Detailed information of component protein


Summary

Component ID T6CP015372
Component protein type TssH
T6SS ID (Type) T6SS01215 experimental (Type i2)
Strain Klebsiella pneumoniae strain Kp52.145
Replicon chromosome
Sequence Protein sequence (885 a.a.); Nucleotide sequence (2655 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) BN49_RS14050
Coordinate (Strand) 2571115..2573769 (+)
NCBI ID WP_046043127.1
RefSeq NZ_FO834906
Uniprot ID W9B7B9_KLEPN
KEGG ID kpnk:BN49_2469
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
AAA_2 PF07724.16 9.2e-38 610..775
AAA_lid_9 PF17871.3 1.3e-30 378..468
ClpB_D2-small PF10431.11 1.9e-12 784..855
AAA PF00004.31 1.2e-09 238..350
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-884 MENPASLLRRLNPCCARAMEGAASLCQTRAHAEILPEHWLLKLLEQGEGDLTVLARRYEWDMDALWQDLLSWLDKQPRSVRHRPQLSDHTLRLMQEAWLIASLSGEAQIRSVHLLMALVEKQNLIQCDGLWPLLTLGQRQLERLRPLLDAQSDERPPAQQEAALAQPHGGDVEFVGRPAGSELNADGLNPALQNALDKFTLDVTAKARDGLIDPVFGRDTEIRQMVDILSRRRKNNPILVGEPGVGKTALVEGLALRIAEGNVPDALKPVSVRTLDLGLLQAGAGVKGEFEQRLKNIIEAVQQSPSPVLLFIDEAHTIIGAGNQGGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKSRYADHHGVHITDDAVRAAVTLSRRYLTGRQLPDKAVDLLDTASARLRMSLDTVPEPLTRMKAQLTALAMEKQALLEDIALGNSARGDRLAAIEQEEIRLILALDTLETQYGQELQLTEALLACRRDISRQAEINDLQTALIAVQQGNPLLGLDVDVRTVATVIADWTGVPLSSLMKDEQTELLSLEESLGKRVVGQEAALSAIARRLRAAKTGLTPENGPQGVFLLVGPSGTGKTEKALALADALFGGEKALITINLSEYQEPHTVSQLKGSPPGYVGYGQGGILTEAVRKRPYSVVLLDEVEKAHRDVMNLFYQVFDRGVMRDGEGREIDFRNTVILMTANLGSDLLMQLLDEQPEASESDLHELLRPVLRGHFQPALLARFQTVIYRPLPAGALRAIVGMKLGQVSQRLACHYGITTTLSESLFDALTEACLLPDTGARNVDSLLNQQILPALSQQLLSHMAAGQKPRQVTLGYHEEEGVVMAFDEGTISDE


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8846 - -


  Protein sequence: 885 a.a.    

>T6CP015372 NZ_FO834906:2571115-2573769 [Klebsiella pneumoniae] [TssH]
MENPASLLRRLNPCCARAMEGAASLCQTRAHAEILPEHWLLKLLEQGEGDLTVLARRYEWDMDALWQDLLSWLDKQPRSV
RHRPQLSDHTLRLMQEAWLIASLSGEAQIRSVHLLMALVEKQNLIQCDGLWPLLTLGQRQLERLRPLLDAQSDERPPAQQ
EAALAQPHGGDVEFVGRPAGSELNADGLNPALQNALDKFTLDVTAKARDGLIDPVFGRDTEIRQMVDILSRRRKNNPILV
GEPGVGKTALVEGLALRIAEGNVPDALKPVSVRTLDLGLLQAGAGVKGEFEQRLKNIIEAVQQSPSPVLLFIDEAHTIIG
AGNQGGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKSRYADHHGVHI
TDDAVRAAVTLSRRYLTGRQLPDKAVDLLDTASARLRMSLDTVPEPLTRMKAQLTALAMEKQALLEDIALGNSARGDRLA
AIEQEEIRLILALDTLETQYGQELQLTEALLACRRDISRQAEINDLQTALIAVQQGNPLLGLDVDVRTVATVIADWTGVP
LSSLMKDEQTELLSLEESLGKRVVGQEAALSAIARRLRAAKTGLTPENGPQGVFLLVGPSGTGKTEKALALADALFGGEK
ALITINLSEYQEPHTVSQLKGSPPGYVGYGQGGILTEAVRKRPYSVVLLDEVEKAHRDVMNLFYQVFDRGVMRDGEGREI
DFRNTVILMTANLGSDLLMQLLDEQPEASESDLHELLRPVLRGHFQPALLARFQTVIYRPLPAGALRAIVGMKLGQVSQR
LACHYGITTTLSESLFDALTEACLLPDTGARNVDSLLNQQILPALSQQLLSHMAAGQKPRQVTLGYHEEEGVVMAFDEGT
ISDE*

