Detailed information of component protein


Summary

Component ID T6CP015188
Component protein type TssM
T6SS ID (Type) T6SS01196 experimental (Type i4b)
Strain Burkholderia cenocepacia H111
Replicon chromosome
Sequence Protein sequence (1309 a.a.); Nucleotide sequence (3927 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) I35_RS01770
Coordinate (Strand) 363912..367838 (-)
NCBI ID WP_043204521.1
RefSeq NZ_HG938370
Uniprot ID UPI0005BA7D0B
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 1.6e-95 498..871
IcmF-related_N PF14331.8 8.9e-83 194..447
IcmF_C PF06744.14 7.1e-22 1141..1244
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-12 MQRILNVLTHPR
Transmembrane helix 13-30 TLSIVGIVALAAILFIVA
Outside 31-34 DMLQ
Transmembrane helix 35-57 LPLLWAATAFAAILALWLVVALW
Inside 58-443 RRWRVKRANQQLGQVLEEQAETGKIAAPAAAALAPDAKTADLDVLRTRLSDAVKTIKTSKIGQVSGGSALYELPWYIVIGNPAAGKSSAVLNSGLQFPFADKNSAVIHGIGGTRNCDWFFTTEGILLDTAGRYSVHEEDRSEWLGFLGLLKRYRPKAPINGIIVTASIAELTGNRPEFAINLAKNLRQRVQELTEKLEVFAPVYVMFTKADLITGFTEFFSSSDKHEYDRVWGATLPYEPDDKRDVVAQFDTHFEELYEGLKEISVAQLSLSRGNQLSPGQLSFPLEFSTIKPSLRAFLATLFENNPFQYKPIFRGFYFTSALQEGETNSAAAQRIAHRFGLDGNALPKPHSAFSKNGFFLRDLFSKVIFADRQTVRQFASPTKTR
Transmembrane helix 444-466 LRYATFFGFVAALALALGGWTWS
Outside 467-1308 TIGNQQLVANVQADLDNVTRLQQGRNDLQSRLQAMDILEDRIEQLEQFRRDKPMSVSLGLYQGDRLEQHLLTEYYNGVRQILLAPVSQNLASFMKDVNAHPEQLVPMTRPPESGAVQGGTIPVSTNAAGTAPAASGTAPATAPQQAAAPQGGLYSDASPTNVQDAYNALKTYLMLSDKRHVEQAHLTDQLARFWRGWLETNRGNMPRDEMIRSAERMISFYLSRVNDNDWPMIDANLALVDQTRENLRRVVRGMPARQRVYEEIKARASTRFAPMTIARIVGDGNQGLVAGSYAIPGTFTREAWFDYVQPAIRDAATKELQAKDWVLNTSTQDDLTLEGSPEQIQKTLVGMYKTEYAQHWQKFMQGIAVQGFTSFGQAVDGMNRLGDPQDSPIRKILETAYDQTSWDNPSLANVTIKKAQTGVVNWVKQLFSRSQAGQVAAANIDINGNPAEVPMGPIGQEFVGLARIVATHDGTSMLKGYMESLSKVRTRFNVIKNQGDPGPGARQLMQQTLDGSGSELADSLKLVDEQMLTGLTDSQRKSLRPLLVRPLMQAFAVVIQPASAEVNKVWNAQVYQPFQSSLATKYPFAANAKVEAGAGEIAQVFGPDGSIAKFVGTTLGPLAVRRGDTLAARTWGDMGIGLTPDFTNGFARWVAPLAGGAAGSAAASAEPQTVFQILPQPSTGTTEYTIAIDGQQLRYRNTPPQWTNFVWPNPQGSPGATLSATTFDGRTVQLVNEPGRYGLEKLINSAQRKRRPDGTFDLTWAQGSVNVSVTMRIISTSQPSAGGGDQPQQQSLRGLQLPSSVADASAGAAQNATQAGTGTPGAAPAVAAANATNAQRAQ


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9979 - -


  Protein sequence: 1309 a.a.    

