Detailed information of component protein
Summary
| Component ID | T6CP015371 |
| Component protein type | TssL |
| T6SS ID (Type) | T6SS01215  (Type i2) |
| Strain | Klebsiella pneumoniae strain Kp52.145 |
| Replicon | chromosome |
| Sequence | Protein sequence (230 a.a.); Nucleotide sequence (690 bp) |
| Reference |
Experimental investigation has been performed on this T6SSExternal database links
| Locus tag (Gene) | BN49_RS14035 |
| Coordinate (Strand) | 2567962..2568651 (+) |
| NCBI ID | WP_004176431.1 |
| RefSeq | NZ_FO834906 |
| Uniprot ID | A0A7U7IGM2_KLEPN, V0B0K3_KLEPN, A0A7H4SFI2_KLEVA, A0A652Q1E0_9ENTR, A6T836_KLEP7, A0A3S4MD95_KLEAE, W9BP37_KLEPN, A0A377ZU02_KLEPN |
| KEGG ID | kpnk:BN49_2465, kpk:A593_21460, kpn:KPN_01325, kpv:KPNIH29_11390, kpy:KPNIH31_11040, kpt:VK055_1103 |
| PDB ID | - |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| DotU | PF09850.11 | 3.3e-30 | 14..215 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-229 | VNEPKRGNAASIDIDALLQNTWLQVISLRHGPQFRDEEGYTLWQRCIADVERVQHELKASGLDDASCQHILTAQCALLDEAVKGRGVEDEACLQWYDIPLQGHFLGTMDAGDTLCERMRDVLREPAPNLAVVTCFQRVMLLGFIGSFRSLHDPERLKLVNALGERVPPFQCPATAPVLVESRAGLGISGWLAPWPVRIGLSVVVVLALWWGLNHWLDHLLLTLLPGEVK |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9974 | - | - |
Protein sequence: 230 a.a.
>T6CP015371 NZ_FO834906:2567962-2568651 [Klebsiella pneumoniae] [TssL]
VNEPKRGNAASIDIDALLQNTWLQVISLRHGPQFRDEEGYTLWQRCIADVERVQHELKASGLDDASCQHILTAQCALLDE
AVKGRGVEDEACLQWYDIPLQGHFLGTMDAGDTLCERMRDVLREPAPNLAVVTCFQRVMLLGFIGSFRSLHDPERLKLVN
ALGERVPPFQCPATAPVLVESRAGLGISGWLAPWPVRIGLSVVVVLALWWGLNHWLDHLLLTLLPGEVK*
VNEPKRGNAASIDIDALLQNTWLQVISLRHGPQFRDEEGYTLWQRCIADVERVQHELKASGLDDASCQHILTAQCALLDE
AVKGRGVEDEACLQWYDIPLQGHFLGTMDAGDTLCERMRDVLREPAPNLAVVTCFQRVMLLGFIGSFRSLHDPERLKLVN
ALGERVPPFQCPATAPVLVESRAGLGISGWLAPWPVRIGLSVVVVLALWWGLNHWLDHLLLTLLPGEVK*
Nucleotide sequence: 690 bp
>T6CP015371 NZ_FO834906:2567962-2568651 [Klebsiella pneumoniae] [TssL]
GTGAATGAGCCTAAACGCGGCAACGCCGCGTCCATTGATATTGATGCGCTGCTGCAGAACACCTGGCTGCAGGTTATCAG
CCTGCGCCACGGCCCGCAGTTCCGCGATGAGGAAGGGTACACGCTATGGCAGCGCTGTATTGCTGATGTCGAGCGCGTGC
AACATGAGCTGAAGGCGAGCGGGCTTGATGACGCCAGCTGTCAGCATATTCTCACCGCCCAGTGCGCGCTGCTCGATGAA
GCCGTGAAAGGGCGCGGCGTGGAGGATGAGGCCTGCCTGCAGTGGTATGACATTCCGCTGCAGGGGCACTTCCTCGGCAC
CATGGACGCCGGCGACACCCTGTGCGAGCGGATGCGTGATGTATTGCGTGAACCGGCGCCCAACCTGGCCGTGGTCACCT
GTTTTCAGCGGGTGATGCTGCTGGGTTTTATTGGCAGCTTTCGCTCCCTCCACGACCCCGAGCGCCTGAAGCTGGTCAAC
GCGCTCGGTGAGCGTGTTCCTCCTTTTCAGTGCCCGGCTACCGCTCCCGTACTGGTAGAGAGTCGCGCCGGCCTGGGGAT
AAGCGGCTGGCTGGCCCCATGGCCGGTACGTATTGGCCTGAGCGTGGTAGTGGTACTCGCCCTGTGGTGGGGGCTCAACC
ACTGGCTCGATCACCTGCTGCTGACCTTGTTACCGGGGGAGGTGAAATGA
GTGAATGAGCCTAAACGCGGCAACGCCGCGTCCATTGATATTGATGCGCTGCTGCAGAACACCTGGCTGCAGGTTATCAG
CCTGCGCCACGGCCCGCAGTTCCGCGATGAGGAAGGGTACACGCTATGGCAGCGCTGTATTGCTGATGTCGAGCGCGTGC
AACATGAGCTGAAGGCGAGCGGGCTTGATGACGCCAGCTGTCAGCATATTCTCACCGCCCAGTGCGCGCTGCTCGATGAA
GCCGTGAAAGGGCGCGGCGTGGAGGATGAGGCCTGCCTGCAGTGGTATGACATTCCGCTGCAGGGGCACTTCCTCGGCAC
CATGGACGCCGGCGACACCCTGTGCGAGCGGATGCGTGATGTATTGCGTGAACCGGCGCCCAACCTGGCCGTGGTCACCT
GTTTTCAGCGGGTGATGCTGCTGGGTTTTATTGGCAGCTTTCGCTCCCTCCACGACCCCGAGCGCCTGAAGCTGGTCAAC
GCGCTCGGTGAGCGTGTTCCTCCTTTTCAGTGCCCGGCTACCGCTCCCGTACTGGTAGAGAGTCGCGCCGGCCTGGGGAT
AAGCGGCTGGCTGGCCCCATGGCCGGTACGTATTGGCCTGAGCGTGGTAGTGGTACTCGCCCTGTGGTGGGGGCTCAACC
ACTGGCTCGATCACCTGCTGCTGACCTTGTTACCGGGGGAGGTGAAATGA