Detailed information of component protein


Summary

Component ID T6CP011511
Component protein type TssH
T6SS ID (Type) T6SS00126 experimental (Type i4b)
Strain Burkholderia cenocepacia AU 1054
Replicon chromosome I
Sequence Protein sequence (889 a.a.); Nucleotide sequence (2668 bp)
Reference
[1] Boyer F, Fichant G, Berthod J, et al. Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources? BMC Genomics. 2009 Mar 12;10:104. doi: 10.1186/1471-2164-10-104. PMID: 19284603
[2] Perault AI, Chandler CE, Rasko DA, et al. Host Adaptation Predisposes Pseudomonas aeruginosa to Type VI Secretion System-Mediated Predation by the Burkholderia cepacia Complex. Cell Host Microbe. 2020 Oct 7;28(4):534-547.e3. doi: 10.1016/j.chom.2020.06.019. Epub 2020 Aug 4. PMID: 32755549
[3] Loeven NA, Perault AI, Cotter PA, et al. The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection. mBio. 2021 Oct 26;12(5):e0209821. doi: 10.1128/mBio.02098-21. Epub 2021 Sep 28. PMID: 34579569
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) BCEN_RS13120
Coordinate (Strand) 2897679..2900346 (-)
NCBI ID WP_009967199.1
RefSeq NC_008060
Uniprot ID A0A1X4K385_BURPE
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Clp_N PF02861.22 2.7e-08 23..74
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-888 MSTPLKTLITKLNPLCRHATERAASACLARGHYEVDLEHLFLALLDEATGDLPLALRASRVDPHALHADLERELTRLKTGNTRTPVFSVHLIALFEQAWLIASLDSQLGRIRSGRLLLALLTAPDLAQFAQRMSSRFAEMNVTDLKHKFDEIMAGSSEAEPRQADDDGSDVAPAADGFAPAAGPSKTPALDTYTTNLTQRARRQDRPGDRPRSGDPPGDRHPDAPPPEQPDHDRRGRRRQNGGRRRARAADRGRRRAAAAARRRAARARHGAAAGRREREGRVREPAEERDRRGEEERAPDHPVHRRGAHDHRRGRPGRPERCGEPAEARTRARRAAHDRRDDVERIQEVLREGCGARAAFPGREGRGAERAAGRRDAARDVGPDGEALQRADSRRCDHGGRAPVAPLHQRPPAAGQGDQRARYRLREGRARAQRDAGRDRRYEEAHRAHRCGNRVAGARGGGRRGARRAARRAARRARHGARTTGEG*GTLRSRARDRRRDHRAARCARPRTRPVGGRPAGRRAGHSRETRRTRRGAARAAGRRADGAAAGRRPRRRRDRRRVDGHSARPDGEGRDRHRAEPAAAADRTRDRPGSCAGGDRPACAHRDREPRGPEQAARRVHVRRAVGRRQDRDGAGAGRHPVRRRAQDGHDQHERVPGSAQRVGPEGVAAGLRRLRRRRRADRGRASQPVFRRAARRGREGAPGRARDVLPGVRQGHDGRCGRARDRLPQHADHPDVERRLGRGNAGLPEQAGRGAARSGRACRGAAPAAVQDLQAGVPRPDEGRAVLPDFRRRAGRDHRAEARTHPPPDRGEPQGRVRVGRVARRRGARTLHRGRLGRPQRRPHPERHAAAGDRGPRARPDRRRRGDRAHRGARGRGRRIRVHRR


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9935 - -


  Protein sequence: 889 a.a.    

