Detailed information of component protein


Summary

Component ID T6CP010083
Component protein type TssM
T6SS ID (Type) T6SS00838 experimental (Type i1)
Strain Proteus mirabilis BB2000
Replicon chromosome
Sequence Protein sequence (1183 a.a.); Nucleotide sequence (3549 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) BB2000_RS03920
Coordinate (Strand) 920271..923819 (-)
NCBI ID WP_020945427.1
RefSeq NC_022000
Uniprot ID UPI0003842043
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 3.2e-68 515..827
IcmF-related_N PF14331.8 3e-60 214..463
IcmF_C PF06744.14 9.4e-18 1056..1158
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-25 MKLPVFSISNITSSVKKLFFADKSK
Transmembrane helix 26-48 IASFLLFLLALLPALLIIWIWWW
Outside 49-62 GPTFRYQDSIPFSE
Transmembrane helix 63-85 VTTRWLATVVIVLLVVSWIGLAT
Inside 86-458 WRRVKKLEALKLDVELAVVDPVRQDLDFQKRYLNYWKSQFIRHLNGHTKAVYLRPWYFVLGANQSGKHSLLKNTVNPLDIAPSDNIVNEQNIALNIQCLLTDNAVLFVPNGDLLTQPANQADKPQLYHRLWGDLLNWIKTNRPRQPMNGIVLTVDTLSLLTNSKEQNSQLLADLQMRIEEIRMTFNSRLPLYIVLTKLDLLRGFDSMYQSLDVQQRNEVLGVSFNQKAKSNWKKELNHFWSQWVGQMNSALPEMMLQRAEGNQRSDLFSFVRQIEGLQHSVCTLIDALLINNEQHNICLRGVYLTSALQIGQIDDVFSQTASEQYHLPTAPLTTWPINDSHPYFTTQLFSQVLFSEPNIAAENHYWVKKHRTR
Transmembrane helix 459-481 LLVTTAVSFVGLIAIWNGWSHYY
Outside 482-1182 DKNYRAGENVLNEVKAFRAIENNAQKDTDGSLQLPVLNPLREATLAYGNHRDKNVLFSDMGLYQGQKVGPQVEQVYLQLLTDRFLPAVMSGLLNELNSADKGSEDKLEILRIMRMLEDKSGRNNGMVEDFMADYWSQLFTGQREKQLQLKAHLRYALEHTDWKQEREKGFVSATKAFMPFAGPIKNAQAELSVLSLYQRVYQALRLKANQELSAPLNLQHQIGPSFNTVFTAIDDDKLEIPQFLTRSGLLNYFIRQNDKLVELTLLDAWVLNLTTNTQYSESDRKEIQRQISEQYLSDYTAQWRNAMSNLEIRQFDSIQDEITALEQIISGEQPLRRALQVLRDNTVIPTIDENLPLDEQKTLMAEPSYRLLTRLDREFTPQTEILVSNQGENLQNLNQKLNDLHRYLLGIQNSPVPGKAALKAVSMRLNDNNRDAIFELSQMAKTLPEPLNRWVDELSVQAWNVVQKEAIRYMEVEWNENVVKQYNTYIAGRYPFNPAAKQDVPLSEFERFFKPNGTLDSFYQQNLRLFVENNLVNDSDSQSLIRADVLAQIEIANRIRETFFNAQGNLEAQYAIEPLSLSGNKRRSILNLDGQLIDYAHSRSHVTHLVWPNSMRSNIESKLTLVPLSGDKSPRSISFSGPWAQMRLVDNAKLINIKPNSFDIRFTIDGGDMTYRVIVDESNNPFFGGLFTKFRLPETLY


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9935 - -


  Protein sequence: 1183 a.a.    

