SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP011590
Component protein type	FHA
T6SS ID (Type)	T6SS00208 (Type i1)
Strain	Vibrio cholerae O395
Replicon	chromosome I
Sequence	Protein sequence (496 a.a.); Nucleotide sequence (1488 bp)
Reference	[1] Bernard CS, Brunet YR, Gavioli M, et al. Regulation of type VI secretion gene clusters by sigma54 and cognate enhancer binding proteins. J Bacteriol. 2011 May;193(9):2158-67. doi: 10.1128/JB.00029-11. Epub 2011 Mar 4. PMID: 21378190

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	VC0395_RS00135
Coordinate (Strand)	29143..30630 (-)
NCBI ID	WP_001089706.1
RefSeq	NC_009456
Uniprot ID	A0A0H3AG71_VIBC3, A0A023PRJ4_VIBCL
KEGG ID	vco:VC0395_0026
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
FHA	PF00498.28	2.8e-05	35..102

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
		-	-

Protein sequence: 496 a.a.

						>T6CP011590 NC_009456:c30630-29143 [Vibrio cholerae O395] [FHA]
MNSVTLPSLTLLVTNAQHLESGLSAQHTWTSSGGVIGSSPNAQWRLVDAQGSVKPMHCEVMMVDGAYCLKDSCGSTYVNG
ADMPLGVGQMARLTHKDEVSVGPYRLRVLFGNAIEVEEQYGSLDALFASKDEDLLADLTLDIEPEKHELPTNTDPLQALD
NLMGAAGSSTSLLDDPKSEQPLSAQPSLVPQDNLVLQNADFTPQADSEYEMTSSIRLKKILGFAKATFAKQTKSEAPNVT
SATPTISQYKTSESNVSEGFTMDEKVLDLLEEEVAKSFQPQLEKSAYSTMHTSSTSQANHLVTGPILEGLGVDLSDENDM
NRMHLLSQELGESLQACVRGLLDLHQQVSESRFGTLNRNLQPIEDNPLRLGLSYEKTIRTLYDADKSVVHLSAPAAIAES
LKTVRDHNEAMQFATSEALSQILNAFSPQVMLRRFHHYKRNSDTTQTSTDAWAWNMYCSYYQELTSNRQRGFEKLFWEIF
EQAYDRKIREKQLEL*					

Nucleotide sequence: 1488 bp

						>T6CP011590 NC_009456:c30630-29143 [Vibrio cholerae O395] [FHA]
ATGAACTCAGTGACATTACCTTCGTTGACCCTATTAGTCACCAATGCTCAGCACTTAGAGTCTGGCTTGTCCGCTCAGCA
TACGTGGACCTCGTCAGGTGGGGTGATCGGCTCATCGCCGAATGCGCAGTGGCGTTTGGTCGATGCGCAAGGCAGTGTAA
AACCCATGCACTGTGAAGTGATGATGGTAGACGGGGCGTATTGTTTAAAAGACAGCTGCGGCAGCACGTATGTCAACGGG
GCAGACATGCCACTGGGCGTTGGGCAAATGGCACGTCTGACTCACAAAGATGAAGTGAGTGTGGGGCCTTACCGTTTGCG
AGTGCTGTTTGGTAACGCCATCGAAGTGGAAGAACAATATGGATCTTTAGATGCGCTGTTTGCCTCTAAGGATGAGGATC
TGCTAGCGGATTTGACGCTCGACATCGAACCAGAAAAACACGAATTACCAACCAATACAGACCCATTACAGGCGCTCGAT
AACCTGATGGGTGCGGCGGGCAGTTCGACCTCCTTACTGGATGATCCTAAAAGTGAGCAGCCGTTATCCGCCCAACCTAG
CCTCGTGCCACAAGATAACTTAGTGCTGCAAAATGCCGATTTTACGCCACAAGCGGACAGTGAGTATGAGATGACCTCAT
CGATCCGCCTTAAGAAAATTCTTGGTTTTGCGAAGGCCACCTTTGCTAAGCAAACCAAATCAGAAGCACCGAACGTGACT
TCTGCCACCCCCACAATTTCTCAATATAAAACCAGCGAAAGCAACGTATCAGAGGGCTTCACAATGGATGAAAAAGTACT
GGATTTGTTAGAAGAGGAAGTCGCGAAAAGTTTCCAACCGCAGTTGGAGAAAAGCGCGTATTCCACTATGCACACAAGCT
CAACCAGCCAAGCTAACCACTTGGTGACAGGTCCGATCTTGGAAGGGCTCGGCGTAGACCTGAGTGATGAAAATGATATG
AATCGTATGCATCTTTTATCGCAAGAGCTGGGTGAGTCTTTGCAAGCTTGTGTGCGCGGTTTACTCGATTTGCATCAACA
AGTGAGTGAAAGCCGTTTCGGTACTTTGAACCGTAATCTGCAACCCATTGAAGATAACCCGCTGCGTTTAGGCCTCTCCT
ATGAAAAGACGATCCGCACTCTGTACGATGCTGATAAGAGCGTCGTGCACCTTTCTGCCCCTGCGGCGATTGCTGAAAGC
CTAAAAACCGTTCGCGATCATAATGAAGCGATGCAGTTCGCCACGTCAGAAGCCTTGAGCCAAATTCTCAACGCTTTCTC
ACCACAGGTGATGCTGCGCCGTTTCCACCACTACAAGCGCAATTCTGATACCACACAAACTTCCACGGATGCTTGGGCGT
GGAATATGTACTGCAGCTACTACCAAGAGCTGACCTCTAACCGCCAACGCGGCTTTGAGAAGTTGTTTTGGGAGATCTTT
GAGCAAGCCTACGATCGCAAAATTCGCGAGAAGCAACTGGAGCTATAA					