Detailed information of component protein
Summary
| Component ID | T6CP008983 |
| Component protein type | TssA |
| T6SS ID (Type) | T6SS00549  (Type Unknown) |
| Strain | Klebsiella pneumoniae subsp. pneumoniae HS11286 |
| Replicon | chromosome |
| Sequence | Protein sequence (472 a.a.); Nucleotide sequence (1416 bp) |
| Reference | - |
Bioinformatics investigation has been performed on this T6SSExternal database links
| Locus tag (Gene) | KPHS_32450 |
| Coordinate (Strand) | 3235063..3236478 (-) |
| NCBI ID | YP_005227545.1 |
| RefSeq | NC_016845 |
| Uniprot ID | - |
| KEGG ID | - |
| PDB ID | - |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| VasL | PF12486.10 | 1.1e-52 | 303..447 |
| ImpA_N | PF06812.14 | 5.7e-21 | 8..112 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Inside | 1-246 | MMTTHHDRHYKAGGDPRTLADFMALRAEMNKLSHPARPDINWPYAEQLARGLLEHHGADLQTVAWYTLARARLGGVAGINEGLTLMESLLVRQGKNLWPQALPARTEIFRTLSKRLRQVIRTLNLTPEDVESLEQAERSLQSFDAVLQRLEIAPENQLSDLRALLHSTATRFESLDPAPALPTAPPVAVSDAELPGTLVSEEDAAKVEPVPDLKRRPKAEPLAPPSPAKRPAPVAASTPAAAPRWK |
| Transmembrane helix | 247-269 | PFIAGMVTMLAVTGIAVGGWLAL |
| Outside | 270-471 | RQSDLPPISVTQNAGPIPGLPATTPPGPVDLPQTQRQLGELARLAPDWAVSYGDQLVHQALIRWPDQAQPLAQQWRQQLSAGALPAENLTGWSEGMQQLQRLADQLNALDEQKGKYLTVSELKTAVFAITQSFNRAVPLEEQLRQLAALPVDQPWPAARGSLAELHLQQLIVEYALLKRKQPASPTAALPATGEPSVSEAVK |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9867 | - | - |
Protein sequence: 472 a.a.
>T6CP008983 NC_016845:c3236478-3235063 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssA]
MMTTHHDRHYKAGGDPRTLADFMALRAEMNKLSHPARPDINWPYAEQLARGLLEHHGADLQTVAWYTLARARLGGVAGIN
EGLTLMESLLVRQGKNLWPQALPARTEIFRTLSKRLRQVIRTLNLTPEDVESLEQAERSLQSFDAVLQRLEIAPENQLSD
LRALLHSTATRFESLDPAPALPTAPPVAVSDAELPGTLVSEEDAAKVEPVPDLKRRPKAEPLAPPSPAKRPAPVAASTPA
AAPRWKPFIAGMVTMLAVTGIAVGGWLALRQSDLPPISVTQNAGPIPGLPATTPPGPVDLPQTQRQLGELARLAPDWAVS
YGDQLVHQALIRWPDQAQPLAQQWRQQLSAGALPAENLTGWSEGMQQLQRLADQLNALDEQKGKYLTVSELKTAVFAITQ
SFNRAVPLEEQLRQLAALPVDQPWPAARGSLAELHLQQLIVEYALLKRKQPASPTAALPATGEPSVSEAVK*
MMTTHHDRHYKAGGDPRTLADFMALRAEMNKLSHPARPDINWPYAEQLARGLLEHHGADLQTVAWYTLARARLGGVAGIN
EGLTLMESLLVRQGKNLWPQALPARTEIFRTLSKRLRQVIRTLNLTPEDVESLEQAERSLQSFDAVLQRLEIAPENQLSD
LRALLHSTATRFESLDPAPALPTAPPVAVSDAELPGTLVSEEDAAKVEPVPDLKRRPKAEPLAPPSPAKRPAPVAASTPA
AAPRWKPFIAGMVTMLAVTGIAVGGWLALRQSDLPPISVTQNAGPIPGLPATTPPGPVDLPQTQRQLGELARLAPDWAVS
YGDQLVHQALIRWPDQAQPLAQQWRQQLSAGALPAENLTGWSEGMQQLQRLADQLNALDEQKGKYLTVSELKTAVFAITQ
SFNRAVPLEEQLRQLAALPVDQPWPAARGSLAELHLQQLIVEYALLKRKQPASPTAALPATGEPSVSEAVK*
Nucleotide sequence: 1416 bp
>T6CP008983 NC_016845:c3236478-3235063 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssA]
ATGATGACAACACACCACGACCGTCACTATAAAGCCGGTGGCGACCCGCGCACGCTGGCTGATTTTATGGCCCTGCGTGC
GGAAATGAACAAGCTCAGCCACCCGGCGCGGCCGGATATTAACTGGCCGTATGCCGAGCAGCTTGCCCGCGGGCTGTTGG
