Detailed information of component protein


Summary

Component ID T6CP011356
Component protein type TagL
T6SS ID (Type) T6SS00037 experimental (Type i2)
Strain Escherichia coli CFT073
Replicon chromosome
Sequence Protein sequence (551 a.a.); Nucleotide sequence (1653 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) C_RS16085
Coordinate (Strand) 3227152..3228804 (+)
NCBI ID WP_001246526.1
RefSeq NC_004431
Uniprot ID A0A0H2VA37_ECOL6, A0A1L1K0F2_ECOLX
KEGG ID ecc:c3389
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
OmpA PF00691.22 7.5e-17 437..533
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-6 VRNTLK
Transmembrane helix 7-25 QAIVLWGMVLLLVLWSVFI
Outside 26-29 SPSG
Transmembrane helix 30-49 VLRWAGAAAIVLAVAALLIY
Inside 50-316 RRRQAWTEMTGDAGLSSLPPETYRQPVVLVCGGLSAHLSTDSPVRQVSEGLYLHVPDEEQLVAQVERLLTLRPAWASQLAVAYTIMPGIHRDVAVLAGRLRRFAHSMATVRRRAGVNVPWLLWSGLSGSPLPERASSPWFICTGGEVQVATSTETTMPAQWIAQSGVQERSQRLCYLLKAESLMQWLNLNVLTALNGPEAKCPPLAMTVGLVPSLPAVDNNLWQLWITARTGLTPDIADTGTDDALPFPDALLRQLPRQSGFTPLRR
Transmembrane helix 317-339 ACVTMLGVTTVAGIAALCLSATA
Outside 340-550 NRQLLRQVGDDLHRFYAVPVEEFITKARHLSVLKDDATMLDGYYREGEPLRLGLGLYPGERIRQPVLRAIRDWRPPEQKMEVTASLQVQTVRLDSMSLFDVGQARLKDGSTKVLVDALVNIRAKPGWLILVAGYTDATGDEKSNQQLSLRRAEAVRNWMLQTSDIPATCFAVQGLGESQPAATNDTPQGRAVNRRVEISLVPRSDACQDVK


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9923 - -


  Protein sequence: 551 a.a.    

>T6CP011356 NC_004431:3227152-3228804 [Escherichia coli CFT073] [TagL]
VRNTLKQAIVLWGMVLLLVLWSVFISPSGVLRWAGAAAIVLAVAALLIYRRRQAWTEMTGDAGLSSLPPETYRQPVVLVC
GGLSAHLSTDSPVRQVSEGLYLHVPDEEQLVAQVERLLTLRPAWASQLAVAYTIMPGIHRDVAVLAGRLRRFAHSMATVR
RRAGVNVPWLLWSGLSGSPLPERASSPWFICTGGEVQVATSTETTMPAQWIAQSGVQERSQRLCYLLKAESLMQWLNLNV
LTALNGPEAKCPPLAMTVGLVPSLPAVDNNLWQLWITARTGLTPDIADTGTDDALPFPDALLRQLPRQSGFTPLRRACVT
MLGVTTVAGIAALCLSATANRQLLRQVGDDLHRFYAVPVEEFITKARHLSVLKDDATMLDGYYREGEPLRLGLGLYPGER
IRQPVLRAIRDWRPPEQKMEVTASLQVQTVRLDSMSLFDVGQARLKDGSTKVLVDALVNIRAKPGWLILVAGYTDATGDE
KSNQQLSLRRAEAVRNWMLQTSDIPATCFAVQGLGESQPAATNDTPQGRAVNRRVEISLVPRSDACQDVK*

  Nucleotide sequence: 1653 bp    

>T6CP011356 NC_004431:3227152-3228804 [Escherichia coli CFT073] [TagL]
GTGAGGAACACGCTGAAACAGGCCATCGTGCTGTGGGGAATGGTGTTACTGCTGGTGCTGTGGTCAGTGTTTATCAGTCC
GTCTGGCGTGCTGAGATGGGCCGGTGCGGCGGCTATCGTTCTGGCGGTTGCCGCGTTGTTGATTTATCGGCGCAGGCAGG
CGTGGACGGAGATGACCGGCGATGCCGGGTTGTCATCGCTGCCGCCGGAAACCTACCGACAGCCGGTAGTGCTGGTCTGT
GGCGGTCTGTCGGCGCACCTGTCCACTGACAGCCCGGTCCGCCAGGTTTCAGAAGGGCTGTATCTGCATGTTCCTGATGA
AGAACAGCTTGTGGCGCAGGTGGAGCGATTGCTGACCCTTCGCCCGGCGTGGGCATCGCAGCTTGCCGTGGCGTATACCA
TCATGCCCGGCATACACCGGGATGTGGCGGTTCTGGCCGGACGGCTGCGACGGTTCGCCCACAGTATGGCGACGGTGCGT
CGTCGGGCAGGCGTAAACGTCCCCTGGCTTCTCTGGAGCGGGCTGTCCGGCTCGCCGTTGCCGGAAAGAGCGAGTTCACC
GTGGTTTATCTGTACCGGCGGCGAAGTTCAGGTAGCAACATCCACAGAGACCACCATGCCCGCGCAGTGGATTGCACAAT
CCGGCGTACAGGAGCGCAGTCAGCGACTCTGTTACCTGCTGAAAGCTGAAAGCCTGATGCAGTGGCTGAATCTTAATGTG
CTGACGGCACTGAACGGCCCGGAGGCGAAATGTCCACCACTGGCGATGACCGTGGGGCTGGTCCCCTCGTTGCCTGCGGT
GGATAACAACCTGTGGCAGTTGTGGATCACCGCCAGAACCGGCCTGACGCCGGATATCGCGGACACCGGCACAGACGATG
CGCTGCCATTCCCGGATGCCCTGTTACGGCAGTTGCCGCGTCAGTCGGGCTTTACCCCGCTGCGACGAGCCTGCGTGACC
ATGCTGGGCGTCACCACCGTGGCGGGTATCGCCGCGCTGTGCCTGTCAGCCACGGCAAATCGCCAGTTATTACGGCAGGT
CGGTGACGATCTGCACCGGTTTTATGCCGTCCCGGTGGAGGAATTTATCACCAAAGCCCGTCACCTGTCGGTGCTGAAAG
ACGATGCGACCATGCTCGATGGGTATTACCGGGAAGGAGAACCCCTGCGCCTCGGTCTGGGGTTATACCCCGGCGAACGC
ATCCGCCAGCCGGTATTACGCGCCATTCGCGACTGGCGTCCGCCTGAACAAAAAATGGAGGTGACGGCTTCGCTTCAGGT
TCAGACCGTGCGTCTTGACAGTATGTCGCTGTTTGACGTCGGACAGGCCCGCCTGAAAGACGGCTCGACAAAAGTGCTGG
TGGACGCACTGGTGAACATCCGGGCAAAACCGGGCTGGCTGATCCTCGTGGCCGGATATACCGATGCCACCGGCGATGAA
AAAAGCAATCAGCAGTTATCGCTGCGGCGTGCCGAAGCGGTGCGCAACTGGATGCTGCAGACCAGCGACATCCCGGCCAC
CTGTTTTGCCGTACAGGGACTGGGCGAGAGCCAGCCTGCGGCGACCAACGACACGCCACAGGGCCGGGCAGTCAACCGGC
GTGTCGAAATCAGTCTTGTTCCGCGTTCTGACGCCTGTCAGGACGTGAAATAA