Detailed information of component protein


Summary

Component ID T6CP015374
Component protein type TssA
T6SS ID (Type) T6SS01215 experimental (Type i2)
Strain Klebsiella pneumoniae strain Kp52.145
Replicon chromosome
Sequence Protein sequence (531 a.a.); Nucleotide sequence (1593 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) BN49_RS14080
Coordinate (Strand) 2584412..2586004 (+)
NCBI ID WP_004183804.1
RefSeq NZ_FO834906
Uniprot ID A0A7U7F3L3_KLEPN, W1EGQ2_KLEPN, W9BGC8_KLEPN
KEGG ID kpnk:BN49_2476
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
T6SS_VasJ PF16989.7 2e-72 228..487
ImpA_N PF06812.14 4.2e-21 33..128
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-530 MSILQNLVAASQLDESVLRQQARSRQAQWQSWLAPISDAQPTGDDPGYDDDFQRIRDEVNKISGVDTELICQLAEKLLTQTCKDLRVITFYVWARLQRDGETGLAEGVTLLAAMLERFGAMLHPQRERSCKSALEWLGSRRMSDSLSLYPEVDMTTMQVIIGALLLAEATFSGLAEASRPDLSGLYQILENRLVQSGGAHSLVPQTSREEHDLLPQHTDTAPVMHTVTSGRDLLDQAKVLAKYLRECPGGWLAGHHLMKSVRWDTLTELPPLDASGRTRLLPPKPESKAHLKRLYLQKSWSELLEHTDTLLAQGVNHLWLDVQWYAWQALLKLDADSVRADILCRDMKGLLARLPGLETLAFNDGTPFADEVTLNWLNERVLDEMAGWQDEPVMAATSADEVLSLEPEVLTRADDEGIESALNWLQAQPGYTTSRNRWLMRLLMARVSEQYGKNEMALHLLAELDSRAREMTLEQWKPELIFEVKARRLRLLRGKAGRSEAEKNRLLPEMESLLAGLIALDPARAAVLCA


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9778 - -


  Protein sequence: 531 a.a.    

>T6CP015374 NZ_FO834906:2584412-2586004 [Klebsiella pneumoniae] [TssA]
MSILQNLVAASQLDESVLRQQARSRQAQWQSWLAPISDAQPTGDDPGYDDDFQRIRDEVNKISGVDTELICQLAEKLLTQ
TCKDLRVITFYVWARLQRDGETGLAEGVTLLAAMLERFGAMLHPQRERSCKSALEWLGSRRMSDSLSLYPEVDMTTMQVI
IGALLLAEATFSGLAEASRPDLSGLYQILENRLVQSGGAHSLVPQTSREEHDLLPQHTDTAPVMHTVTSGRDLLDQAKVL
AKYLRECPGGWLAGHHLMKSVRWDTLTELPPLDASGRTRLLPPKPESKAHLKRLYLQKSWSELLEHTDTLLAQGVNHLWL
DVQWYAWQALLKLDADSVRADILCRDMKGLLARLPGLETLAFNDGTPFADEVTLNWLNERVLDEMAGWQDEPVMAATSAD
EVLSLEPEVLTRADDEGIESALNWLQAQPGYTTSRNRWLMRLLMARVSEQYGKNEMALHLLAELDSRAREMTLEQWKPEL
IFEVKARRLRLLRGKAGRSEAEKNRLLPEMESLLAGLIALDPARAAVLCA*

  Nucleotide sequence: 1593 bp    

>T6CP015374 NZ_FO834906:2584412-2586004 [Klebsiella pneumoniae] [TssA]
ATGAGCATTTTACAAAATTTGGTTGCCGCCAGTCAGTTGGATGAAAGCGTACTGCGCCAGCAGGCCCGGTCACGTCAGGC
GCAGTGGCAGTCCTGGCTTGCGCCAATCAGTGACGCCCAACCAACCGGGGACGATCCGGGCTATGACGATGATTTTCAGC
GTATCCGCGATGAGGTCAATAAGATCTCCGGCGTCGATACCGAACTGATTTGCCAGCTGGCAGAAAAACTGCTGACTCAG
ACCTGCAAGGATCTGCGCGTGATCACCTTTTACGTGTGGGCGCGTCTGCAGCGGGATGGTGAAACCGGTCTGGCGGAGGG
CGTTACGCTGCTGGCGGCAATGCTTGAGCGGTTTGGGGCTATGCTCCATCCCCAGCGTGAACGTAGCTGTAAATCAGCGC
TGGAATGGCTTGGCAGTCGCCGGATGTCGGACAGTCTGTCTCTTTATCCGGAAGTCGACATGACCACTATGCAGGTCATT
ATCGGGGCGTTATTGCTGGCGGAAGCCACTTTTTCCGGCTTGGCTGAAGCATCTCGCCCCGATCTTTCCGGGCTATATCA
GATACTGGAGAACCGCCTGGTGCAAAGCGGCGGAGCCCACAGTCTGGTGCCGCAGACCAGCCGCGAAGAACACGATCTGC
TACCCCAACATACGGACACCGCACCGGTAATGCATACCGTCACGTCAGGTCGTGATTTGCTCGATCAGGCTAAGGTGCTG
GCGAAATATCTGCGCGAGTGTCCCGGCGGATGGCTGGCAGGTCATCATCTGATGAAGAGTGTGCGTTGGGATACGTTAAC
GGAGTTACCGCCGCTGGATGCCTCCGGCCGGACACGGCTATTGCCTCCCAAGCCTGAGAGTAAAGCCCATCTTAAGCGGT
TGTATTTACAGAAAAGCTGGTCGGAACTGCTGGAGCATACGGACACGCTGTTGGCGCAAGGCGTCAACCATCTGTGGCTG
GATGTGCAGTGGTACGCCTGGCAGGCGCTGCTGAAACTGGATGCTGACAGTGTACGGGCCGATATCCTGTGCCGGGATAT
GAAAGGGCTATTGGCTCGTCTGCCGGGGCTGGAAACCCTGGCGTTTAACGATGGTACGCCATTCGCCGATGAAGTGACGC
TCAACTGGCTTAACGAACGTGTCCTGGATGAGATGGCCGGATGGCAAGATGAGCCGGTAATGGCGGCGACCAGCGCTGAT
GAGGTGCTGTCGCTGGAGCCAGAAGTGCTCACCCGCGCGGACGATGAAGGTATTGAGTCGGCGCTGAACTGGTTACAGGC
GCAGCCGGGCTATACCACCAGCCGCAATCGGTGGCTGATGCGCTTACTGATGGCGCGGGTCAGCGAGCAGTACGGAAAAA
ATGAAATGGCGCTGCATCTGCTGGCGGAACTCGACAGCCGCGCCCGGGAAATGACGCTCGAACAATGGAAGCCGGAGCTT
ATCTTTGAGGTCAAAGCCCGCCGACTCCGGCTGCTCAGAGGCAAGGCCGGGCGCAGTGAGGCAGAAAAAAATCGCTTGCT
GCCAGAAATGGAGTCATTGCTTGCCGGGCTCATCGCTCTGGATCCTGCTCGCGCCGCGGTGCTGTGCGCATAA