAGCTGGGCCGGAATGCCATATACC
CTGTATGCCGATGGCGCATTGTTGAAACAAGGGGTGCTGGATGAAAGAGGTCAGATATCAGTCGATCACCAGGTCGTGAC
CAGAAGTTACAAGCTGGAGATGGCTAATGGCGTCAGCTATCAGATACCCGTTGCCGAAGCGTACAGTCGCCCTGAGCAGG
GGGAACTCGCTAATCGCGGCTTTCACCACCATACCTCGCAGGCTGCATCTGATATTAACCCCCCCTCCTCACATACGGAG
CACCGTAATACTTACGCGGATTTGCTCGATGGCCATATTGAACAGGACGAAAGTCAATGA