Detailed information of component protein


Summary

Component ID T6CP008791
Component protein type TssA
T6SS ID (Type) T6SS00345 experimental (Type Unknown)
Strain Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
Replicon chromosome
Sequence Protein sequence (472 a.a.); Nucleotide sequence (1416 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KP1_RS15690
Coordinate (Strand) 3190436..3191851 (-)
NCBI ID WP_004200294.1
RefSeq NC_012731
Uniprot ID A0A0H3GRI9_KLEPH, A0A652PZA0_9ENTR, A0A2U0M0W9_KLEPN, A0A3F3BWI2_KLEPN
KEGG ID kpm:KPHS_32450
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
VasL PF12486.10 1.1e-52 303..447
ImpA_N PF06812.14 5.7e-21 8..112
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-246 MMTTHHDRHYKAGGDPRTLADFMALRAEMNKLSHPARPDINWPYAEQLARGLLEHHGADLQTVAWYTLARARLGGVAGINEGLTLMESLLVRQGKNLWPQALPARTEIFRTLSKRLRQVIRTLNLTPEDVESLEQAERSLQSFDAVLQRLEIAPENQLSDLRALLHSTATRFESLDPAPALPTAPPVAVSDAELPGTLVSEEDAAKVEPVPDLKRRPKAEPLAPPSPAKRPAPVAASTPAAAPRWK
Transmembrane helix 247-269 PFIAGMVTMLAVTGIAVGGWLAL
Outside 270-471 RQSDLPPISVTQNAGPIPGLPATTPPGPVDLPQTQRQLGELARLAPDWAVSYGDQLVHQALIRWPDQAQPLAQQWRQQLSAGALPAENLTGWSEGMQQLQRLADQLNALDEQKGKYLTVSELKTAVFAITQSFNRAVPLEEQLRQLAALPVDQPWPAARGSLAELHLQQLIVEYALLKRKQPASPTAALPATGEPSVSEAVK


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9867 - -


  Protein sequence: 472 a.a.    

>T6CP008791 NC_012731:c3191851-3190436 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssA]
MMTTHHDRHYKAGGDPRTLADFMALRAEMNKLSHPARPDINWPYAEQLARGLLEHHGADLQTVAWYTLARARLGGVAGIN
EGLTLMESLLVRQGKNLWPQALPARTEIFRTLSKRLRQVIRTLNLTPEDVESLEQAERSLQSFDAVLQRLEIAPENQLSD
LRALLHSTATRFESLDPAPALPTAPPVAVSDAELPGTLVSEEDAAKVEPVPDLKRRPKAEPLAPPSPAKRPAPVAASTPA
AAPRWKPFIAGMVTMLAVTGIAVGGWLALRQSDLPPISVTQNAGPIPGLPATTPPGPVDLPQTQRQLGELARLAPDWAVS
YGDQLVHQALIRWPDQAQPLAQQWRQQLSAGALPAENLTGWSEGMQQLQRLADQLNALDEQKGKYLTVSELKTAVFAITQ
SFNRAVPLEEQLRQLAALPVDQPWPAARGSLAELHLQQLIVEYALLKRKQPASPTAALPATGEPSVSEAVK*

  Nucleotide sequence: 1416 bp    

>T6CP008791 NC_012731:c3191851-3190436 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] [TssA]
ATGATGACAACACACCACGACCGTCACTATAAAGCCGGTGGCGACCCGCGCACGCTGGCTGATTTTATGGCCCTGCGTGC
GGAAATGAACAAGCTCAGCCACCCGGCGCGGCCGGATATTAACTGGCCGTATGCCGAGCAGCTTGCCCGCGGGCTGTTGG
AGCATCACGGCGCGGACCTGCAGACTGTCGCCTGGTATACCCTGGCCCGCGCCCGGCTGGGCGGGGTGGCAGGGATCAAT
GAGGGGCTGACGCTGATGGAGTCGCTGCTGGTTCGTCAGGGGAAAAACCTGTGGCCACAGGCGCTCCCGGCCCGGACAGA
GATCTTCCGCACCCTGAGCAAGCGGCTGCGGCAGGTGATCCGTACCCTGAATCTTACCCCAGAGGATGTTGAGTCGCTTG
AGCAGGCTGAACGTTCGCTGCAAAGCTTCGACGCAGTACTCCAGCGCCTTGAGATCGCTCCTGAAAACCAGCTGAGCGAC
CTGCGGGCGCTACTGCACAGCACGGCAACTCGCTTCGAGAGCCTCGACCCTGCGCCAGCGCTTCCCACCGCGCCGCCGGT
GGCGGTGTCTGACGCGGAACTTCCCGGCACTCTGGTCAGCGAAGAGGATGCGGCGAAGGTTGAGCCAGTGCCAGACCTAA
AACGTAGACCAAAGGCTGAGCCGCTGGCTCCGCCTTCACCTGCAAAGCGGCCCGCGCCGGTGGCGGCGTCTACTCCCGCA
GCCGCGCCGCGCTGGAAGCCGTTTATCGCCGGGATGGTTACCATGCTGGCGGTAACGGGTATCGCCGTCGGCGGATGGCT
GGCGCTGCGTCAGTCCGACTTGCCGCCCATTTCGGTCACCCAAAATGCCGGACCGATACCGGGCCTGCCGGCGACAACGC
CCCCGGGGCCGGTTGATCTGCCACAGACGCAGCGCCAGCTTGGCGAGCTTGCCCGCCTGGCGCCGGACTGGGCGGTCAGC
TACGGCGACCAGCTGGTCCACCAGGCCCTGATCCGCTGGCCGGATCAGGCGCAACCGCTGGCGCAGCAGTGGCGGCAGCA
GCTGAGTGCTGGCGCATTGCCCGCGGAAAACCTTACCGGCTGGTCGGAGGGCATGCAGCAACTGCAGCGGCTCGCCGACC
AGCTCAATGCCCTCGACGAGCAGAAGGGGAAGTACCTGACGGTGAGCGAACTGAAAACCGCAGTATTTGCCATCACGCAG
TCGTTTAACCGCGCTGTTCCGCTGGAGGAGCAGCTGCGCCAGCTGGCCGCGCTTCCCGTTGATCAACCCTGGCCAGCCGC
GCGGGGAAGCCTCGCGGAGCTGCATCTGCAACAGCTGATAGTGGAGTATGCCCTGCTGAAGCGAAAACAGCCGGCGTCGC
CGACCGCTGCGCTCCCCGCAACCGGTGAGCCCTCGGTGAGTGAGGCGGTGAAATAA