Detailed information of component protein


Summary

Component ID T6CP015363
Component protein type TssM
T6SS ID (Type) T6SS01214 experimental (Type Unknown)
Strain Klebsiella pneumoniae strain Kp52.145
Replicon chromosome
Sequence Protein sequence (1122 a.a.); Nucleotide sequence (3366 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) BN49_RS06000
Coordinate (Strand) 957862..961227 (-)
NCBI ID WP_046042502.1
RefSeq NZ_FO834906
Uniprot ID W9BN83_KLEPN
KEGG ID kpnk:BN49_0939
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 1.7e-59 403..718
IcmF_C PF06744.14 9.2e-24 979..1082
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-6 MKSANN
Transmembrane helix 7-29 KLTIIADVLLLLLFAAVLGFIIW
Outside 30-43 RFGDLFGLTGDKNK
Transmembrane helix 44-66 FYIWLAGIMSFIFLRASWYFSRL
Inside 67-348 YRVRRERRQSEEQGEYPEKEIRYEPGQRTSLYSELFFHLRDRYGLFWQRQVRLLLVTGEPEQVEAIAPGLTEQRWQEGDHTVLIYGGKASAEPDTTLLASLKKLRRFRPLDGIIWPLTEKQSTQTAQLDKGWRELGNGGKLLGFQAPLYLWQVCDDGGYQAGRTLQSVGCLLPERSTPEQLATQLEAQTPQLTEQGMSQLLTNNRHDFLLRLAHTLTERGIAHWQTVLKPLLAGGAFPSLHLRGLMFSPPLAAVPEAAPHAWLSSLVWAGVTGDNAKGRTVG
Transmembrane helix 349-371 FPWLRTALMACFCVLAIWWTGMM
Outside 372-1121 TSFFANRALIQETGTHTARAINTRLPLAEQLVALHTLQGELERLQYRIRHGTPWYQRFGLERNAQLLNTAFPGYAQAANRLVRDVAVAHLQQQLNAFVALSPNSPQRTATGELRYKQLKALLMTSRPEKADAAFFSTTLKADNLRYADVTEGTRQSVLPSLLTFWMANLPEHPQWKIAPQPELVGAVRKILLRQIGVRNAENTLYQNVLKQVCRNYADMTLADMTGDTQAGSLFGTEQTVPGMFTRQAWEGQVKEAIEQVATARREEIDWVLSDRQQDASADISPEALRTRLMERYFTDFAGSWLTFLNSIRWKKEDSLSGVLDQLTLMADARQSPLIALTDTVAWQAAAGRESRSLSDSLTQSAKELFSGKEKTPQNTRAAREEEAPTGPMDKTFAPLLRLTGDKAGGTGDSQLSLQTYLTRVTRVRLKLQQVTNAPDPQEMTQQLAQTVLQGKTVDLTDTRDYGRLIAASLGEEWSGFGQSLFVRPVEQAWRQVLTPAADSLNRQWQRAIVSHWNQDFAGRYPFKNTPNDASLPLLAKYLRDDGRISQFIATNLAGVLEREGRYWVADTMNTQGLTVNPAFLRALNRLRDVADTAFASGDAGVHFELMAKPARDVMKTHLVIDGQQLEYFNQKERWQRFSWPDEQWQPGASLSWTSTQNMERILADFRGSWSFIRLLEQAQVTQLDSSSFMLQWQAPDGLPLHYLMRVEQGKGPLALLALKNFRLPGQVFLTGKAISDAEEYRDNADE


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9779 - -


  Protein sequence: 1122 a.a.    