>T6CP015188 NZ_HG938370:c367838-363912 [Burkholderia cenocepacia H111] [TssM]
MQRILNVLTHPRTLSIVGIVALAAILFIVADMLQLPLLWAATAFAAILALWLVVALWRRWRVKRANQQLGQVLEEQAETG
KIAAPAAAALAPDAKTADLDVLRTRLSDAVKTIKTSKIGQVSGGSALYELPWYIVIGNPAAGKSSAVLNSGLQFPFADKN
SAVIHGIGGTRNCDWFFTTEGILLDTAGRYSVHEEDRSEWLGFLGLLKRYRPKAPINGIIVTASIAELTGNRPEFAINLA
KNLRQRVQELTEKLEVFAPVYVMFTKADLITGFTEFFSSSDKHEYDRVWGATLPYEPDDKRDVVAQFDTHFEELYEGLKE
ISVAQLSLSRGNQLSPGQLSFPLEFSTIKPSLRAFLATLFENNPFQYKPIFRGFYFTSALQEGETNSAAAQRIAHRFGLD
GNALPKPHSAFSKNGFFLRDLFSKVIFADRQTVRQFASPTKTRLRYATFFGFVAALALALGGWTWSTIGNQQLVANVQAD
LDNVTRLQQGRNDLQSRLQAMDILEDRIEQLEQFRRDKPMSVSLGLYQGDRLEQHLLTEYYNGVRQILLAPVSQNLASFM
KDVNAHPEQLVPMTRPPESGAVQGGTIPVSTNAAGTAPAASGTAPATAPQQAAAPQGGLYSDASPTNVQDAYNALKTYLM
LSDKRHVEQAHLTDQLARFWRGWLETNRGNMPRDEMIRSAERMISFYLSRVNDNDWPMIDANLALVDQTRENLRRVVRGM
PARQRVYEEIKARASTRFAPMTIARIVGDGNQGLVAGSYAIPGTFTREAWFDYVQPAIRDAATKELQAKDWVLNTSTQDD
LTLEGSPEQIQKTLVGMYKTEYAQHWQKFMQGIAVQGFTSFGQAVDGMNRLGDPQDSPIRKILETAYDQTSWDNPSLANV
TIKKAQTGVVNWVKQLFSRSQAGQVAAANIDINGNPAEVPMGPIGQEFVGLARIVATHDGTSMLKGYMESLSKVRTRFNV
IKNQGDPGPGARQLMQQTLDGSGSELADSLKLVDEQMLTGLTDSQRKSLRPLLVRPLMQAFAVVIQPASAEVNKVWNAQV
YQPFQSSLATKYPFAANAKVEAGAGEIAQVFGPDGSIAKFVGTTLGPLAVRRGDTLAARTWGDMGIGLTPDFTNGFARWV
APLAGGAAGSAAASAEPQTVFQILPQPSTGTTEYTIAIDGQQLRYRNTPPQWTNFVWPNPQGSPGATLSATTFDGRTVQL
VNEPGRYGLEKLINSAQRKRRPDGTFDLTWAQGSVNVSVTMRIISTSQPSAGGGDQPQQQSLRGLQLPSSVADASAGAAQ
NATQAGTGTPGAAPAVAAANATNAQRAQ*

