SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP008694
Component protein type	TssD
T6SS ID (Type)	T6SS00272 (Type i1)
Strain	Proteus mirabilis HI4320
Replicon	chromosome
Sequence	Protein sequence (173 a.a.); Nucleotide sequence (519 bp)
Reference	[1] Wenren LM, Sullivan NL, Cardarelli L, et al. Two independent pathways for self-recognition in Proteus mirabilis are linked by type VI-dependent export. mBio. 2013 Jul 23;4(4). pii: e00374-13. doi: 10.1128/mBio.00374-13. PMID: 23882014 [2] Alteri CJ, Himpsl SD, Pickens SR, et al. Multicellular bacteria deploy the type VI secretion system to preemptively strike neighboring cells. PLoS Pathog. 2013;9(9):e1003608. doi: 10.1371/journal.ppat.1003608. Epub 2013 Sep 5. PMID: 24039579

Experimental investigation has been performed on this T6SS

External database links

Locus tag (Gene)	PMI_RS03690
Coordinate (Strand)	831710..832228 (+)
NCBI ID	WP_012367724.1
RefSeq	NC_010554
Uniprot ID	B4EVA3_PROMH
KEGG ID	pmr:PMI0750
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
T6SS_HCP	PF05638.14	3.9e-35	7..155

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-172	MPTPCYISIEGKNQGNITAGAFTADSVGNIYVQGHEDQMLVQEFSHVVTVPTDPQSGQPSGQRAHKPFRFTVALNKAVPLLYNALASGEMLPKVELKWYRTSVEGKQEHFFTTTLTDATIVNIDCQMPHCQDPAKADFTQLIEVSLSYRKIDWEHTVAGTSGADDWRAPLEA

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9745	-	-

Protein sequence: 173 a.a.

						>T6CP008694 NC_010554:831710-832228 [Proteus mirabilis HI4320] [TssD]
MPTPCYISIEGKNQGNITAGAFTADSVGNIYVQGHEDQMLVQEFSHVVTVPTDPQSGQPSGQRAHKPFRFTVALNKAVPL
LYNALASGEMLPKVELKWYRTSVEGKQEHFFTTTLTDATIVNIDCQMPHCQDPAKADFTQLIEVSLSYRKIDWEHTVAGT
SGADDWRAPLEA*					

Nucleotide sequence: 519 bp

						>T6CP008694 NC_010554:831710-832228 [Proteus mirabilis HI4320] [TssD]
ATGCCAACTCCTTGCTATATTTCCATTGAAGGAAAAAATCAGGGCAACATCACTGCAGGCGCGTTTACTGCAGATTCTGT
CGGCAACATTTATGTACAAGGTCATGAAGACCAAATGTTGGTACAAGAATTTTCTCACGTAGTGACGGTTCCGACTGATC
CGCAATCAGGCCAACCTTCTGGCCAACGTGCGCATAAACCGTTTCGTTTTACCGTGGCATTAAACAAAGCCGTTCCTCTG
CTGTATAACGCATTGGCTTCCGGCGAAATGCTGCCAAAAGTTGAGTTAAAATGGTATCGCACGTCTGTTGAAGGTAAACA
AGAGCACTTCTTTACCACCACACTGACTGACGCGACGATCGTGAACATCGATTGCCAAATGCCTCATTGCCAAGATCCGG
CTAAAGCCGACTTCACGCAACTTATCGAAGTCTCCCTCTCTTACCGCAAAATTGACTGGGAGCACACTGTTGCTGGAACG
TCTGGTGCGGATGACTGGCGTGCGCCTCTCGAAGCGTAA					