>T6CP010083 NC_022000:c923819-920271 [Proteus mirabilis BB2000] [TssM]
MKLPVFSISNITSSVKKLFFADKSKIASFLLFLLALLPALLIIWIWWWGPTFRYQDSIPFSEVTTRWLATVVIVLLVVSW
IGLATWRRVKKLEALKLDVELAVVDPVRQDLDFQKRYLNYWKSQFIRHLNGHTKAVYLRPWYFVLGANQSGKHSLLKNTV
NPLDIAPSDNIVNEQNIALNIQCLLTDNAVLFVPNGDLLTQPANQADKPQLYHRLWGDLLNWIKTNRPRQPMNGIVLTVD
TLSLLTNSKEQNSQLLADLQMRIEEIRMTFNSRLPLYIVLTKLDLLRGFDSMYQSLDVQQRNEVLGVSFNQKAKSNWKKE
LNHFWSQWVGQMNSALPEMMLQRAEGNQRSDLFSFVRQIEGLQHSVCTLIDALLINNEQHNICLRGVYLTSALQIGQIDD
VFSQTASEQYHLPTAPLTTWPINDSHPYFTTQLFSQVLFSEPNIAAENHYWVKKHRTRLLVTTAVSFVGLIAIWNGWSHY
YDKNYRAGENVLNEVKAFRAIENNAQKDTDGSLQLPVLNPLREATLAYGNHRDKNVLFSDMGLYQGQKVGPQVEQVYLQL
LTDRFLPAVMSGLLNELNSADKGSEDKLEILRIMRMLEDKSGRNNGMVEDFMADYWSQLFTGQREKQLQLKAHLRYALEH
TDWKQEREKGFVSATKAFMPFAGPIKNAQAELSVLSLYQRVYQALRLKANQELSAPLNLQHQIGPSFNTVFTAIDDDKLE
IPQFLTRSGLLNYFIRQNDKLVELTLLDAWVLNLTTNTQYSESDRKEIQRQISEQYLSDYTAQWRNAMSNLEIRQFDSIQ
DEITALEQIISGEQPLRRALQVLRDNTVIPTIDENLPLDEQKTLMAEPSYRLLTRLDREFTPQTEILVSNQGENLQNLNQ
KLNDLHRYLLGIQNSPVPGKAALKAVSMRLNDNNRDAIFELSQMAKTLPEPLNRWVDELSVQAWNVVQKEAIRYMEVEWN
ENVVKQYNTYIAGRYPFNPAAKQDVPLSEFERFFKPNGTLDSFYQQNLRLFVENNLVNDSDSQSLIRADVLAQIEIANRI
RETFFNAQGNLEAQYAIEPLSLSGNKRRSILNLDGQLIDYAHSRSHVTHLVWPNSMRSNIESKLTLVPLSGDKSPRSISF
SGPWAQMRLVDNAKLINIKPNSFDIRFTIDGGDMTYRVIVDESNNPFFGGLFTKFRLPETLY*