>T6CP015363 NZ_FO834906:c961227-957862 [Klebsiella pneumoniae] [TssM]
MKSANNKLTIIADVLLLLLFAAVLGFIIWRFGDLFGLTGDKNKFYIWLAGIMSFIFLRASWYFSRLYRVRRERRQSEEQG
EYPEKEIRYEPGQRTSLYSELFFHLRDRYGLFWQRQVRLLLVTGEPEQVEAIAPGLTEQRWQEGDHTVLIYGGKASAEPD
TTLLASLKKLRRFRPLDGIIWPLTEKQSTQTAQLDKGWRELGNGGKLLGFQAPLYLWQVCDDGGYQAGRTLQSVGCLLPE
RSTPEQLATQLEAQTPQLTEQGMSQLLTNNRHDFLLRLAHTLTERGIAHWQTVLKPLLAGGAFPSLHLRGLMFSPPLAAV
PEAAPHAWLSSLVWAGVTGDNAKGRTVGFPWLRTALMACFCVLAIWWTGMMTSFFANRALIQETGTHTARAINTRLPLAE
QLVALHTLQGELERLQYRIRHGTPWYQRFGLERNAQLLNTAFPGYAQAANRLVRDVAVAHLQQQLNAFVALSPNSPQRTA
TGELRYKQLKALLMTSRPEKADAAFFSTTLKADNLRYADVTEGTRQSVLPSLLTFWMANLPEHPQWKIAPQPELVGAVRK
ILLRQIGVRNAENTLYQNVLKQVCRNYADMTLADMTGDTQAGSLFGTEQTVPGMFTRQAWEGQVKEAIEQVATARREEID
WVLSDRQQDASADISPEALRTRLMERYFTDFAGSWLTFLNSIRWKKEDSLSGVLDQLTLMADARQSPLIALTDTVAWQAA
AGRESRSLSDSLTQSAKELFSGKEKTPQNTRAAREEEAPTGPMDKTFAPLLRLTGDKAGGTGDSQLSLQTYLTRVTRVRL
KLQQVTNAPDPQEMTQQLAQTVLQGKTVDLTDTRDYGRLIAASLGEEWSGFGQSLFVRPVEQAWRQVLTPAADSLNRQWQ
RAIVSHWNQDFAGRYPFKNTPNDASLPLLAKYLRDDGRISQFIATNLAGVLEREGRYWVADTMNTQGLTVNPAFLRALNR
LRDVADTAFASGDAGVHFELMAKPARDVMKTHLVIDGQQLEYFNQKERWQRFSWPDEQWQPGASLSWTSTQNMERILADF
RGSWSFIRLLEQAQVTQLDSSSFMLQWQAPDGLPLHYLMRVEQGKGPLALLALKNFRLPGQVFLTGKAISDAEEYRDNAD
E*

