Detailed information of component protein


Summary

Component ID T6CP012964
Component protein type TssM
T6SS ID (Type) T6SS00948 experimental (Type i1)
Strain Aeromonas hydrophila NJ-35
Replicon chromosome
Sequence Protein sequence (1162 a.a.); Nucleotide sequence (3486 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) U876_13515
Coordinate (Strand) 2948881..2952366 (-)
NCBI ID 827372796
GenBank CP006870
Uniprot ID UPI000588A010
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 3.9e-74 502..815
IcmF-related_N PF14331.8 1e-71 201..450
IcmF_C PF06744.14 5.1e-22 1034..1141
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-19 MFKTIFTFLRQQLPKLKPS
Transmembrane helix 20-39 WPLLGAVLWVLALILVWWLG
Outside 40-53 PRLEVHGAKPFEPL
Transmembrane helix 54-76 WGRVVFTLLWLWLLLGVVSWRVW
Inside 77-445 RKMQQLKAERQHEVVLEQDPVKGLIDRQALFLDRWLQALNTHLGKGALYAMPWYLVLGLPGSGKSSLIHRANPANKLNPRLDTELRDVAQDQLVDCWLGEQAVMLDPAGVLLSQSEAELDPQARKHERLWLHLLGWLNEHRRRQPLNGLVLTVDLAWLSHASVAERKAYAQLMRSRLQEVSATMNTRLPLYVAFTKLDLLRGFDVIYQQLDKEAREAVLGVTFKPGADWQQDLALFWDQWVDNLNQNLPELMLSRLDAAQRNALFSFVRQLAGLKDYVTSLLAETLAIEESKPLLVRGVYVSSVYQQGVPFDAFAQAASRRYNLPEPIHSALRGESNTYFVRQLFSSIIFPEAHLAGENRLHTLYRRRR
Transmembrane helix 446-468 MAIGLSCLSLFSAALIGGWHYFY
Outside 469-1161 RVNEEAGRNVLTKAQAFMETNEVADAHAFGVSQLPRLNLIREATLSFGNYRERMPLVADLGLYQGDEIGPYVEGSYLQLLSLRFLPAQMQGLLADLNQAPAGSEEKLAILRVMRMLDDASGRNKELVAQYMASRWQKAFPGQGAVQEQLMGHLDYALDHTNWYGARADRDQAAITAFVPFKEPVYGAQRELGKLPMYQRVYQNLVVKAGDVLPPDLNVRDEVGPTFDTVFALRSDNADQVPRLLTWPGFNDFFLKQDKALIDLTAMDAWVLGQRKLSQLSEADRKEITRQVNDRYVTDYVNQWQKLLTNLDVQTLESPEQALDVLAAITGNDQPFQRVLASLDDNTRIRKISDVEGDPAQAISARIGRPFMATNGALAGRGEQGPLIQEINQKLVELQHYLELIVNATEPGQSALKAVQLRMTNKYADPVFALQQYARSLPAPLDRWVGQLSEQSSRLVIDLAMSSLNQEWQDKVLTPFNSQLAGRYPFDPSSNKDVPLSEMERFFAPNGTLDSFYQVNLKPMVESGLMEGEFSSPIQAELVKQLDRAARIRQIFFSQQGNLEVQFALEPIELTANKRRSVLNLDGQLLEYAHGRRTKIPLVWPNTMRDGAESKITLVPAARERSPRNEGFVGPWAMFRLMDKGELTQVNDATFDVRFPVDQGAMTYRVYTDSAQNPFTGGLFSQFRLPESLY


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9946 - -


  Protein sequence: 1162 a.a.    