  Nucleotide sequence: 3927 bp    

>T6CP015188 NZ_HG938370:c367838-363912 [Burkholderia cenocepacia H111] [TssM]
ATGCAACGCATCCTCAACGTGCTGACTCATCCGCGTACGCTCTCGATCGTCGGGATCGTCGCGCTAGCGGCCATTCTGTT
CATCGTCGCCGACATGTTGCAGCTGCCGCTCCTGTGGGCGGCGACCGCGTTCGCGGCGATCCTCGCGCTGTGGCTCGTGG
TCGCGCTGTGGCGCCGCTGGCGCGTGAAGCGTGCGAACCAGCAGCTCGGCCAGGTGCTGGAAGAGCAGGCGGAAACCGGC
AAGATCGCCGCGCCGGCCGCTGCCGCGCTCGCACCGGACGCGAAGACCGCCGACCTCGACGTGCTGCGCACGCGCCTGTC
GGATGCGGTGAAGACGATCAAGACGTCGAAGATCGGCCAGGTGTCGGGCGGCTCCGCGCTGTACGAACTGCCGTGGTACA
TCGTGATCGGCAACCCGGCCGCGGGCAAGAGCAGCGCCGTGCTCAATTCCGGTCTGCAGTTCCCGTTCGCGGACAAGAAC
AGCGCCGTGATCCACGGCATCGGCGGCACGCGCAACTGCGACTGGTTCTTCACGACCGAAGGGATCCTGCTCGACACGGC
CGGCCGCTATTCGGTGCACGAGGAAGACCGCAGCGAGTGGCTCGGCTTCCTCGGGCTGCTCAAGCGCTACCGTCCGAAGG
CGCCGATCAACGGCATCATCGTCACGGCCAGCATCGCCGAACTCACCGGCAACCGCCCCGAATTCGCGATCAACCTCGCG
AAGAACCTCCGTCAGCGCGTTCAGGAGCTGACGGAAAAGCTGGAAGTGTTCGCGCCGGTCTACGTGATGTTCACGAAGGC
CGACCTGATCACCGGCTTCACCGAATTCTTCAGCAGCAGCGACAAGCACGAGTACGACCGCGTGTGGGGCGCCACCCTGC
CCTACGAGCCCGACGACAAGCGCGACGTCGTCGCGCAGTTCGACACGCACTTCGAGGAACTCTACGAAGGGCTGAAGGAA
ATCAGCGTCGCGCAGCTGTCGCTGTCGCGCGGCAACCAGCTGTCGCCGGGCCAGTTGAGCTTCCCGCTCGAATTCTCGAC
GATCAAGCCGTCGCTGCGCGCGTTCCTCGCGACGCTGTTCGAGAACAACCCGTTCCAGTATAAGCCGATCTTCCGCGGCT
TCTACTTCACCAGCGCGCTGCAGGAAGGCGAAACCAACAGCGCGGCCGCGCAGCGCATCGCGCACCGCTTCGGCCTCGAC
GGGAATGCGCTGCCGAAACCGCACAGCGCGTTCTCGAAGAACGGCTTCTTCCTGCGCGACCTGTTCTCGAAGGTGATCTT
CGCGGACCGCCAGACGGTGCGCCAGTTCGCGAGCCCGACCAAGACGCGGCTGCGCTACGCGACCTTCTTCGGCTTCGTCG
CGGCGCTCGCGCTCGCGCTGGGCGGCTGGACCTGGTCGACGATCGGCAACCAGCAGCTGGTCGCGAACGTGCAGGCCGAC
CTCGACAACGTCACGCGCCTGCAGCAGGGCCGCAACGACCTGCAGTCGCGCCTGCAGGCGATGGACATCCTCGAGGACCG
GATCGAGCAGCTCGAACAGTTCCGCCGCGACAAGCCGATGTCGGTGTCGCTCGGCCTGTACCAGGGCGACCGGCTCGAGC
AGCATCTGCTGACCGAGTACTACAACGGCGTGCGCCAGATCCTGCTCGCGCCGGTCTCGCAAAACCTCGCGTCGTTCATG
AAGGATGTGAACGCGCACCCCGAGCAGCTCGTGCCGATGACGCGCCCGCCCGAATCGGGCGCCGTGCAGGGCGGCACGAT
ACCGGTCTCGACGAACGCGGCAGGCACCGCGCCGGCCGCGTCCGGCACCGCGCCGGCCACCGCACCGCAACAGGCGGCGG
CCCCGCAAGGCGGCCTCTACAGCGACGCGTCGCCAACCAACGTGCAGGATGCGTACAACGCGCTCAAGACGTACCTGATG
