Detailed information of component protein


Summary

Component ID T6CP015370
Component protein type TssK
T6SS ID (Type) T6SS01215 experimental (Type i2)
Strain Klebsiella pneumoniae strain Kp52.145
Replicon chromosome
Sequence Protein sequence (448 a.a.); Nucleotide sequence (1344 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) BN49_RS14030
Coordinate (Strand) 2566622..2567965 (+)
NCBI ID WP_171819472.1
RefSeq NZ_FO834906
Uniprot ID UPI00042ED61C
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
T6SS_VasE PF05936.14 8.5e-135 19..444
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-447 MMKTERPLWGRGIMVSPQHFQQQAAYAAWTAEVIARMGLNHPWGVVEATFEPEMLKLGRLQAHRLQVRFQDGTMIDTDNADALPSALSLDGASGEAVIVLALPLMQANGGNCLKPEEVAERPVRFRQRWRDVRNQFGDDTRQIAVIQPELILRFAHQDNSDYLTCPLVRLQRDSQGAWLIDETFLPPLLQIQGSRWLATQLEQLLVQLRARLTRLMAMRRESNERMADFAVADVSLFWLLNALNSAEPVLGYFLRYRQSPPERLYPELARLAGSLLTFSLTHQANAVPIYQHDQLNAVFPPLFDLLNDLLEASLPSRVVAIALEHDVRLHFWQARLHDARLREGADYYLSVRSSVPVAQLQEQFLHQCKVGSPDHVKAIVNSSRTGVPLTPLRHVPAAIPLRLENQYFSLDVSHPLATEMLQSGTCMFYVPGMLGEPELELFAVLRT


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9605 - -


  Protein sequence: 448 a.a.    

>T6CP015370 NZ_FO834906:2566622-2567965 [Klebsiella pneumoniae] [TssK]
MMKTERPLWGRGIMVSPQHFQQQAAYAAWTAEVIARMGLNHPWGVVEATFEPEMLKLGRLQAHRLQVRFQDGTMIDTDNA
DALPSALSLDGASGEAVIVLALPLMQANGGNCLKPEEVAERPVRFRQRWRDVRNQFGDDTRQIAVIQPELILRFAHQDNS
DYLTCPLVRLQRDSQGAWLIDETFLPPLLQIQGSRWLATQLEQLLVQLRARLTRLMAMRRESNERMADFAVADVSLFWLL
NALNSAEPVLGYFLRYRQSPPERLYPELARLAGSLLTFSLTHQANAVPIYQHDQLNAVFPPLFDLLNDLLEASLPSRVVA
IALEHDVRLHFWQARLHDARLREGADYYLSVRSSVPVAQLQEQFLHQCKVGSPDHVKAIVNSSRTGVPLTPLRHVPAAIP
LRLENQYFSLDVSHPLATEMLQSGTCMFYVPGMLGEPELELFAVLRT*

  Nucleotide sequence: 1344 bp    

>T6CP015370 NZ_FO834906:2566622-2567965 [Klebsiella pneumoniae] [TssK]
ATGATGAAAACGGAACGTCCGTTGTGGGGCCGGGGCATTATGGTGTCGCCTCAGCATTTTCAACAGCAGGCTGCGTATGC
AGCCTGGACTGCGGAAGTGATTGCCCGGATGGGTCTTAACCACCCCTGGGGAGTGGTTGAGGCGACCTTCGAACCAGAGA
TGCTCAAACTGGGCCGCCTGCAGGCTCACAGGCTGCAGGTCCGGTTCCAGGATGGCACGATGATTGATACGGACAATGCC
GATGCGCTGCCGTCCGCGCTGTCGCTGGACGGCGCGTCCGGCGAGGCGGTGATCGTGCTGGCGCTGCCCCTGATGCAGGC
GAATGGCGGCAACTGTCTGAAGCCGGAGGAGGTGGCCGAAAGGCCGGTGCGCTTCCGGCAGCGCTGGCGCGATGTCCGTA
ACCAGTTTGGGGATGATACCCGGCAGATTGCCGTCATACAGCCGGAGCTGATCCTCCGCTTCGCCCACCAGGACAACAGC
GATTACCTGACCTGTCCGCTTGTTCGCCTGCAGCGGGACTCGCAGGGGGCCTGGCTTATCGACGAGACGTTTCTCCCGCC
GCTGCTGCAGATCCAGGGCAGCCGCTGGCTGGCGACGCAGCTTGAACAGCTGCTCGTCCAGCTCCGGGCTCGTCTGACGC
GCCTGATGGCCATGCGTCGCGAAAGCAATGAACGGATGGCTGATTTTGCCGTAGCCGATGTCTCTCTGTTCTGGTTGCTG
AATGCGCTGAACAGCGCCGAACCGGTGCTGGGGTACTTTCTGCGTTACCGGCAAAGCCCGCCGGAACGCCTCTACCCGGA
GCTGGCGCGCCTGGCTGGTAGCCTGCTGACCTTTTCGCTCACCCATCAGGCGAATGCCGTCCCGATCTATCAGCATGACC
AGCTGAACGCGGTTTTTCCGCCGCTGTTTGATTTACTGAACGACCTGCTGGAGGCGAGCCTGCCATCGCGGGTGGTGGCG
ATTGCGCTGGAGCATGATGTCCGGCTGCACTTCTGGCAGGCGCGTCTGCACGATGCCCGGCTGCGGGAAGGGGCTGATTA
CTACCTGTCGGTTCGTTCGTCGGTACCGGTCGCCCAACTGCAGGAGCAGTTTCTGCACCAGTGCAAAGTGGGCAGTCCGG
ATCATGTCAAAGCCATCGTCAACTCCTCGCGGACAGGGGTGCCCCTCACGCCATTGCGTCATGTGCCGGCGGCGATCCCG
CTGCGTCTGGAAAATCAGTATTTCAGCCTCGATGTGTCCCACCCTCTGGCAACGGAAATGCTGCAGAGCGGCACCTGTAT
GTTTTACGTCCCGGGGATGCTCGGTGAGCCTGAACTTGAACTTTTTGCGGTACTACGAACGTGA