SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP005832
Component protein type	TssB
T6SS ID (Type)	T6SS00551 (Type i3)
Strain	Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S
Replicon	chromosome
Sequence	Protein sequence (181 a.a.); Nucleotide sequence (543 bp)
Reference	[1] Liu J, Guo JT, Li YG, et al. The type VI secretion system gene cluster of Salmonella typhimurium: required for full virulence in mice. J Basic Microbiol. 2013 Jul;53(7):600-7. doi: 10.1002/jobm.201200047. Epub 2012 Sep 7. PMID: 22961625 [2] Pezoa D, Yang HJ, Blondel CJ, et al. The type VI secretion system encoded in SPI-6 plays a role in gastrointestinal colonization and systemic spread of Salmonella enterica serovar Typhimurium in the chicken. PLoS One. 2013 May 14;8(5):e63917. doi: 10.1371/journal.pone.0063917. Print 2013. PMID: 23691117

Experimental investigation has been performed on this T6SS

External database links

Locus tag (Gene)	STM14_RS01955
Coordinate (Strand)	314633..315175 (+)
NCBI ID	WP_000996817.1
RefSeq	NC_016856
Uniprot ID	A0A3Z2NTP6_SALEN, A0A606UHN8_SALTM, A0A7U1KS07_SALET, A0A0H3ND31_SALTS, A0A3Z3GFK8_SALET, A0A4P9T0F1_SALET, A0A5I4KMM1_SALET, A0A3U8PAI7_SALBE, A0A0M0PTI9_SALER, A0A5W1RH43_SALET, A0A2T8QKQ0_SALET, A0A3T2WCQ2_SALET, A0A6C6ZZQ9_SALDC, A0A315GLS2_SALET, A0A6C7I6R3_SALTD, A0A6Y0YUC8_SALET, A0A0F6AX74_SALT1, A0A3U7NHJ4_SALET, A0A636DDZ3_SALET, A0A5R1YIV3_SALIN, A0A3V6BQG0_SALTH, A0A4U1FYX3_SALET, H9L4I8_SALTM, E8XIT7_SALT4, A0A5H9CY08_SALDU, A0A3Z6P2N8_SALTU, Q93IS8_SALTY
KEGG ID	seb:STM474_0284, sev:STMMW_02731, seni:CY43_01370, sey:SL1344_0267, sed:SeD_A0296, stm:STM0273, seo:STM14_0320, sej:STMUK_0275
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
T6SS_VipA	PF05591.14	5.2e-57	12..162

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-180	MAINNSAQKFIARNRAPRVQIEYDVEIYGSEKKIELPFVMAVLADLAGKPREELPPVTDRKFLDIDIDNFNERMKAIAPRVAFAVPNTLTGEGQLMVDITLENMDDFSPAQIARKVDALNQLLEARTQLANLQTYMDGKAGAENLVNKLLQDPTLLKTLANAPKSAATQQDVSADNESAE

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9970	-	-

Protein sequence: 181 a.a.

						>T6CP005832 NC_016856:314633-315175 [Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S] [TssB]
MAINNSAQKFIARNRAPRVQIEYDVEIYGSEKKIELPFVMAVLADLAGKPREELPPVTDRKFLDIDIDNFNERMKAIAPR
VAFAVPNTLTGEGQLMVDITLENMDDFSPAQIARKVDALNQLLEARTQLANLQTYMDGKAGAENLVNKLLQDPTLLKTLA
NAPKSAATQQDVSADNESAE*					

Nucleotide sequence: 543 bp

						>T6CP005832 NC_016856:314633-315175 [Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S] [TssB]
ATGGCTATCAACAATAGCGCGCAGAAATTCATCGCGCGCAACCGCGCGCCGCGCGTGCAGATTGAATATGACGTAGAGAT
TTACGGTTCCGAGAAAAAAATCGAGCTGCCGTTCGTGATGGCGGTGCTGGCCGATCTGGCCGGGAAACCGCGTGAAGAAC
TGCCGCCGGTGACGGATCGCAAATTCCTCGATATTGATATTGATAACTTCAATGAGCGCATGAAAGCCATTGCGCCGCGC
GTGGCGTTCGCTGTGCCGAATACGCTGACGGGTGAAGGTCAGTTGATGGTCGATATCACGCTGGAAAATATGGACGACTT
TTCGCCGGCACAGATTGCCCGCAAGGTGGACGCCCTGAACCAGTTACTGGAAGCCCGCACTCAACTGGCGAACCTCCAGA
CCTACATGGATGGCAAGGCGGGGGCGGAAAATCTGGTCAATAAACTGTTGCAGGACCCGACTCTGCTGAAAACGCTGGCG
AATGCGCCGAAATCGGCCGCTACCCAGCAAGATGTGTCAGCGGATAATGAATCAGCGGAATAA					