Detailed information of component protein


Summary

Component ID T6CP005811
Component protein type TssI
T6SS ID (Type) T6SS00549 insolico (Type Unknown)
Strain Klebsiella pneumoniae subsp. pneumoniae HS11286
Replicon chromosome
Sequence Protein sequence (829 a.a.); Nucleotide sequence (2487 bp)
Reference
-
insolico Bioinformatics investigation has been performed on this T6SS
External database links

Locus tag (Gene) KPHS_32730
Coordinate (Strand) 3257035..3259521 (-)
NCBI ID YP_005227573.1
RefSeq NC_016845
Uniprot ID -
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Phage_GPD PF05954.13 2.4e-66 35..355
DUF2345 PF10106.11 2.6e-52 610..758
T6SS_Vgr PF13296.8 5.1e-32 491..593
Phage_base_V PF04717.14 3.2e-07 405..472
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-828 MDTSSIITGTTLNRYQLDIPSCTASLDVEEFSGAEKLSELYYYTITFTSAEKNIDAAQLLSKPAMLTMGGGALQQLADCKRVHGVVTAFRRISSSEDQSKYQITLEPFLSLLDKQFRSHRFFVNKSVPEVVEQVLQEHHLHDWEYEFYLKQHYPRREQINQYQESDLAFIQRLLAEVGIFYFFTLQEEAQSEVVHFADAQRALTFDKTLPVNSPSGMSDSGAESIWGLSITHNVVEANVTTRDYNPRDAQSVLQSATADMTRGNGEGITYGEVYHYKLRHRERGDKIDPQTETANFYARLDHERFLAHQTLITAISTAAWLAPAQVLTVTDSLPSTLPAPVQDPLLITGTGFTASRREALRVSLLAVPYSETLCWRPPLLPRPKVTGTMTARVTSAKANDIYAWQDASGLYRVKFDADREDKGQGQESMPVRLAKPYGGDVYGFHFPLIQGTEVAIAFHEGDPDRPYIAHALHDSRHVDPVTEKNSTRNVIRTPANNKLRMEDKRGEEHIKLSTEYGGKTQLNLGHNVNAQRELRGEGAELRTDKWVSIRGGAGVFISADKQPSAGDRMLAMEEAIAQLENALGIAKSLASAAESAQALPSDTGNQQTLNDALKELAQPGIVLNAPQGVSISSPQAVRLSSGSASVGIVSQQNTDISALKRFTVAAGEAVSLLARKAGMKLFAAKGKMEIQAQDDALEATAKKDITVTSVEGRVEITAAKELVVNCAGAYIRLSGGNIELGCPGNILLKSANVQKMGKADFRVPPLELPKGFEERFTVKDQKTGEIVPFARYRITTEKGQVFEGRADADGKTASVYTALPESIKIELL


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9860 - -


  Protein sequence: 829 a.a.    

>T6CP005811 NC_016845:c3259521-3257035 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssI]
MDTSSIITGTTLNRYQLDIPSCTASLDVEEFSGAEKLSELYYYTITFTSAEKNIDAAQLLSKPAMLTMGGGALQQLADCK
RVHGVVTAFRRISSSEDQSKYQITLEPFLSLLDKQFRSHRFFVNKSVPEVVEQVLQEHHLHDWEYEFYLKQHYPRREQIN
QYQESDLAFIQRLLAEVGIFYFFTLQEEAQSEVVHFADAQRALTFDKTLPVNSPSGMSDSGAESIWGLSITHNVVEANVT
TRDYNPRDAQSVLQSATADMTRGNGEGITYGEVYHYKLRHRERGDKIDPQTETANFYARLDHERFLAHQTLITAISTAAW
LAPAQVLTVTDSLPSTLPAPVQDPLLITGTGFTASRREALRVSLLAVPYSETLCWRPPLLPRPKVTGTMTARVTSAKAND
IYAWQDASGLYRVKFDADREDKGQGQESMPVRLAKPYGGDVYGFHFPLIQGTEVAIAFHEGDPDRPYIAHALHDSRHVDP
VTEKNSTRNVIRTPANNKLRMEDKRGEEHIKLSTEYGGKTQLNLGHNVNAQRELRGEGAELRTDKWVSIRGGAGVFISAD
KQPSAGDRMLAMEEAIAQLENALGIAKSLASAAESAQALPSDTGNQQTLNDALKELAQPGIVLNAPQGVSISSPQAVRLS
SGSASVGIVSQQNTDISALKRFTVAAGEAVSLLARKAGMKLFAAKGKMEIQAQDDALEATAKKDITVTSVEGRVEITAAK
ELVVNCAGAYIRLSGGNIELGCPGNILLKSANVQKMGKADFRVPPLELPKGFEERFTVKDQKTGEIVPFARYRITTEKGQ
VFEGRADADGKTASVYTALPESIKIELL*

