Detailed information of component protein


Summary

Component ID T6CP009457
Component protein type TssA
T6SS ID (Type) T6SS00344 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
Replicon chromosome
Sequence Protein sequence (533 a.a.); Nucleotide sequence (1599 bp)
Reference
experimental Experimental investigation has been performed on this T6SS

External database links

Locus tag (Gene) KP1_RS11300
Coordinate (Strand) 2321926..2323524 (+)
NCBI ID WP_015874732.1
RefSeq NC_012731
Uniprot ID A0A1F2LXG3_9ENTR, A0A652Q190_9ENTR, A0A6I4LK35_9ENTR, A0A0J4XRE9_KLEPN, A0A3F3BQV4_KLEPN
KEGG ID -
PDB ID -

Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
T6SS_VasJ PF16989.7 5.1e-67 230..488
ImpA_N PF06812.14 3.9e-23 33..137

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-532 MSILQNLVAASQLDESVLRQQARSRQAQWQSWLSPISDSQPTGSDPGYDDDFQRIREEVNKISGVDTVLICQLAGQLLATTKDIRIVTYYCWARLHQDGEAGLADGLELLAGLLQRYGMQLYPQRDRSRKAAIEWLAGTRILDSLSLFPEVVREDARRTVGALLLIDDCLTTEPETSRPDLQALWGALESRLIKGGGVDAVVPQNVGNRGLAQTASRMAEYEAPVLSNITSGQDLLAQARTLTAYLRVQPDGWLAAHRLMKSLRHDTLTIIPAPDAEGKTRIEPPRADQRAMLKRLYLQQSWSEILEQADSTFSRGANHLWLDLQWYIHQALVRSGQDVLADIIIADLKGLLRRLTGLETLAFNDGTPFADEVTLNWINQSVLDDMSVWQDEPVSAASGADNDILALEPEALEKADTDGLDAALHWIQTRPGTESTKEKWLLRLLMARVAEQKGKNDLALYLLRELDDAAGSITLTQWIPALLFEIKSRRLRLLRMKATRSESEKLRLQPEMDQLLAGLIALDPASSAVLCG



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9766 - -



  Protein sequence: 533 a.a.    

>T6CP009457 NC_012731:2321926-2323524 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssA]
MSILQNLVAASQLDESVLRQQARSRQAQWQSWLSPISDSQPTGSDPGYDDDFQRIREEVNKISGVDTVLICQLAGQLLAT
TKDIRIVTYYCWARLHQDGEAGLADGLELLAGLLQRYGMQLYPQRDRSRKAAIEWLAGTRILDSLSLFPEVVREDARRTV
GALLLIDDCLTTEPETSRPDLQALWGALESRLIKGGGVDAVVPQNVGNRGLAQTASRMAEYEAPVLSNITSGQDLLAQAR
TLTAYLRVQPDGWLAAHRLMKSLRHDTLTIIPAPDAEGKTRIEPPRADQRAMLKRLYLQQSWSEILEQADSTFSRGANHL
WLDLQWYIHQALVRSGQDVLADIIIADLKGLLRRLTGLETLAFNDGTPFADEVTLNWINQSVLDDMSVWQDEPVSAASGA
DNDILALEPEALEKADTDGLDAALHWIQTRPGTESTKEKWLLRLLMARVAEQKGKNDLALYLLRELDDAAGSITLTQWIP
ALLFEIKSRRLRLLRMKATRSESEKLRLQPEMDQLLAGLIALDPASSAVLCG*

  Nucleotide sequence: 1599 bp    

>T6CP009457 NC_012731:2321926-2323524 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssA]
ATGAGCATTTTACAAAATTTGGTTGCCGCCAGTCAGTTGGATGAAAGCGTACTGCGCCAGCAGGCCCGGTCACGTCAGGC
GCAGTGGCAGTCCTGGCTTTCGCCAATCAGTGATAGCCAGCCCACCGGGAGCGATCCGGGCTATGACGATGATTTTCAGC
GTATCCGCGAGGAGGTCAATAAGATCTCCGGTGTCGATACCGTACTGATTTGCCAGTTGGCTGGACAGTTACTGGCAACA
ACAAAAGATATCCGGATTGTTACCTATTACTGCTGGGCCCGTTTGCACCAGGACGGGGAAGCTGGCTTGGCCGATGGGCT
GGAGCTGCTGGCAGGCTTGCTGCAACGATATGGTATGCAGCTTTATCCGCAGCGCGACCGTAGCCGCAAAGCAGCCATCG
AGTGGCTGGCGGGTACTCGTATCTTAGACAGTCTTTCACTTTTTCCAGAAGTTGTGCGGGAGGACGCAAGGCGTACCGTC
GGCGCGCTGCTTCTCATTGATGATTGTCTGACGACAGAACCAGAAACATCACGGCCAGATCTGCAAGCACTCTGGGGTGC
ACTGGAGTCTCGTTTGATAAAGGGCGGGGGAGTCGATGCGGTGGTGCCGCAGAACGTCGGAAACCGGGGGCTGGCTCAAA
CCGCTTCACGCATGGCTGAATACGAAGCGCCGGTTCTCAGTAACATCACCTCCGGTCAGGATCTGCTGGCCCAGGCGCGA
ACCCTGACAGCATATCTGCGTGTTCAACCCGATGGCTGGCTTGCCGCACATCGGCTAATGAAAAGCCTTCGTCATGACAC
CTTGACAATCATCCCTGCGCCTGATGCTGAAGGAAAAACACGTATCGAGCCTCCCAGAGCAGATCAGCGTGCCATGCTCA
AGCGGCTGTACCTGCAACAGAGCTGGTCGGAGATACTGGAACAGGCGGACAGTACCTTCTCACGTGGCGCTAACCACCTC
TGGCTTGACCTGCAATGGTATATCCATCAGGCGCTGGTGAGGTCGGGTCAGGATGTGCTGGCCGATATTATAATTGCCGA
TCTGAAAGGATTGCTGCGCCGTCTCACCGGGCTTGAAACATTAGCTTTTAACGACGGCACACCCTTTGCCGATGAGGTCA
CGCTGAACTGGATAAATCAGAGTGTCCTCGACGATATGTCCGTCTGGCAGGATGAGCCAGTATCGGCTGCCAGCGGCGCT
GATAACGACATTCTGGCCCTTGAACCTGAAGCGCTCGAGAAGGCTGACACTGACGGTCTCGATGCTGCACTCCACTGGAT
TCAGACGCGCCCGGGCACTGAATCCACTAAAGAAAAATGGCTGTTGCGCCTGCTTATGGCCCGCGTGGCCGAACAAAAGG
GGAAGAATGACCTCGCGCTCTATCTTCTGCGAGAACTCGACGATGCGGCGGGATCAATCACCCTCACGCAGTGGATCCCA
GCCCTGTTGTTCGAGATTAAATCGCGACGGCTCAGGCTACTGCGCATGAAAGCCACGCGCAGCGAGAGTGAAAAGTTACG
ATTGCAACCGGAGATGGATCAATTGCTGGCAGGTCTGATTGCGCTCGATCCAGCCAGTAGCGCGGTGCTTTGCGGCTAA