AGCATCACGGCGCGGACCTGCAGACTGTCGCCTGGTATACCCTGGCCCGCGCCCGGCTGGGCGGGGTGGCAGGGATCAAT
GAGGGGCTGACGCTGATGGAGTCGCTGCTGGTTCGTCAGGGGAAAAACCTGTGGCCACAGGCGCTCCCGGCCCGGACAGA
GATCTTCCGCACCCTGAGCAAGCGGCTGCGGCAGGTGATCCGTACCCTGAATCTTACCCCAGAGGATGTTGAGTCGCTTG
AGCAGGCTGAACGTTCGCTGCAAAGCTTCGACGCAGTGCTCCAGCGCCTTGAGATCGCTCCTGAAAACCAGCTGAGCGAC
CTGCGGGCGCTACTGCACAGCACGGCAACTCGCTTCGAGAGCCTCGACCCTGCGCCAGCGCTTCCCACCGCGCCGCCGGT
GGCGGTGTCTGACGCGGAACTTCCCGGCACTCTGGTCAGCGAAGAGGATGCGGCGAAGGTTGAGCCAGTGCCAGACCTAA
AACGTAGACCAAAGGCTGAGCCGCTGGCTCCGCCTTCACCTGCAAAGCGGCCCGCGCCGGTGGCGGCGTCTACTCCGGCA
GCCGCGCCGCGCTGGAAGCCGTTTATCGCCGGGATGGTTACCATGCTGGCGGTAACGGGTATCGCCGTCGGCGGATGGCT
GGCGCTGCGTCAGTCCGACTTGCCGCCCATTTCAGTCACCCAAAATGCCGGACCGATACCGGGCCTGCCGGCGACAACGC
CCCCGGGGCCGGTTGATCTGCCACAGACGCAGCGCCAGCTTGGCGAGCTTGCCCGCCTGGCGCCGGACTGGGCGGTCAGC
TACGGCGACCAGCTGGTCCACCAGGCCCTGATCCGCTGGCCGGATCAGGCGCAACCGCTGGCGCAGCAGTGGCGGCAGCA
GCTGAGTGCTGGCGCATTGCCCGCGGAAAACCTTACCGGCTGGTCGGAGGGCATGCAGCAGCTGCAGCGGCTCGCCGACC
AGCTCAATGCCCTCGACGAGCAGAAGGGGAAGTACCTGACGGTGAGCGAACTGAAAACCGCAGTATTTGCCATCACACAG
TCGTTTAACCGCGCTGTTCCGCTGGAGGAGCAGCTGCGCCAGCTGGCCGCGCTTCCCGTTGATCAACCCTGGCCAGCCGC
GCGGGGAAGCCTCGCGGAGCTGCATCTGCAACAGCTGATAGTGGAGTATGCCCTGCTGAAGCGAAAACAGCCGGCGTCGC
CGACCGCTGCGCTCCCCGCAACCGGTGAGCCCTCGGTGAGTGAGGCGGTGAAATAA
ATGATGACAACACACCACGACCGTCACTATAAAGCCGGTGGCGACCCGCGCACGCTGGCTGATTTTATGGCCCTGCGTGC
GGAAATGAACAAGCTCAGCCACCCGGCGCGGCCGGATATTAACTGGCCGTATGCCGAGCAGCTTGCCCGCGGGCTGTTGG
AGCATCACGGCGCGGACCTGCAGACTGTCGCCTGGTATACCCTGGCCCGCGCCCGGCTGGGCGGGGTGGCAGGGATCAAT
GAGGGGCTGACGCTGATGGAGTCGCTGCTGGTTCGTCAGGGGAAAAACCTGTGGCCACAGGCGCTCCCGGCCCGGACAGA
GATCTTCCGCACCCTGAGCAAGCGGCTGCGGCAGGTGATCCGTACCCTGAATCTTACCCCAGAGGATGTTGAGTCGCTTG
AGCAGGCTGAACGTTCGCTGCAAAGCTTCGACGCAGTGCTCCAGCGCCTTGAGATCGCTCCTGAAAACCAGCTGAGCGAC
CTGCGGGCGCTACTGCACAGCACGGCAACTCGCTTCGAGAGCCTCGACCCTGCGCCAGCGCTTCCCACCGCGCCGCCGGT
GGCGGTGTCTGACGCGGAACTTCCCGGCACTCTGGTCAGCGAAGAGGATGCGGCGAAGGTTGAGCCAGTGCCAGACCTAA
AACGTAGACCAAAGGCTGAGCCGCTGGCTCCGCCTTCACCTGCAAAGCGGCCCGCGCCGGTGGCGGCGTCTACTCCGGCA
GCCGCGCCGCGCTGGAAGCCGTTTATCGCCGGGATGGTTACCATGCTGGCGGTAACGGGTATCGCCGTCGGCGGATGGCT
GGCGCTGCGTCAGTCCGACTTGCCGCCCATTTCAGTCACCCAAAATGCCGGACCGATACCGGGCCTGCCGGCGACAACGC
CCCCGGGGCCGGTTGATCTGCCACAGACGCAGCGCCAGCTTGGCGAGCTTGCCCGCCTGGCGCCGGACTGGGCGGTCAGC
TACGGCGACCAGCTGGTCCACCAGGCCCTGATCCGCTGGCCGGATCAGGCGCAACCGCTGGCGCAGCAGTGGCGGCAGCA
GCTGAGTGCTGGCGCATTGCCCGCGGAAAACCTTACCGGCTGGTCGGAGGGCATGCAGCAGCTGCAGCGGCTCGCCGACC
AGCTCAATGCCCTCGACGAGCAGAAGGGGAAGTACCTGACGGTGAGCGAACTGAAAACCGCAGTATTTGCCATCACACAG
TCGTTTAACCGCGCTGTTCCGCTGGAGGAGCAGCTGCGCCAGCTGGCCGCGCTTCCCGTTGATCAACCCTGGCCAGCCGC
GCGGGGAAGCCTCGCGGAGCTGCATCTGCAACAGCTGATAGTGGAGTATGCCCTGCTGAAGCGAAAACAGCCGGCGTCGC
CGACCGCTGCGCTCCCCGCAACCGGTGAGCCCTCGGTGAGTGAGGCGGTGAAATAA