>T6CP011511 NC_008060:c2900346-2897679 [Burkholderia cenocepacia AU 1054] [TssH]
MSTPLKTLITKLNPLCRHATERAASACLARGHYEVDLEHLFLALLDEATGDLPLALRASRVDPHALHADLERELTRLKTG
NTRTPVFSVHLIALFEQAWLIASLDSQLGRIRSGRLLLALLTAPDLAQFAQRMSSRFAEMNVTDLKHKFDEIMAGSSEAE
PRQADDDGSDVAPAADGFAPAAGPSKTPALDTYTTNLTQRARRQDRPGDRPRSGDPPGDRHPDAPPPEQPDHDRRGRRRQ
NGGRRRARAADRGRRRAAAAARRRAARARHGAAAGRREREGRVREPAEERDRRGEEERAPDHPVHRRGAHDHRRGRPGRP
ERCGEPAEARTRARRAAHDRRDDVERIQEVLREGCGARAAFPGREGRGAERAAGRRDAARDVGPDGEALQRADSRRCDHG
GRAPVAPLHQRPPAAGQGDQRARYRLREGRARAQRDAGRDRRYEEAHRAHRCGNRVAGARGGGRRGARRAARRAARRARH
GARTTGEG*GTLRSRARDRRRDHRAARCARPRTRPVGGRPAGRRAGHSRETRRTRRGAARAAGRRADGAAAGRRPRRRRD
RRRVDGHSARPDGEGRDRHRAEPAAAADRTRDRPGSCAGGDRPACAHRDREPRGPEQAARRVHVRRAVGRRQDRDGAGAG
RHPVRRRAQDGHDQHERVPGSAQRVGPEGVAAGLRRLRRRRRADRGRASQPVFRRAARRGREGAPGRARDVLPGVRQGHD
GRCGRARDRLPQHADHPDVERRLGRGNAGLPEQAGRGAARSGRACRGAAPAAVQDLQAGVPRPDEGRAVLPDFRRRAGRD
HRAEARTHPPPDRGEPQGRVRVGRVARRRGARTLHRGRLGRPQRRPHPERHAAAGDRGPRARPDRRRRGDRAHRGARGRG
RRIRVHRRM