>T6CP012964 CP006870:c2952366-2948881 [Aeromonas hydrophila NJ-35] [TssM]
MFKTIFTFLRQQLPKLKPSWPLLGAVLWVLALILVWWLGPRLEVHGAKPFEPLWGRVVFTLLWLWLLLGVVSWRVWRKMQ
QLKAERQHEVVLEQDPVKGLIDRQALFLDRWLQALNTHLGKGALYAMPWYLVLGLPGSGKSSLIHRANPANKLNPRLDTE
LRDVAQDQLVDCWLGEQAVMLDPAGVLLSQSEAELDPQARKHERLWLHLLGWLNEHRRRQPLNGLVLTVDLAWLSHASVA
ERKAYAQLMRSRLQEVSATMNTRLPLYVAFTKLDLLRGFDVIYQQLDKEAREAVLGVTFKPGADWQQDLALFWDQWVDNL
NQNLPELMLSRLDAAQRNALFSFVRQLAGLKDYVTSLLAETLAIEESKPLLVRGVYVSSVYQQGVPFDAFAQAASRRYNL
PEPIHSALRGESNTYFVRQLFSSIIFPEAHLAGENRLHTLYRRRRMAIGLSCLSLFSAALIGGWHYFYRVNEEAGRNVLT
KAQAFMETNEVADAHAFGVSQLPRLNLIREATLSFGNYRERMPLVADLGLYQGDEIGPYVEGSYLQLLSLRFLPAQMQGL
LADLNQAPAGSEEKLAILRVMRMLDDASGRNKELVAQYMASRWQKAFPGQGAVQEQLMGHLDYALDHTNWYGARADRDQA
AITAFVPFKEPVYGAQRELGKLPMYQRVYQNLVVKAGDVLPPDLNVRDEVGPTFDTVFALRSDNADQVPRLLTWPGFNDF
FLKQDKALIDLTAMDAWVLGQRKLSQLSEADRKEITRQVNDRYVTDYVNQWQKLLTNLDVQTLESPEQALDVLAAITGND
QPFQRVLASLDDNTRIRKISDVEGDPAQAISARIGRPFMATNGALAGRGEQGPLIQEINQKLVELQHYLELIVNATEPGQ
SALKAVQLRMTNKYADPVFALQQYARSLPAPLDRWVGQLSEQSSRLVIDLAMSSLNQEWQDKVLTPFNSQLAGRYPFDPS
SNKDVPLSEMERFFAPNGTLDSFYQVNLKPMVESGLMEGEFSSPIQAELVKQLDRAARIRQIFFSQQGNLEVQFALEPIE
LTANKRRSVLNLDGQLLEYAHGRRTKIPLVWPNTMRDGAESKITLVPAARERSPRNEGFVGPWAMFRLMDKGELTQVNDA
TFDVRFPVDQGAMTYRVYTDSAQNPFTGGLFSQFRLPESLY*