  Nucleotide sequence: 2487 bp    

>T6CP005811 NC_016845:c3259521-3257035 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssI]
ATGGATACCTCTTCAATAATTACCGGCACCACCCTTAACCGTTACCAGCTGGATATTCCTTCATGTACCGCATCGCTGGA
TGTGGAAGAATTCAGTGGGGCAGAAAAACTGAGTGAACTTTATTATTACACTATTACGTTTACCAGCGCAGAGAAAAATA
TTGATGCCGCACAGCTCCTGAGCAAACCCGCCATGCTGACGATGGGCGGCGGCGCACTGCAGCAGTTGGCGGACTGCAAA
CGCGTCCATGGCGTGGTGACTGCCTTCCGGCGTATCAGCAGTTCAGAAGATCAGTCGAAATATCAGATAACCCTCGAACC
CTTCCTCTCCTTACTGGATAAACAGTTTCGCAGCCACCGTTTTTTCGTGAATAAATCGGTGCCGGAGGTGGTGGAGCAGG
TATTGCAGGAACATCACCTGCATGACTGGGAGTATGAGTTTTATCTCAAGCAACACTATCCACGGCGCGAGCAAATTAAT
CAGTATCAGGAGAGCGACCTGGCGTTTATCCAGCGCCTGCTGGCAGAGGTAGGGATATTTTATTTCTTCACCCTGCAGGA
AGAGGCGCAGAGCGAAGTGGTCCACTTCGCCGACGCGCAGCGGGCGCTGACGTTTGATAAGACACTCCCTGTAAACAGCC
CGTCGGGGATGAGCGACAGCGGTGCGGAATCGATATGGGGTCTGAGCATCACCCACAACGTCGTAGAGGCGAACGTTACT
ACCCGGGATTATAACCCCCGCGATGCGCAGAGCGTTCTCCAGTCGGCAACAGCGGATATGACCCGGGGAAATGGTGAAGG
CATCACTTACGGTGAGGTATACCACTATAAGCTTCGCCACCGGGAGCGTGGCGATAAAATCGACCCGCAGACGGAGACCG
CCAACTTCTATGCCCGCCTCGACCATGAGCGTTTTCTGGCTCACCAGACGCTTATTACCGCGATCAGTACTGCAGCCTGG
CTGGCGCCGGCCCAGGTGCTGACCGTTACCGACAGCCTGCCGTCGACCCTGCCTGCGCCCGTACAGGATCCGCTGTTAAT
CACCGGCACCGGTTTTACCGCCAGCCGCCGGGAGGCGCTGCGGGTGTCCCTGCTGGCGGTGCCCTACAGCGAAACATTGT
GCTGGCGTCCGCCGCTGCTGCCGCGCCCGAAGGTGACTGGCACCATGACGGCGCGGGTGACCAGCGCGAAGGCGAATGAT
ATCTATGCCTGGCAAGATGCGTCCGGCCTGTACCGGGTGAAATTTGACGCTGACAGAGAGGATAAAGGGCAGGGTCAGGA
AAGCATGCCGGTGCGTCTCGCCAAACCCTACGGCGGCGACGTGTACGGCTTTCACTTCCCGCTGATCCAGGGCACGGAGG
TGGCGATTGCTTTCCACGAAGGCGATCCCGACCGGCCGTATATTGCGCATGCGCTGCATGACTCGCGGCATGTCGACCCT
GTGACGGAGAAAAACAGCACCCGCAATGTGATTCGTACTCCGGCCAATAATAAGCTGCGAATGGAGGACAAGCGCGGCGA
GGAGCATATCAAGCTCAGCACCGAGTACGGCGGCAAGACGCAGCTGAACCTGGGGCATAACGTGAATGCGCAAAGGGAGT
TGCGGGGCGAGGGTGCGGAACTGCGTACGGATAAATGGGTGAGCATCCGGGGCGGTGCGGGAGTGTTTATCAGTGCGGAT
AAACAGCCTTCGGCAGGCGACAGGATGCTGGCAATGGAGGAGGCGATTGCGCAGCTTGAAAATGCCCTGGGTATTGCGAA
AAGCCTGGCGTCGGCAGCGGAATCGGCTCAGGCCCTGCCATCGGATACCGGCAACCAGCAGACGCTGAACGATGCGCTGA
AAGAGCTGGCGCAGCCGGGGATAGTGCTGAATGCGCCGCAGGGCGTGAGCATCAGCAGTCCGCAGGCGGTACGGTTGTCT
TCGGGTAGCGCCAGCGTGGGGATTGTGTCACAGCAGAATACGGACATCAGTGCGCTGAAACGTTTTACGGTGGCGGCGGG
AGAAGCCGTCAGCCTGCTGGCGCGAAAGGCGGGGATGAAGCTGTTTGCGGCGAAGGGAAAGATGGAAATCCAGGCGCAGG
ATGATGCGCTGGAGGCGACGGCGAAAAAGGATATCACAGTTACCAGCGTGGAAGGCCGGGTGGAAATCACGGCGGCGAAG
GAACTGGTGGTGAACTGTGCGGGAGCGTATATCAGGCTAAGTGGTGGCAATATCGAGCTGGGCTGCCCGGGGAATATTCT
GCTGAAATCGGCCAATGTGCAGAAAATGGGTAAGGCGGATTTTCGGGTGCCTCCGCTGGAATTGCCTAAAGGGTTCGAAG
AGCGTTTTACTGTCAAAGATCAGAAGACCGGTGAAATTGTTCCGTTTGCCCGTTACCGCATCACCACTGAAAAAGGCCAG
GTATTCGAAGGCCGGGCAGATGCTGATGGGAAAACGGCCAGCGTTTATACCGCATTGCCTGAATCAATAAAAATAGAGCT
ACTGTGA