  Nucleotide sequence: 2668 bp    

>T6CP011511 NC_008060:c2900346-2897679 [Burkholderia cenocepacia AU 1054] [TssH]
ATGAGCACGCCTCTGAAGACCCTGATCACGAAACTGAACCCGCTGTGCCGCCACGCGACCGAGCGTGCGGCGAGCGCGTG
CCTGGCGCGCGGCCACTACGAGGTCGATCTGGAGCATCTGTTCCTCGCGTTGCTCGACGAAGCGACGGGCGATCTGCCGC
TCGCCTTGCGCGCGAGCCGCGTCGATCCGCATGCGCTGCACGCCGATCTCGAACGCGAGCTCACGCGCCTGAAGACGGGC
AACACGCGCACGCCGGTGTTCTCCGTGCATCTGATCGCGCTGTTCGAGCAGGCGTGGCTGATCGCGTCGCTCGATTCGCA
GCTCGGCCGCATCCGTTCCGGGCGCCTGCTGCTCGCGCTGCTGACCGCGCCGGATCTCGCGCAGTTCGCGCAACGGATGT
CGTCGCGCTTCGCGGAAATGAACGTGACGGACCTGAAGCACAAGTTCGACGAAATCATGGCCGGTTCGAGCGAAGCCGAG
CCGCGCCAGGCGGACGACGACGGCAGCGACGTCGCGCCGGCCGCCGACGGCTTTGCGCCCGCGGCTGGCCCATCGAAGAC
GCCCGCGCTCGACACCTATACGACCAACCTCACGCAGCGCGCGCGACGGCAAGATCGACCCGGTGATCGGCCGCGAAGCG
GAGATCCGCCAGGCGATCGACATCCTGATGCGCCGCCGCCAGAACAACCCGATCATGACCGGCGAGGCCGGCGTCGGCAA
AACGGCGGTCGTCGAAGGGCTCGCGCTGCGGATCGCGGCCGACGACGTGCCGCCGCCGCTGCGCGGCGTCGCGCTGCACG
TGCTCGACATGGGGCTGCTGCAGGCCGGCGCGAGCGTGAAGGGCGAGTTCGAGAACCGGCTGAAGAGCGTGATCGACGAG
GTGAAGAAGAGCGCGCACCCGATCATCCTGTTCATCGACGAGGCGCACACGATCATCGGCGCGGGCGGCCAGGCCGGCCA
GAACGATGCGGCGAACCTGCTGAAGCCCGCACTCGCGCGCGGCGAGCTGCGCACGATCGCCGCGACGACGTGGAGCGAAT
ACAAGAAGTACTTCGAGAAGGATGCGGCGCTCGCGCGGCGTTTCCAGGTCGTGAAGGTCGAGGAGCCGAGCGAGCCGCTG
GCCGCCGCGATGCTGCGCGGGATGTCGGGCCTGATGGAGAAGCACTTCAACGTGCGGATTCTCGACGATGCGATCACGGA
GGCCGTGCGCCTGTCGCACCGCTACATCAGCGGCCGCCAGCTGCCGGACAAGGCGATCAGCGTGCTCGATACCGCCTGCG
CGAAGGTCGCGCTCGCGCACAGCGCGACGCCGGCCGCGATCGACGATACGAAGAAGCGCATCGAGCGCATCGATGCGGAA
ATCGCGTCGCTGGAGCGCGAGGCGGCGGGCGGCGCGGCGCACGACGAGCGGCTCGGCGAGCTGCGCGGCGCGCGCGACAC
GGCGCTCGAACAACTGGCGAAGGATGAGGAACGCTACGAAGCCGAGCGCGTGATCGTCGCCGAGATCACCGAGCTGCGCG
ATGCGCTCGACCGCGCACGCGGCCCGTCGGAGGACGGCCAGCCGGTCGACGTGCAGGCCACTCGCGAGAAACTCGCCGAA
CGCGTCGCGGCGCTGCACGCGCTGCAGGGCGGCGAGCCGATGGTGCCGCTGCAGGTCGACGGCCACGTCGTCGCCGAGAT
CGTCGCCGCGTGGACGGGCATTCCGCTCGGCCGGATGGTGAAGGACGAGATCGACACCGTGCTGAACCTGCAGCCGCTGC
TGACCGCACGCGTGATCGGCCAGGATCATGCGCTGGAGGCGATCGCCCAGCGTGTGCGCACCGCGACCGCGAACCTCGAG
GACCCGAACAAGCCGCGCGGCGTGTTCATGTTCGTCGGGCCGTCGGGCGTCGGCAAGACCGAGACGGCGCTGGCGCTGGC
CGACATCCTGTACGGCGGCGAGCGCAAGATGGTCACGATCAACATGAGCGAGTACCAGGAAGCGCACAGCGTGTCGGGCC
TGAAGGGGTCGCCGCCGGGCTACGTCGGTTACGGCGAAGGCGGCGTGCTGACCGAGGCCGTGCGTCGCAACCCGTATTCC
GTCGTGCTGCTCGACGAGGTCGAGAAGGCGCACCCGGACGTGCTCGAGATGTTCTTCCAGGTGTTCGACAAGGGCACGAT
GGACGATGCGGAAGGGCGCGAGATCGACTTCCGCAACACGCTGATCATCCTGACGTCGAACGTCGGCTCGGCCGCGGTAA
TGCAGGCCTGCCTGAACAAGCCGGCCGAGGAGCTGCCCGATCCGGACGCGCTTGCCGAGGCGCTGCGCCCGCAGCTGTAC
AAGACCTTCAAGCCGGCGTTCCTCGGCCGGATGAAGGTCGTGCCGTACTACCCGATTTCCGACGACGTGCTGGCCGAGAT
CATCGAGCTGAAGCTCGAACGCATCCGCCGCCGGATCGAGGCGAACCACAAGGCCGCGTTCGAGTGGGACGAGTCGCTCG
TCGACGCGGTGCTCGCACGCTGCACCGAGGTCGACTCGGGCGCCCGCAACGTCGACCACATCCTGAACGGCACGCTGCTG
CCGGAGATCGCGGGCCACGTGCTCGGCCGGATCGCCGACGGCGCGGCGATCGCGCGCATCGCGGTGCGCGCGGACGAGGC
CGGCGAATTCGCGTACACCGTCGAATGA