CTGTCCGACAAGCGTCACGTCGAACAGGCGCACCTGACCGACCAGCTCGCCCGCTTCTGGCGCGGCTGGCTCGAGACGAA
TCGCGGCAACATGCCGCGCGACGAGATGATCCGGAGCGCCGAGCGGATGATCTCGTTCTACCTGTCCCGCGTGAACGACA
ACGACTGGCCGATGATCGACGCGAACCTCGCGCTCGTCGACCAGACCCGCGAGAACCTGCGCCGCGTGGTGCGCGGCATG
CCGGCCCGCCAGCGCGTCTACGAGGAAATCAAGGCCCGCGCGTCGACCCGCTTCGCGCCGATGACCATCGCGCGCATCGT
CGGCGACGGCAACCAGGGGCTCGTGGCAGGCAGCTACGCGATTCCGGGCACGTTCACGCGTGAAGCGTGGTTCGACTACG
TGCAGCCGGCGATCCGCGATGCGGCGACCAAGGAGCTGCAGGCGAAGGACTGGGTGCTCAACACGTCGACGCAGGACGAC
CTGACGCTCGAGGGCAGCCCCGAGCAGATCCAGAAGACGCTCGTCGGCATGTACAAGACCGAGTACGCGCAGCACTGGCA
GAAGTTCATGCAGGGCATCGCGGTACAGGGCTTCACCAGCTTCGGCCAGGCCGTCGACGGGATGAACCGCCTCGGCGACC
CGCAGGATTCGCCGATCCGCAAGATCCTCGAGACCGCGTACGACCAGACGTCGTGGGACAACCCGTCGCTCGCGAACGTG
ACGATCAAGAAGGCGCAGACGGGCGTCGTGAACTGGGTCAAGCAGCTGTTCTCGCGCTCGCAGGCCGGCCAGGTGGCGGC
AGCCAACATCGACATCAACGGCAATCCGGCCGAGGTGCCGATGGGTCCGATCGGCCAGGAGTTCGTCGGGCTCGCGCGGA
TCGTCGCGACGCACGACGGCACGTCGATGCTGAAGGGCTACATGGAGTCGCTGTCGAAGGTCCGCACGCGCTTCAACGTG
ATCAAGAACCAGGGCGACCCGGGGCCGGGCGCGCGCCAGCTGATGCAGCAGACGCTCGACGGCAGCGGTTCGGAACTCGC
CGATTCGCTGAAGCTCGTCGACGAGCAGATGCTGACGGGCCTGACCGATTCGCAACGCAAGTCGCTGCGTCCGCTGCTGG
TGCGGCCGCTGATGCAGGCGTTCGCGGTCGTGATCCAGCCGGCCAGCGCCGAAGTCAACAAGGTGTGGAACGCGCAGGTC
TACCAGCCGTTCCAGAGCTCGCTCGCGACCAAGTACCCGTTCGCCGCGAACGCGAAGGTCGAGGCCGGCGCCGGCGAGAT
CGCGCAGGTGTTCGGTCCGGACGGCTCGATCGCGAAGTTCGTCGGCACGACGCTCGGGCCGCTCGCGGTGCGCCGCGGCG
ACACGCTCGCCGCCCGCACGTGGGGCGACATGGGCATCGGACTCACGCCGGACTTCACCAACGGCTTCGCCCGCTGGGTC
GCGCCGCTCGCGGGCGGCGCGGCCGGCAGCGCAGCCGCGTCGGCCGAGCCGCAGACCGTGTTCCAGATCCTGCCGCAACC
GAGCACGGGCACGACGGAATACACGATCGCGATCGACGGCCAGCAGCTGCGCTACCGCAACACGCCGCCGCAGTGGACCA
ACTTCGTGTGGCCGAACCCGCAGGGTTCGCCGGGCGCGACGCTGTCCGCGACGACCTTCGACGGCCGCACGGTGCAGCTC
GTCAACGAGCCGGGCCGCTACGGTCTCGAGAAGCTGATCAACTCGGCGCAGCGCAAGCGCCGTCCGGATGGCACCTTCGA
CCTGACGTGGGCACAGGGCAGCGTGAACGTGTCGGTGACGATGCGCATCATCAGCACGTCGCAGCCGTCGGCCGGTGGCG
GCGACCAGCCGCAGCAGCAAAGCCTGCGCGGCCTGCAGCTGCCGTCGTCGGTCGCCGACGCGAGCGCGGGCGCCGCGCAG
AACGCGACGCAAGCCGGCACCGGCACGCCGGGCGCCGCGCCGGCGGTCGCGGCCGCCAACGCAACGAATGCACAGAGGGC
GCAATGA