SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP008529
Component protein type	TssA
T6SS ID (Type)	T6SS00155 (Type i1)
Strain	Escherichia coli APEC O1
Replicon	chromosome
Sequence	Protein sequence (481 a.a.); Nucleotide sequence (1443 bp)
Reference	[1] Boyer F, Fichant G, Berthod J, et al. Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources? BMC Genomics. 2009 Mar 12;10:104. doi: 10.1186/1471-2164-10-104. PMID: 19284603

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	APECO1_RS01160
Coordinate (Strand)	248820..250262 (-)
NCBI ID	WP_001331530.1
RefSeq	NC_008563
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
T6SS_VasJ	PF16989.7	1.9e-70	232..476
ImpA_N	PF06812.14	2.7e-05	32..112

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
		-	-

Protein sequence: 481 a.a.

						>T6CP008529 NC_008563:c250262-248820 [Escherichia coli APEC O1] [TssA]
MAMDLRNPDVWLAHLLENLPEDKLSAALDDGNADWEFVDSEIVKLGSLAHSQLDIPELQRRGLMLLASETKDFRLLAHLL
RTLQHAGDILLASRMLAQYTEHYWTCAAPQNMAHKKRFAAQVIKRFESAVQDFAGNAATIQRDALLGELAKLAQCWQAHN
ASELAKATDDLFSLFQRAFRDVAPEMTSSARSAAIAPQATTGYVPDMSPHTVAAQPPVAATPIPQVTVENHDDKAWRDTL
LKVAAILCERQPESPQGYRLRRHALWQTITSTPQAESDGRTPLAAFPVDMMDDYLARLNNADMALWQQVEKSLLLAPYWL
DGHYLSAQTALRLGYKQVADAIRDEVTDFLARLPALINLLFNDRTPFVSEQTKQWLASSGSVNQTVPVVQTDEELQAAKA
CFDENGLEAALRYLENLPEGDPRHQFHRQFFGAQLLEEAGMVQLAQQQYRMLFRTGLHMMLSEWEPSLLKALEQKLTAEQ
*					

Nucleotide sequence: 1443 bp

						>T6CP008529 NC_008563:c250262-248820 [Escherichia coli APEC O1] [TssA]
ATGGCAATGGACTTACGTAATCCCGATGTATGGCTTGCACACCTGCTGGAAAACCTGCCAGAAGATAAGCTGTCCGCCGC
GCTTGATGATGGCAATGCAGACTGGGAGTTTGTCGACAGCGAAATCGTCAAGCTCGGTTCACTGGCGCACAGCCAGCTTG
ATATCCCGGAACTTCAGCGCCGGGGCCTGATGCTTCTGGCCTCAGAAACCAAAGATTTTCGCCTGCTGGCCCACTTGCTG
CGTACCCTGCAACATGCCGGTGATATTCTGCTGGCCTCCAGGATGCTGGCACAATATACAGAGCACTACTGGACATGCGC
CGCACCGCAGAACATGGCCCACAAAAAACGCTTTGCCGCCCAGGTGATAAAACGCTTTGAGTCTGCCGTTCAGGACTTTG
CCGGGAATGCTGCGACAATACAGCGCGATGCTTTGCTGGGAGAGCTGGCAAAACTGGCACAGTGCTGGCAGGCGCACAAC
GCGTCTGAGCTGGCAAAGGCGACAGACGATTTATTTTCCCTGTTTCAGCGCGCGTTTCGTGATGTAGCGCCTGAAATGAC
ATCATCTGCACGAAGCGCCGCCATTGCGCCGCAGGCCACGACCGGATATGTACCGGATATGTCACCGCACACGGTTGCCG
CTCAGCCTCCTGTTGCAGCCACTCCAATCCCGCAGGTCACCGTTGAAAACCACGACGATAAAGCATGGCGCGACACCCTG
CTAAAGGTGGCCGCCATTCTCTGTGAGCGCCAGCCGGAGTCACCGCAGGGTTACCGACTGCGCCGCCATGCGCTGTGGCA
AACCATCACCAGTACCCCGCAGGCAGAAAGCGATGGCCGGACCCCACTGGCAGCCTTCCCTGTCGATATGATGGATGATT
ACCTGGCGCGGCTGAACAATGCCGACATGGCGCTGTGGCAGCAGGTGGAAAAAAGCCTGCTGCTGGCCCCGTACTGGCTG
GACGGTCATTACCTCTCAGCACAGACCGCGCTGCGCCTCGGTTATAAACAGGTGGCGGATGCTATCCGTGATGAAGTTAC
CGATTTTCTGGCCCGCCTGCCCGCACTGATCAACCTGTTGTTTAACGACCGCACTCCGTTTGTGTCCGAACAGACGAAAC
AGTGGCTGGCATCATCCGGCTCAGTCAACCAGACCGTCCCGGTTGTACAGACCGATGAAGAATTACAGGCGGCCAAGGCG
TGCTTCGATGAAAACGGGCTGGAAGCCGCGCTGCGGTACCTGGAAAACCTGCCCGAAGGTGATCCCCGCCACCAGTTTCA
CCGCCAGTTTTTCGGCGCGCAGTTACTGGAAGAGGCCGGTATGGTTCAGCTTGCACAACAGCAGTACCGGATGCTCTTCA
GAACAGGATTACACATGATGCTATCCGAATGGGAGCCTTCCCTGCTGAAAGCACTGGAACAAAAACTCACGGCAGAACAG
TAA					