Detailed information of component protein


Summary

Component ID T6CP011754
Component protein type TagL
T6SS ID (Type) T6SS00344 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
Replicon chromosome
Sequence Protein sequence (569 a.a.); Nucleotide sequence (1707 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KP1_RS11240
Coordinate (Strand) 2302974..2304680 (+)
NCBI ID WP_014907726.1
RefSeq NC_012731
Uniprot ID A0A652Q1A0_9ENTR, A0A332LZR6_KLEPN, A0A3F3BGB9_KLEPN
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
OmpA PF00691.22 2.6e-16 438..534
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-8 MSPAQQRG
Transmembrane helix 9-28 LALWASLLSALVCLLFLPVP
Outside 29-31 RWG
Transmembrane helix 32-51 AWLILLVTLALIIGIWRIAS
Inside 52-316 RRTGRNVASTLAPLPEGAYRQPVVLVCGDLPCVWPPASPVRVVKQGCWIRVEKTEDLQQVARQVLSQRPEWGPQLSVLLCVCPQRHAQSDALTSALLALRWQLSQLRQQTGYAVPLALQGQVGSAMSRDLLWQAAIPGEAVKVWQPSCAPCSVPAWVSAGGAAALEQQVLMNSLMGWFEQHVHAVLTEENTDLPPLPPAAVLWGLGPSLPGSLASSAWTTWLSRHSGLSRVAGWQPGESDTGDASALPEFILPQLPAGRGLTPRG
Transmembrane helix 317-339 WAWRAALAIFTLAAVAALLSSGW
Outside 340-568 NNRQLLQRVGVDIARYERIAMDDYRPKASAVRVLREDAALLDSWARNGVPLRLSLGLYHGEQIRLPLLEAIRGYVPPPPPPRPVQHVAPDVIRLDSMSLFDTGKWVLKPGSTKRLVSSLMDIKARPGWLIVVAGHTDSVGEEKANQLLSLKRAESVRDWMRDTGDVPDSCFAVQGYGESRPIATNDTPEGRALNRRVEISLVPQVDACRLPDQPSASSQDDGASLHNGE


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9893 - -


  Protein sequence: 569 a.a.    

>T6CP011754 NC_012731:2302974-2304680 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TagL]
MSPAQQRGLALWASLLSALVCLLFLPVPRWGAWLILLVTLALIIGIWRIASRRTGRNVASTLAPLPEGAYRQPVVLVCGD
LPCVWPPASPVRVVKQGCWIRVEKTEDLQQVARQVLSQRPEWGPQLSVLLCVCPQRHAQSDALTSALLALRWQLSQLRQQ
TGYAVPLALQGQVGSAMSRDLLWQAAIPGEAVKVWQPSCAPCSVPAWVSAGGAAALEQQVLMNSLMGWFEQHVHAVLTEE
NTDLPPLPPAAVLWGLGPSLPGSLASSAWTTWLSRHSGLSRVAGWQPGESDTGDASALPEFILPQLPAGRGLTPRGWAWR
AALAIFTLAAVAALLSSGWNNRQLLQRVGVDIARYERIAMDDYRPKASAVRVLREDAALLDSWARNGVPLRLSLGLYHGE
QIRLPLLEAIRGYVPPPPPPRPVQHVAPDVIRLDSMSLFDTGKWVLKPGSTKRLVSSLMDIKARPGWLIVVAGHTDSVGE
EKANQLLSLKRAESVRDWMRDTGDVPDSCFAVQGYGESRPIATNDTPEGRALNRRVEISLVPQVDACRLPDQPSASSQDD
GASLHNGE*