  Nucleotide sequence: 3549 bp    

>T6CP010083 NC_022000:c923819-920271 [Proteus mirabilis BB2000] [TssM]
ATGAAATTACCGGTTTTCTCCATTTCAAACATTACGAGTTCGGTAAAAAAACTCTTTTTTGCTGATAAATCTAAAATTGC
CTCCTTTTTGCTATTTTTATTGGCATTACTTCCCGCTTTGCTCATTATTTGGATCTGGTGGTGGGGGCCAACATTTCGTT
ATCAAGATTCCATACCGTTTAGCGAGGTCACCACACGTTGGTTAGCAACCGTCGTTATTGTATTGCTTGTTGTGAGTTGG
ATTGGTCTAGCAACATGGCGTCGAGTTAAAAAATTGGAAGCATTAAAACTTGATGTCGAATTAGCTGTAGTTGATCCGGT
AAGACAAGATCTTGATTTTCAAAAACGTTATTTAAACTATTGGAAATCACAATTTATTCGTCACTTAAATGGTCATACTA
AAGCGGTTTATTTACGCCCTTGGTATTTTGTTTTAGGTGCTAACCAAAGTGGAAAGCATAGCTTATTAAAAAATACGGTA
AACCCATTAGATATTGCGCCTAGCGACAATATTGTTAACGAACAAAATATTGCATTAAATATTCAATGTCTATTAACCGA
CAATGCTGTACTTTTTGTCCCTAATGGTGATCTATTAACCCAGCCGGCAAATCAGGCTGATAAACCTCAACTTTATCACC
GTTTGTGGGGCGATTTACTCAATTGGATCAAAACTAACCGCCCAAGACAACCAATGAATGGCATCGTCTTAACTGTCGAT
ACCCTATCGTTATTAACCAATAGTAAGGAGCAAAATAGTCAGCTACTTGCTGATTTACAAATGCGTATTGAAGAAATACG
CATGACATTTAATAGTCGCTTGCCTTTATATATCGTCTTAACCAAGCTAGATCTATTACGTGGTTTTGACTCAATGTATC
AATCATTAGATGTTCAACAACGTAATGAAGTATTAGGTGTTTCTTTCAACCAGAAAGCAAAAAGTAATTGGAAAAAGGAA
TTAAATCATTTTTGGTCACAATGGGTAGGCCAAATGAACAGCGCATTACCAGAAATGATGCTACAAAGAGCAGAAGGTAA
CCAGCGTAGTGATCTATTTAGTTTCGTGCGCCAAATTGAAGGGTTACAACATTCTGTATGCACATTAATTGATGCATTGC
TCATCAATAATGAGCAACATAATATCTGTTTAAGAGGGGTTTATTTAACTTCTGCATTGCAAATCGGTCAAATCGATGAT
GTGTTTAGCCAAACAGCGTCCGAACAATATCATTTACCAACAGCACCTCTTACTACATGGCCAATTAATGATAGCCACCC
TTATTTTACTACCCAATTATTTAGTCAAGTGCTATTTAGTGAGCCTAATATTGCAGCAGAAAACCATTATTGGGTTAAAA
AACATCGGACTCGCCTATTAGTCACCACTGCTGTTAGCTTTGTCGGCTTAATCGCAATTTGGAATGGTTGGAGCCACTAT
TACGACAAAAACTATCGTGCTGGAGAAAACGTTCTTAATGAGGTAAAAGCATTCCGTGCTATTGAGAACAATGCTCAGAA
AGATACTGATGGTAGCCTACAATTACCGGTGCTCAATCCATTACGTGAAGCAACCTTAGCTTATGGTAATCATCGTGATA
AAAATGTGCTCTTTTCTGATATGGGTCTTTACCAAGGTCAAAAAGTAGGCCCACAAGTTGAACAAGTCTATTTACAACTA
CTCACCGATCGCTTTTTACCTGCGGTTATGTCTGGGTTGTTAAATGAACTTAACAGTGCCGATAAAGGAAGTGAAGATAA
GTTAGAGATATTGCGTATTATGCGCATGTTAGAAGATAAAAGTGGCCGTAATAATGGCATGGTAGAAGATTTTATGGCTG
ATTATTGGAGCCAACTGTTCACTGGTCAACGTGAAAAACAACTGCAACTAAAAGCCCATTTGCGCTATGCCCTTGAGCAC
ACAGATTGGAAACAAGAGCGTGAAAAAGGGTTTGTTTCAGCCACTAAAGCCTTTATGCCTTTTGCTGGACCTATAAAAAA
TGCACAAGCAGAGTTAAGTGTATTGTCACTTTATCAGCGTGTATATCAAGCCTTACGCTTAAAGGCTAATCAAGAGCTTT
CAGCGCCTTTAAATTTACAACATCAAATTGGCCCAAGTTTTAATACGGTCTTTACGGCTATTGATGATGATAAATTAGAA
ATTCCACAATTCTTAACGCGCTCAGGGTTATTAAACTATTTTATCCGCCAAAATGATAAATTGGTCGAGCTAACATTACT
TGATGCTTGGGTTCTTAATCTAACCACCAACACACAATATAGTGAAAGTGATCGTAAAGAAATTCAGCGTCAAATCAGTG
AACAATATCTTAGTGACTATACGGCTCAATGGCGTAATGCCATGAGCAATTTAGAAATTCGTCAATTTGATTCAATACAA
GATGAAATTACCGCTCTTGAGCAAATTATTAGTGGTGAACAACCATTACGCCGAGCATTACAAGTTCTACGTGATAACAC
GGTTATTCCAACTATTGATGAAAATTTACCACTTGATGAACAAAAAACACTGATGGCTGAGCCATCTTACCGTTTATTAA
CCCGCTTAGATCGCGAATTTACTCCTCAAACTGAGATATTAGTCAGTAACCAAGGGGAAAATTTACAGAATCTGAATCAA
AAACTAAATGACTTACATCGTTACCTATTGGGGATCCAAAACTCTCCAGTGCCGGGGAAAGCGGCGCTTAAAGCAGTTTC
GATGCGCTTAAACGATAATAATCGCGACGCTATTTTTGAGCTATCACAAATGGCGAAAACATTACCAGAGCCGCTTAACC
GCTGGGTCGATGAGTTATCAGTGCAAGCATGGAATGTGGTCCAAAAAGAAGCTATTCGTTATATGGAAGTAGAATGGAAT
GAAAATGTTGTCAAACAATACAATACTTATATTGCCGGTCGTTATCCATTTAACCCAGCAGCTAAACAAGATGTTCCTTT
AAGTGAATTTGAACGTTTCTTCAAACCAAATGGAACATTAGATAGCTTCTATCAACAAAATCTGCGTTTATTCGTTGAGA
ATAACTTAGTTAACGATAGTGATAGCCAATCATTGATCCGCGCTGATGTATTAGCACAAATTGAAATAGCCAATCGTATT
AGAGAAACCTTCTTTAATGCCCAAGGTAATTTAGAAGCACAATATGCTATTGAGCCACTGTCATTAAGTGGTAATAAGCG
TCGTAGCATCTTAAATCTTGATGGACAATTGATTGATTACGCTCATAGTCGCAGCCATGTGACACACTTGGTATGGCCAA
ACTCAATGCGTTCCAATATTGAAAGTAAACTGACTTTAGTGCCTCTTTCCGGTGATAAATCGCCACGTTCAATCAGTTTC
TCTGGGCCATGGGCACAAATGCGATTAGTTGATAATGCAAAACTCATTAATATCAAACCTAACTCATTCGATATTCGCTT
CACAATCGACGGTGGTGATATGACTTATCGAGTTATAGTTGATGAATCTAATAATCCTTTCTTCGGTGGATTATTCACAA
AATTCCGTTTACCTGAAACGCTTTATTAA