Detailed information of component protein


Summary

Component ID T6CP014268
Component protein type TssA
T6SS ID (Type) T6SS01112 experimental (Type i1)
Strain Vibrio cholerae strain A1552
Replicon chromosome
Sequence Protein sequence (421 a.a.); Nucleotide sequence (1263 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) VCA1552_RS14790
Coordinate (Strand) 136165..137427 (+)
NCBI ID WP_000073077.1
RefSeq NZ_CP024868
Uniprot ID A0A0X1L1P2_VIBCO, A0A0K9UV34_VIBCL, A0A023PRI8_VIBCL
KEGG ID vcq:EN18_04330
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
ImpA_N PF06812.14 1.3e-08 25..99
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-200 MSNVIFIDNVCYRLTNDSEEIRGLEPYAKVREEINRRFNPIAGGTDWAVVKEYCEQLACNQGMDFLICGYYAVACLKTQGLAGYATGMELMSASLANQGECDVKSAKVRKEILDWVNARVVQELKALKPTYESLRDLYRAERHCERLHQLFEQQQTEYKVDFEGVGFALFEHIDRIETQYHSLLKKQEKAQPPKLKFWQR
Transmembrane helix 201-223 GYALFTLGVLGVALGMVGGYWGW
Outside 224-420 PWFYTTPYAAPQRITTLNEASQTQALLNDSSTSERARWQHDLIPLYRDTLQQNLTISFSEPKRHAITQLNLLRTLYPENEQVNALSQEFALQQQQALEQTALFVAKFSEIRTKMANISLLAKRGKWAELEKQTKSLEEFAVSLSPIYGRVDYVQGLLEQGDVTNAQKEFAILKQRLDSLSWKIAELEQRIGDAALLQ


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9722 - -


  Protein sequence: 421 a.a.    

>T6CP014268 NZ_CP024868:136165-137427 [Vibrio cholerae] [TssA]
MSNVIFIDNVCYRLTNDSEEIRGLEPYAKVREEINRRFNPIAGGTDWAVVKEYCEQLACNQGMDFLICGYYAVACLKTQG
LAGYATGMELMSASLANQGECDVKSAKVRKEILDWVNARVVQELKALKPTYESLRDLYRAERHCERLHQLFEQQQTEYKV
DFEGVGFALFEHIDRIETQYHSLLKKQEKAQPPKLKFWQRGYALFTLGVLGVALGMVGGYWGWPWFYTTPYAAPQRITTL
NEASQTQALLNDSSTSERARWQHDLIPLYRDTLQQNLTISFSEPKRHAITQLNLLRTLYPENEQVNALSQEFALQQQQAL
EQTALFVAKFSEIRTKMANISLLAKRGKWAELEKQTKSLEEFAVSLSPIYGRVDYVQGLLEQGDVTNAQKEFAILKQRLD
SLSWKIAELEQRIGDAALLQ*

  Nucleotide sequence: 1263 bp    

>T6CP014268 NZ_CP024868:136165-137427 [Vibrio cholerae] [TssA]
ATGTCCAATGTGATTTTTATTGATAACGTTTGCTACCGATTAACCAATGATTCTGAGGAGATTCGCGGATTAGAGCCCTA
TGCGAAGGTTCGTGAGGAGATAAACCGCCGCTTCAATCCGATTGCTGGGGGCACGGATTGGGCAGTGGTAAAAGAGTACT
GTGAACAACTGGCCTGTAACCAAGGAATGGATTTTCTGATCTGCGGTTACTATGCGGTAGCCTGCCTGAAAACTCAGGGG
TTAGCGGGGTATGCCACCGGTATGGAGCTGATGAGTGCAAGCCTTGCCAACCAAGGTGAGTGTGATGTGAAAAGCGCCAA
AGTGCGCAAAGAGATCCTTGATTGGGTCAATGCACGTGTGGTGCAGGAACTGAAAGCACTTAAGCCAACTTATGAGTCGC
TGCGAGATCTGTATCGGGCTGAGCGCCATTGCGAGCGGTTACATCAGCTGTTTGAACAGCAACAAACCGAATACAAAGTA
GACTTTGAAGGGGTCGGGTTTGCTCTGTTTGAACACATAGACAGAATTGAAACCCAATACCACAGCTTATTGAAAAAGCA
GGAGAAGGCTCAGCCACCTAAGCTTAAGTTTTGGCAGCGCGGTTACGCGTTGTTCACTCTAGGTGTACTCGGGGTTGCAC
TGGGAATGGTGGGGGGCTACTGGGGGTGGCCTTGGTTTTATACCACGCCTTATGCCGCGCCACAGCGCATCACTACGTTG
AATGAGGCCTCTCAAACTCAAGCACTGCTCAACGACTCTTCCACAAGTGAGCGTGCGCGTTGGCAACATGATCTGATCCC
GCTGTATCGCGATACTTTGCAGCAGAATTTAACCATCTCGTTTAGTGAACCTAAGCGACATGCCATCACTCAGCTGAATC
TATTGCGCACTCTTTATCCTGAAAACGAGCAAGTGAATGCACTGAGTCAAGAGTTTGCCCTTCAGCAGCAACAAGCGTTG
GAGCAAACCGCGCTGTTCGTGGCTAAGTTCAGCGAAATTCGCACCAAAATGGCCAATATCTCGTTATTGGCTAAGCGAGG
GAAATGGGCTGAGTTAGAAAAGCAGACCAAATCATTAGAAGAGTTCGCGGTCAGCCTATCACCGATTTATGGTCGAGTTG
ACTATGTGCAAGGCCTCCTTGAACAGGGCGATGTCACAAATGCCCAGAAAGAGTTTGCGATCCTCAAACAAAGGCTAGAT
AGCCTAAGTTGGAAAATTGCCGAGCTTGAGCAGCGTATCGGCGATGCGGCTTTGTTGCAGTGA