  Nucleotide sequence: 1707 bp    

>T6CP011754 NC_012731:2302974-2304680 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TagL]
ATGAGCCCCGCGCAGCAGCGTGGGCTGGCGCTGTGGGCCAGTCTGCTGAGTGCGCTGGTGTGCCTGCTATTTTTGCCGGT
TCCCCGCTGGGGGGCGTGGCTCATTCTGCTGGTCACGCTGGCCCTGATCATCGGGATCTGGCGCATCGCCAGTCGTCGTA
CCGGACGTAACGTCGCATCAACCCTGGCCCCTCTCCCGGAGGGCGCTTATCGCCAGCCGGTGGTCCTCGTTTGCGGCGAC
CTGCCGTGTGTCTGGCCGCCAGCGTCACCGGTGCGAGTCGTCAAACAGGGCTGCTGGATCCGCGTGGAAAAGACGGAGGA
TCTGCAGCAGGTCGCGCGCCAGGTATTGAGCCAGCGGCCGGAATGGGGGCCTCAGCTGTCGGTGCTGCTCTGCGTCTGCC
CGCAGCGGCATGCGCAAAGCGATGCGCTGACCAGCGCTCTGCTGGCCCTGCGCTGGCAACTCAGCCAGCTGCGTCAGCAG
ACGGGGTATGCCGTACCGCTGGCGCTGCAGGGGCAGGTGGGCAGCGCGATGAGTCGCGACCTGTTGTGGCAGGCGGCGAT
ACCGGGTGAAGCGGTGAAAGTCTGGCAGCCCTCCTGCGCCCCCTGTTCCGTACCGGCCTGGGTAAGCGCCGGCGGGGCGG
CCGCGCTGGAGCAGCAGGTGCTGATGAACAGCCTGATGGGCTGGTTTGAACAGCACGTCCATGCCGTGTTGACGGAAGAG
AATACCGACCTGCCACCTCTGCCCCCTGCGGCCGTGCTGTGGGGCCTCGGGCCCTCGCTGCCTGGAAGTCTGGCATCGTC
GGCCTGGACGACGTGGTTATCCCGACATAGCGGCCTGTCGCGGGTAGCTGGCTGGCAGCCTGGCGAGAGCGACACCGGGG
ACGCTTCAGCTTTGCCGGAATTCATCCTGCCGCAGTTACCGGCGGGACGGGGACTCACGCCACGAGGCTGGGCCTGGCGC
GCGGCGCTCGCGATTTTCACCCTCGCGGCTGTCGCCGCGCTGCTCAGCAGTGGCTGGAACAATCGACAACTGCTGCAGCG
CGTGGGCGTCGATATTGCCCGTTATGAGCGGATTGCGATGGATGATTATCGACCAAAAGCCAGCGCTGTCAGGGTGCTGC
GTGAAGATGCCGCGCTGCTCGATAGCTGGGCGCGTAACGGCGTCCCGCTGCGCCTGAGTCTGGGCTTGTATCACGGGGAG
CAGATTCGCCTGCCGTTGCTGGAGGCGATTCGCGGTTACGTGCCGCCTCCGCCTCCGCCCAGGCCGGTGCAGCACGTCGC
GCCGGATGTCATCCGCCTTGACAGCATGTCGCTATTCGATACCGGGAAATGGGTACTGAAGCCTGGTTCGACAAAGCGGC
TGGTCAGCTCGCTGATGGACATTAAGGCCAGGCCCGGGTGGCTGATCGTGGTGGCGGGTCACACCGACAGCGTGGGTGAG
GAAAAAGCCAACCAGCTATTGTCGCTGAAACGTGCCGAATCGGTCCGCGACTGGATGCGCGATACCGGCGACGTGCCGGA
CAGCTGCTTTGCCGTTCAGGGCTATGGCGAAAGCCGACCAATTGCAACAAACGATACGCCGGAAGGCCGTGCGCTGAACC
GTCGTGTCGAAATCAGTCTGGTGCCGCAGGTAGACGCCTGCCGGTTACCGGACCAACCCTCTGCGTCATCCCAGGATGAT
GGCGCTTCACTACACAATGGAGAGTAA