  Nucleotide sequence: 2655 bp    

>T6CP015372 NZ_FO834906:2571115-2573769 [Klebsiella pneumoniae] [TssH]
ATGGAAAATCCAGCCAGCCTGTTACGCCGTCTTAATCCCTGCTGTGCCCGCGCAATGGAGGGGGCGGCCTCCCTGTGCCA
GACCCGGGCGCATGCCGAGATCCTGCCCGAGCACTGGCTGCTCAAGCTGCTGGAACAGGGGGAAGGTGATCTGACGGTGC
TGGCGCGGCGCTATGAATGGGATATGGATGCGCTGTGGCAGGATCTGCTGAGCTGGCTGGATAAACAGCCGCGCTCGGTA
CGTCATCGTCCCCAGCTCTCTGACCATACCCTGAGGCTGATGCAGGAGGCCTGGCTGATTGCCTCTCTCAGCGGCGAAGC
GCAGATCCGCAGTGTTCACCTGCTGATGGCGCTGGTTGAAAAACAGAATCTGATCCAGTGCGATGGCCTGTGGCCGCTGT
TAACGCTGGGCCAGCGTCAGCTGGAACGCCTGCGCCCCTTGCTGGATGCCCAGTCCGACGAACGTCCGCCAGCGCAGCAG
GAAGCGGCGCTGGCGCAGCCCCATGGCGGGGACGTGGAATTTGTGGGGCGTCCCGCGGGCAGCGAACTGAATGCGGATGG
GCTCAACCCGGCGCTGCAGAACGCGCTGGACAAATTCACTCTCGACGTCACCGCCAAAGCCAGAGACGGCCTGATTGACC
CGGTGTTCGGACGTGACACGGAAATCCGCCAGATGGTGGATATTCTCTCCCGTCGACGTAAAAACAACCCGATCCTCGTC
GGTGAGCCGGGCGTGGGCAAGACCGCTCTGGTGGAAGGCCTGGCGCTGCGCATTGCCGAAGGCAACGTCCCCGACGCGCT
GAAGCCGGTGTCGGTGCGCACCCTCGACCTCGGTCTGCTGCAGGCCGGCGCCGGGGTCAAAGGCGAGTTCGAGCAGCGGC
TGAAAAATATCATTGAGGCGGTACAGCAGTCGCCTTCGCCGGTGCTGCTGTTTATCGACGAGGCGCACACGATCATCGGC
GCGGGTAATCAGGGGGGCGGCGCGGATGCCGCCAACCTGCTGAAGCCGGCGCTGGCCCGGGGCGAACTGCGGACCATCGC
CGCCACCACCTGGTCTGAATACAAGCAGTACTTCGAGCGCGACGCCGCGCTGGAGCGCCGCTTTCAGATGGTCAAGGTGG
ATGAGCCGGACGACGACACCGCCTGCCTGATGCTGCGCGGCCTGAAGTCCCGCTATGCCGACCACCACGGCGTGCATATC
ACGGATGATGCGGTGCGCGCCGCCGTGACGCTGTCACGACGCTATCTCACCGGTCGCCAGCTGCCGGACAAGGCAGTGGA
TTTACTCGACACCGCTTCCGCCCGCCTGCGTATGAGTTTGGATACCGTGCCTGAGCCGCTGACCCGCATGAAGGCGCAGC
TCACCGCGCTGGCAATGGAGAAGCAGGCGCTGCTGGAAGATATTGCGCTGGGCAACAGCGCCCGCGGCGATCGGCTGGCG
GCCATTGAGCAGGAGGAGATCCGCCTTATTCTGGCGCTGGATACCCTTGAAACTCAGTATGGTCAGGAGCTGCAGCTGAC
GGAAGCGCTGCTCGCCTGTCGCCGCGATATCTCCCGCCAGGCGGAAATTAACGACCTGCAAACCGCGCTTATCGCCGTCC
AGCAGGGCAATCCGCTGCTCGGGCTGGACGTCGACGTCCGCACCGTGGCGACGGTGATTGCCGACTGGACCGGCGTGCCG
CTCTCCTCGCTAATGAAAGATGAGCAGACGGAGCTGCTGAGTCTGGAAGAGAGTCTCGGCAAACGGGTGGTTGGCCAGGA
GGCGGCCCTGAGCGCTATTGCCCGGCGCCTGCGCGCCGCGAAAACCGGCCTGACGCCGGAGAACGGTCCGCAAGGGGTGT
TCCTGCTGGTCGGGCCGAGCGGCACCGGCAAAACGGAAAAGGCGCTCGCCCTGGCCGATGCGCTGTTCGGCGGCGAGAAA
GCGCTGATCACCATCAATCTCTCCGAGTACCAGGAGCCGCACACCGTCAGCCAGCTGAAGGGTTCTCCGCCCGGCTACGT
CGGCTACGGCCAGGGCGGGATCCTGACCGAGGCGGTGCGCAAACGCCCCTACAGCGTGGTGCTGCTCGATGAGGTGGAAA
AGGCCCATCGCGATGTGATGAACCTGTTCTACCAGGTCTTCGACCGGGGGGTAATGCGCGACGGCGAGGGGCGTGAAATC
GACTTTCGCAACACAGTGATCCTGATGACCGCCAACCTCGGAAGCGACCTCCTGATGCAGTTGCTGGATGAACAGCCGGA
GGCCAGTGAATCAGACCTGCACGAGCTGCTGCGCCCGGTGCTGCGCGGCCACTTCCAGCCGGCGCTGCTGGCCCGCTTCC
AGACGGTGATTTACCGTCCGCTGCCGGCGGGAGCGCTGCGCGCCATTGTCGGCATGAAGCTCGGGCAGGTAAGTCAGCGT
CTGGCTTGCCATTACGGAATCACCACCACCCTCAGCGAGAGCCTGTTCGACGCGCTGACCGAGGCCTGCCTGCTGCCGGA
TACCGGCGCCCGCAACGTCGACAGTCTGCTGAATCAGCAGATCCTGCCGGCACTGAGTCAGCAGCTATTGAGCCATATGG
CGGCGGGGCAGAAACCGCGCCAGGTGACGCTGGGGTATCACGAAGAGGAAGGCGTCGTGATGGCGTTTGACGAGGGGACA
ATATCCGATGAGTAG