  Nucleotide sequence: 3366 bp    

>T6CP015363 NZ_FO834906:c961227-957862 [Klebsiella pneumoniae] [TssM]
ATGAAATCTGCAAACAATAAGTTAACGATTATTGCAGACGTATTGCTGCTCCTGCTTTTTGCGGCTGTATTGGGTTTTAT
TATCTGGCGTTTTGGTGATCTTTTTGGATTAACCGGGGATAAAAATAAGTTTTATATATGGCTGGCTGGCATAATGTCGT
TTATTTTTCTGCGGGCATCCTGGTATTTTTCCCGTTTATACAGGGTTCGCAGGGAACGGCGGCAGTCTGAGGAACAGGGG
GAATACCCGGAAAAAGAAATTCGTTATGAACCTGGGCAAAGAACATCTTTGTATTCTGAACTATTTTTTCATCTTCGCGA
CCGTTACGGTCTGTTCTGGCAGCGTCAGGTCCGTCTGCTGCTGGTGACGGGCGAGCCTGAGCAGGTGGAAGCCATCGCGC
CGGGGCTGACAGAGCAGCGCTGGCAGGAAGGCGACCATACGGTGTTGATATATGGCGGCAAGGCGTCGGCAGAGCCGGAT
ACCACCCTGCTGGCCTCCCTGAAAAAACTGCGCCGCTTCCGCCCGCTGGACGGTATTATCTGGCCGCTGACGGAGAAACA
GAGTACCCAGACGGCGCAACTGGATAAGGGCTGGCGCGAACTGGGTAATGGTGGAAAATTGCTTGGCTTTCAGGCTCCGC
TGTATCTGTGGCAGGTCTGTGATGACGGAGGTTATCAGGCCGGGCGCACACTACAAAGCGTCGGCTGCCTGCTGCCGGAG
CGAAGCACACCGGAACAACTGGCTACACAACTGGAAGCACAGACCCCGCAACTGACGGAACAGGGAATGTCGCAGTTGCT
GACCAATAACCGGCACGATTTTCTGTTGCGTCTTGCCCACACACTTACAGAGCGCGGCATCGCTCACTGGCAAACCGTCC
TGAAGCCCTTGCTGGCAGGCGGCGCATTCCCTTCTCTGCACCTGCGCGGCCTGATGTTCAGCCCTCCACTGGCCGCCGTG
CCGGAAGCGGCTCCCCACGCGTGGCTGTCATCGCTGGTGTGGGCGGGCGTTACTGGCGACAATGCAAAAGGCCGCACCGT
GGGCTTTCCGTGGCTGCGCACCGCGCTGATGGCCTGCTTCTGCGTGCTGGCGATATGGTGGACCGGAATGATGACCTCGT
TCTTTGCCAACCGCGCCCTGATTCAGGAAACCGGGACGCACACAGCGCGGGCCATCAATACCCGACTGCCGCTGGCAGAG
CAACTGGTTGCGCTGCACACCTTGCAGGGCGAGCTCGAGCGTCTGCAGTATCGTATCCGCCACGGTACGCCGTGGTATCA
GCGTTTCGGTCTGGAGCGTAATGCTCAGTTGCTGAACACGGCGTTCCCCGGCTATGCGCAGGCGGCAAACCGACTGGTAC
GCGATGTAGCGGTCGCCCACCTGCAGCAGCAACTGAACGCCTTTGTCGCCCTGTCTCCGAACAGTCCGCAACGCACCGCA
ACGGGAGAACTGCGTTATAAGCAACTGAAGGCGCTGCTGATGACGTCCCGTCCCGAAAAAGCCGACGCCGCCTTTTTCAG
TACCACGCTGAAGGCAGATAACCTGCGCTATGCAGATGTAACGGAAGGTACCCGGCAAAGCGTGCTGCCGTCGCTGCTGA
CCTTCTGGATGGCGAATCTGCCGGAGCATCCACAGTGGAAAATCGCCCCGCAGCCGGAACTGGTCGGCGCGGTACGCAAA
ATTCTGCTGCGCCAGATTGGGGTGCGCAATGCGGAAAATACCCTCTATCAGAACGTCCTGAAACAGGTCTGCCGCAACTA
CGCCGATATGACGCTGGCGGATATGACCGGCGACACGCAGGCCGGCTCGTTGTTTGGTACTGAGCAAACGGTGCCGGGAA
TGTTCACCCGCCAGGCATGGGAAGGTCAGGTTAAGGAGGCCATAGAGCAGGTGGCGACGGCCCGACGTGAGGAAATCGAC
TGGGTACTCAGCGACCGTCAACAGGACGCTTCCGCCGATATTTCGCCGGAAGCCCTGCGTACCCGCCTGATGGAACGTTA
CTTCACCGACTTCGCCGGAAGCTGGCTGACATTCCTCAATAGCATTCGCTGGAAGAAAGAGGACTCGCTGTCCGGCGTGC
TGGACCAACTGACGCTGATGGCCGATGCCCGCCAGTCGCCGCTGATTGCGCTCACGGATACGGTGGCATGGCAGGCGGCG
GCAGGAAGGGAAAGCCGTAGTCTGTCAGACTCGCTGACACAATCAGCAAAAGAGTTGTTTAGCGGTAAAGAAAAAACACC
GCAGAACACCCGTGCCGCCCGTGAAGAAGAAGCACCAACGGGACCGATGGACAAAACCTTTGCCCCGCTGCTGCGGCTGA
CCGGTGATAAAGCCGGAGGCACTGGCGACAGCCAGCTCAGTCTGCAAACTTACCTCACCCGCGTGACCCGCGTGCGCCTC
AAGCTGCAACAGGTCACCAACGCCCCGGACCCGCAGGAGATGACGCAGCAGCTGGCGCAGACGGTATTGCAGGGCAAAAC
CGTCGACCTCACCGATACCCGAGATTATGGCCGTCTGATAGCCGCCAGTCTGGGCGAGGAATGGAGCGGCTTCGGCCAGT
CGCTGTTTGTTCGTCCGGTGGAGCAGGCGTGGCGGCAGGTGCTGACGCCCGCAGCGGACAGTCTGAACCGGCAGTGGCAG
CGGGCCATTGTCAGCCACTGGAATCAGGATTTCGCCGGGCGTTATCCGTTTAAGAACACTCCGAACGACGCCTCTCTCCC
CCTGCTGGCTAAATATCTGCGCGATGACGGACGTATAAGTCAGTTTATCGCTACCAACCTTGCAGGCGTTCTGGAACGCG
AAGGTCGTTATTGGGTGGCTGACACCATGAACACGCAGGGACTGACGGTCAACCCGGCGTTTTTACGCGCCCTGAATCGC
CTGCGCGATGTGGCCGACACAGCCTTTGCCAGCGGCGATGCCGGGGTACATTTTGAACTGATGGCAAAACCGGCACGTGA
CGTGATGAAAACGCATCTGGTGATTGACGGCCAGCAACTGGAATATTTCAACCAGAAAGAACGCTGGCAGCGTTTCAGCT
GGCCGGATGAGCAGTGGCAGCCTGGCGCATCGCTGAGCTGGACCAGTACGCAGAATATGGAACGTATTCTGGCCGACTTC
CGGGGAAGCTGGAGCTTTATTCGTCTGCTGGAACAGGCGCAGGTCACACAGCTGGACAGCAGCAGCTTTATGCTGCAGTG
GCAAGCGCCGGACGGTCTGCCGCTGCATTACCTGATGCGCGTCGAACAGGGTAAAGGGCCGTTGGCGCTGCTGGCGTTGA
AAAACTTCCGCCTGCCGGGACAGGTGTTTCTGACCGGGAAAGCCATAAGTGATGCAGAAGAATACAGGGACAACGCAGAT
GAGTGA