Detailed information of component protein


Summary

Component ID T6CP011987
Component protein type TagL
T6SS ID (Type) T6SS00548 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae HS11286
Replicon chromosome
Sequence Protein sequence (569 a.a.); Nucleotide sequence (1707 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KPHS_23010
Coordinate (Strand) 2330351..2332057 (+)
NCBI ID YP_005226601.1
RefSeq NC_016845
Uniprot ID A0A0H3GWJ1_KLEPH
KEGG ID kpm:KPHS_23010
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
OmpA PF00691.22 2.6e-16 438..534
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-8 MSPPQQRG
Transmembrane helix 9-28 LALWASLLSALVCLLFLPVP
Outside 29-31 RWG
Transmembrane helix 32-51 AWLILLVTLALIIGIWRIAS
Inside 52-317 RRTGRNVASTLAPLPEGAYRQPVVLVCGDLPCVWPQASPVRVVKQGCWIRVEKTEELQQVARQVLSQRPEWGPQLSVLLCVCPQRHAQSDALTSALLALRWQLSQLRQQTGYAVPLVLQGQVGSAMSRDLLWQAAIPGEAVKVWQPSCAPCSVPAWVSAGGAAALEQQVLMNSLMGWFEQHVHAVLTEENTDLPPLTPAAVLWGLGPSLPGRLASSAWTTWLSRHSGLSRVAGWQPDESDTGDASALPELILPQLPVGRGLTPRGR
Transmembrane helix 318-340 AWRAALAIFTLAAVAALLSSGWN
Outside 341-568 NRQLLQRVSVDIARYERIAMDDYRPKASAVRVLREDAALLDSWARNGVPLRLSLGLYHGEQIRLPLLEAIRGYVPPPPPPRPVQRVAPDVIRLDSMSLFDTGKWVLKPGSTKRLVSSLMDIKARPGWLIVVAGHTDSVGEEKANQLLSLKRAESVRDWMRDTGDVPDSCFAVQGYGESRPIATNDTPEGRALNRRVEISLVPQVDACRLPDQPSASSQDDGASLHNGE


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9907 - -


  Protein sequence: 569 a.a.    

>T6CP011987 NC_016845:2330351-2332057 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TagL]
MSPPQQRGLALWASLLSALVCLLFLPVPRWGAWLILLVTLALIIGIWRIASRRTGRNVASTLAPLPEGAYRQPVVLVCGD
LPCVWPQASPVRVVKQGCWIRVEKTEELQQVARQVLSQRPEWGPQLSVLLCVCPQRHAQSDALTSALLALRWQLSQLRQQ
TGYAVPLVLQGQVGSAMSRDLLWQAAIPGEAVKVWQPSCAPCSVPAWVSAGGAAALEQQVLMNSLMGWFEQHVHAVLTEE
NTDLPPLTPAAVLWGLGPSLPGRLASSAWTTWLSRHSGLSRVAGWQPDESDTGDASALPELILPQLPVGRGLTPRGRAWR
AALAIFTLAAVAALLSSGWNNRQLLQRVSVDIARYERIAMDDYRPKASAVRVLREDAALLDSWARNGVPLRLSLGLYHGE
QIRLPLLEAIRGYVPPPPPPRPVQRVAPDVIRLDSMSLFDTGKWVLKPGSTKRLVSSLMDIKARPGWLIVVAGHTDSVGE
EKANQLLSLKRAESVRDWMRDTGDVPDSCFAVQGYGESRPIATNDTPEGRALNRRVEISLVPQVDACRLPDQPSASSQDD
GASLHNGE*

  Nucleotide sequence: 1707 bp    

>T6CP011987 NC_016845:2330351-2332057 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TagL]
ATGAGCCCCCCGCAGCAGCGTGGGCTGGCGCTGTGGGCCAGTCTGCTGAGTGCGCTGGTGTGCCTGCTATTTTTGCCGGT
TCCCCGCTGGGGGGCGTGGCTCATTCTGCTGGTCACGCTGGCCCTGATCATCGGGATCTGGCGCATCGCCAGTCGTCGTA
CCGGACGTAACGTCGCATCAACCCTGGCCCCTCTCCCGGAGGGCGCTTATCGCCAACCGGTGGTCCTCGTTTGCGGCGAC
CTGCCGTGTGTCTGGCCGCAAGCGTCACCGGTGCGAGTGGTCAAACAGGGCTGCTGGATCCGCGTGGAAAAGACGGAGGA
GCTGCAGCAGGTCGCGCGCCAGGTATTGAGCCAGCGGCCGGAATGGGGGCCTCAGCTGTCGGTGCTGCTCTGCGTCTGCC
CGCAGCGGCATGCGCAAAGCGATGCGCTGACCAGCGCTCTGCTGGCCCTGCGCTGGCAACTCAGCCAGCTGCGCCAGCAG
ACGGGGTATGCCGTACCGCTGGTGCTGCAGGGGCAGGTGGGCAGCGCGATGAGTCGCGACCTGTTGTGGCAGGCGGCGAT
ACCGGGTGAAGCGGTGAAAGTCTGGCAGCCCTCCTGCGCCCCCTGTTCCGTACCGGCCTGGGTAAGCGCCGGTGGGGCGG
CCGCGCTGGAGCAGCAGGTGCTGATGAACAGCCTGATGGGCTGGTTTGAACAGCACGTCCATGCCGTGTTGACGGAAGAG
AATACCGACCTGCCACCTCTGACCCCTGCGGCCGTGCTGTGGGGCCTCGGGCCCTCGCTGCCTGGAAGGCTGGCATCGTC
GGCCTGGACGACGTGGTTATCCCGACATAGCGGCCTGTCGCGGGTAGCTGGCTGGCAGCCAGATGAGAGCGACACCGGGG
ACGCTTCAGCTTTGCCGGAATTAATCCTGCCGCAGTTACCGGTGGGACGGGGACTCACGCCACGAGGCAGGGCCTGGCGA
GCGGCGCTCGCGATTTTCACCCTCGCGGCTGTCGCCGCGCTGCTCAGCAGTGGCTGGAACAATCGACAACTGCTGCAGCG
CGTGAGCGTCGATATTGCCCGTTATGAGCGGATTGCGATGGATGATTATCGACCAAAAGCCAGCGCTGTCAGGGTGCTGC
GTGAAGATGCCGCGCTGCTTGATAGCTGGGCGCGTAACGGCGTCCCGCTGCGCCTGAGTCTGGGCTTGTATCACGGGGAG
CAGATTCGCCTGCCGTTGCTGGAGGCGATTCGCGGTTACGTGCCGCCTCCGCCTCCGCCCAGGCCGGTGCAGCGCGTCGC
GCCGGATGTCATCCGCCTTGACAGCATGTCGCTATTCGATACCGGGAAATGGGTACTGAAGCCTGGTTCGACAAAGCGGC
TGGTCAGCTCGCTGATGGACATTAAGGCCAGGCCCGGGTGGCTGATCGTGGTGGCGGGTCACACCGACAGCGTGGGTGAG
GAAAAAGCCAACCAGCTATTGTCGCTGAAACGTGCGGAATCGGTCCGCGACTGGATGCGCGATACCGGCGACGTGCCGGA
CAGCTGCTTTGCCGTTCAGGGCTATGGCGAAAGCCGACCAATTGCAACAAACGATACGCCGGAAGGCCGTGCGCTGAACC
GTCGTGTCGAAATCAGTCTGGTGCCGCAGGTAGACGCCTGCCGGTTACCGGACCAACCCTCTGCGTCATCCCAGGATGAT
GGCGCTTCACTACACAATGGAGAGTAA