  Nucleotide sequence: 3486 bp    

>T6CP012964 CP006870:c2952366-2948881 [Aeromonas hydrophila NJ-35] [TssM]
ATGTTCAAAACCATTTTTACTTTTCTGCGGCAACAGCTGCCGAAATTGAAACCCTCCTGGCCCCTGCTCGGTGCTGTGCT
CTGGGTGCTGGCTCTCATCCTGGTGTGGTGGCTGGGCCCTCGTCTCGAGGTGCACGGCGCCAAGCCGTTCGAGCCGCTGT
GGGGGCGGGTGGTGTTCACCCTGCTCTGGCTCTGGTTGCTGCTGGGAGTGGTCTCCTGGCGAGTGTGGCGCAAGATGCAA
CAGCTCAAGGCCGAGCGTCAGCACGAGGTAGTGCTGGAGCAGGACCCGGTCAAGGGGCTCATCGACAGGCAGGCGCTGTT
CCTCGATCGCTGGCTGCAGGCGTTGAATACCCATCTGGGCAAGGGGGCGCTCTACGCCATGCCCTGGTATCTGGTGCTGG
GGCTGCCCGGCAGCGGCAAGAGCAGCCTCATTCACCGCGCCAACCCGGCCAACAAGCTCAACCCGAGACTCGATACCGAA
CTGCGCGACGTGGCGCAGGATCAGCTGGTGGATTGCTGGTTGGGGGAACAGGCAGTGATGCTGGATCCCGCCGGGGTGCT
GCTCTCCCAGAGCGAAGCCGAACTGGATCCGCAGGCGCGCAAGCATGAGCGGCTCTGGCTGCACCTGCTTGGCTGGCTCA
ATGAACACCGCCGTCGCCAGCCCCTCAACGGCCTGGTGCTCACCGTGGATCTGGCCTGGCTCTCCCACGCCAGCGTGGCC
GAGCGCAAGGCCTATGCCCAGCTGATGCGCTCGCGCCTGCAGGAGGTGTCAGCCACCATGAATACCCGGTTGCCGCTCTA
TGTCGCCTTCACCAAGCTCGATCTGCTGCGCGGCTTTGACGTTATCTACCAGCAGCTCGACAAGGAGGCCCGCGAGGCCG
TGCTGGGGGTGACCTTCAAGCCGGGCGCCGACTGGCAGCAGGATCTGGCCCTGTTCTGGGATCAGTGGGTGGACAACCTC
AACCAGAATCTGCCCGAGCTGATGCTGAGCCGGCTCGATGCCGCCCAGCGCAACGCGCTGTTCTCGTTCGTGCGCCAGCT
GGCGGGCCTCAAGGATTACGTGACCAGCCTGCTGGCCGAGACCCTAGCCATCGAGGAGAGCAAGCCGCTCTTGGTACGCG
GGGTCTATGTCAGCTCCGTCTATCAGCAAGGGGTACCGTTCGATGCGTTTGCCCAGGCGGCCTCCCGCCGCTACAACCTG
CCAGAGCCCATCCACTCGGCCCTGCGCGGGGAGTCCAACACCTATTTCGTGCGCCAGCTGTTCTCCTCCATCATCTTCCC
GGAAGCCCATCTGGCCGGCGAGAACCGGCTGCATACCCTCTATCGCCGGCGCCGCATGGCCATCGGCCTCAGCTGCCTGT
CGCTCTTCTCGGCCGCCCTCATCGGTGGCTGGCACTACTTCTACCGGGTCAACGAGGAGGCGGGCCGCAACGTATTGACC
AAGGCTCAGGCCTTCATGGAGACCAACGAGGTGGCCGATGCCCACGCCTTCGGGGTGAGCCAGCTGCCGCGCCTCAACCT
CATTCGCGAGGCGACCCTCTCCTTTGGCAACTACCGCGAGCGGATGCCGCTGGTGGCCGACCTCGGCCTCTACCAGGGGG
ACGAGATCGGTCCTTATGTGGAAGGCTCCTACCTGCAGCTGCTGAGCCTGCGCTTCCTGCCGGCCCAGATGCAGGGATTG
CTGGCCGATCTCAACCAGGCGCCTGCCGGCAGCGAGGAGAAGCTCGCCATCCTGCGGGTGATGCGGATGCTGGACGATGC
GTCCGGTCGCAACAAGGAGCTGGTAGCGCAGTACATGGCAAGCCGCTGGCAGAAGGCCTTCCCGGGGCAGGGCGCGGTAC
AGGAACAGCTGATGGGGCACCTGGACTATGCCCTCGATCATACCAACTGGTATGGCGCCAGGGCCGATCGGGATCAGGCC
GCCATCACCGCCTTCGTGCCGTTCAAGGAGCCGGTCTACGGTGCCCAGCGCGAGCTCGGCAAGCTGCCCATGTATCAGCG
GGTCTACCAGAATCTGGTGGTGAAGGCGGGTGATGTATTGCCGCCGGATCTCAACGTGCGTGACGAGGTGGGTCCCACCT
TCGACACCGTGTTTGCCCTGCGCAGCGACAATGCCGACCAGGTGCCGCGGCTGCTCACCTGGCCCGGTTTCAACGACTTC
TTCCTGAAGCAAGACAAGGCGCTCATCGATCTCACCGCGATGGATGCCTGGGTGCTGGGCCAGCGCAAGCTGAGTCAGTT
GAGCGAGGCGGATCGCAAGGAGATCACCCGTCAGGTCAACGACCGCTACGTCACCGACTACGTCAACCAGTGGCAAAAAC
TGCTGACCAATCTGGACGTGCAGACCCTGGAGAGCCCGGAGCAGGCGCTCGACGTGCTCGCCGCCATCACCGGCAACGAT
CAGCCGTTCCAGCGGGTACTGGCCTCGCTGGATGACAACACCCGCATTCGCAAGATCTCCGACGTGGAAGGAGACCCGGC
CCAGGCCATCAGTGCCCGCATCGGTCGCCCCTTTATGGCCACTAATGGCGCATTGGCTGGCCGTGGCGAGCAGGGGCCGC
TCATTCAGGAGATCAATCAGAAGCTGGTGGAGCTGCAGCACTACCTGGAGCTCATCGTCAACGCCACCGAGCCGGGTCAG
TCCGCCTTGAAAGCGGTGCAGCTGCGCATGACCAACAAGTACGCCGATCCGGTGTTCGCCCTGCAGCAATATGCCCGCAG
TCTGCCGGCCCCGCTCGATCGCTGGGTGGGTCAACTCTCCGAGCAGAGCTCGCGGCTGGTGATCGACCTTGCCATGTCCT
CCCTCAATCAGGAGTGGCAGGACAAGGTGCTGACCCCCTTCAACAGCCAGCTGGCCGGCCGTTATCCGTTTGATCCGAGC
TCGAACAAGGACGTGCCCCTCTCCGAGATGGAGCGCTTCTTCGCACCTAACGGGACGCTGGACAGCTTCTATCAGGTCAA
CCTCAAGCCCATGGTGGAGAGCGGCCTGATGGAAGGGGAGTTCAGCTCGCCCATCCAGGCCGAGCTGGTCAAGCAGCTGG
ATCGTGCGGCCCGCATCCGCCAGATCTTCTTCAGCCAGCAGGGCAACCTGGAGGTGCAGTTCGCCCTTGAGCCCATCGAG
CTCACCGCCAACAAGCGGCGCAGTGTGCTGAACCTGGACGGCCAGTTGCTGGAATACGCCCATGGCCGCCGTACCAAGAT
CCCGCTGGTGTGGCCCAACACCATGCGCGACGGGGCCGAGAGCAAGATCACTCTGGTACCGGCCGCCCGCGAGCGTTCAC
CGCGCAACGAAGGCTTCGTCGGCCCCTGGGCCATGTTCCGCCTGATGGACAAGGGGGAGCTGACCCAGGTCAATGACGCC
ACTTTCGATGTGCGCTTCCCGGTGGATCAGGGGGCAATGACCTATCGCGTCTACACCGACAGCGCACAAAACCCCTTCAC
CGGCGGCCTGTTCAGCCAGTTCAGACTGCCCGAATCCCTCTATTGA