Detailed information of component protein


Summary

Component ID T6CP005810
Component protein type TssM
T6SS ID (Type) T6SS00549 insolico (Type Unknown)
Strain Klebsiella pneumoniae subsp. pneumoniae HS11286
Replicon chromosome
Sequence Protein sequence (1137 a.a.); Nucleotide sequence (3411 bp)
Reference
-
insolico Bioinformatics investigation has been performed on this T6SS
External database links

Locus tag (Gene) KPHS_32500
Coordinate (Strand) 3240404..3243814 (-)
NCBI ID YP_005227550.1
RefSeq NC_016845
Uniprot ID -
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 5.5e-69 417..732
IcmF_C PF06744.14 1.2e-19 988..1094
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-6 MNIPGN
Transmembrane helix 7-29 GLGRFGLAGLTLAGMAAIWWGIT
Outside 30-43 RYGGMLNINTRGEQ
Transmembrane helix 44-63 VLAFVQVCMALVFVFYLPAM
Inside 64-367 SRRVKESLYRRQSQQDSVLPGEEGRVALTPPHHITVGEIRQTLRYQYGRAWSRKVRILLIIGSVRDVEQLTPKLTQELWQEDQGTLLLWGGDPGAAVDNAWFTALRKLRYRPADGMVWVTSGFDGVLTTMNRTKPRLTPDEMDSVSHSLKLRFEALGWKLPLYVWSLYEGGNEKNGRITQPVGCLLPAGCTPQIVAEQFTALASLLIEQGIQQICGQPQHNFLLALADQLTRKPETVTEPLSVLLNPYRPQPLAGVVFSEASVEAGRSVRHHWGRDNRWETIPDSVLWLPAGLRPRKQGVNWMR
Transmembrane helix 368-390 GMSVAAAALMLLWAASMTVSFIS
Outside 391-1136 NRHLVAIAQQQVQQASAGKQPLAVRLYALSALQKTLSQLEYRSQHGAPWYLRAGLSQNDDLLAALFPRYGEMAQPLLRDAAAHHLEEQLTAFVQLPPDSPLREKMTKTAYGQLKQYLMLTRPEKMDAAWFATTLMQDWPQRSGIADAVWQGSGPSLLAFYAASLASHPQWRLPVDDGLVSQVRTRLIRQLGQRNSESTLYQKMLAQVANQYADMRLADMTADTDASRLFSTDEVVPGMFTRQAWEQAVQPAIEKVVAERRDEMDWVLSDTKQTAAQSTSPEALRARLAERYFADFSGAWLDFLNSLRWQRAATLSDAIDQLTLMADVRQSPLVALMNTLSVQGRTGQTGEAIADSLVKSARQLFNRDNPPVIDQRSGARGPLDATFGPVLALLDNRDGGTPTSRLSLQTFLTRVTQVRLRLQQVTNATDPQAMTRLLAQTVFQGKAVDLTETRDYGSLVAAGLGQEWSGFGQTLFVRPMEQAWQQVLTPAAESLNAQWRSAVVEDWNSAFGGRYPFKNTSSEVSLPLLAKYLNSETGRIARFLQTRLNGVLHKEGSRWMADSINAQGLTFNPAFLQAMNTLSHLSDVAFANGEAGLHFALRPGTADGVMQTELVIDSQKLVYMNQMPVWRRFSWPADTEAPGASLSWVSTRAGTRQYGDFPGAWGWIRLLDKAVVSAYPGTSSSWSLSWKAPDGLLLNYTLRTEAGEGPLALLALRNFTLPETIFSVRASAERVPLTDDIPGEEGY


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9912 - -


  Protein sequence: 1137 a.a.    

>T6CP005810 NC_016845:c3243814-3240404 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssM]
MNIPGNGLGRFGLAGLTLAGMAAIWWGITRYGGMLNINTRGEQVLAFVQVCMALVFVFYLPAMSRRVKESLYRRQSQQDS
VLPGEEGRVALTPPHHITVGEIRQTLRYQYGRAWSRKVRILLIIGSVRDVEQLTPKLTQELWQEDQGTLLLWGGDPGAAV
DNAWFTALRKLRYRPADGMVWVTSGFDGVLTTMNRTKPRLTPDEMDSVSHSLKLRFEALGWKLPLYVWSLYEGGNEKNGR
ITQPVGCLLPAGCTPQIVAEQFTALASLLIEQGIQQICGQPQHNFLLALADQLTRKPETVTEPLSVLLNPYRPQPLAGVV
FSEASVEAGRSVRHHWGRDNRWETIPDSVLWLPAGLRPRKQGVNWMRGMSVAAAALMLLWAASMTVSFISNRHLVAIAQQ
QVQQASAGKQPLAVRLYALSALQKTLSQLEYRSQHGAPWYLRAGLSQNDDLLAALFPRYGEMAQPLLRDAAAHHLEEQLT
AFVQLPPDSPLREKMTKTAYGQLKQYLMLTRPEKMDAAWFATTLMQDWPQRSGIADAVWQGSGPSLLAFYAASLASHPQW
RLPVDDGLVSQVRTRLIRQLGQRNSESTLYQKMLAQVANQYADMRLADMTADTDASRLFSTDEVVPGMFTRQAWEQAVQP
AIEKVVAERRDEMDWVLSDTKQTAAQSTSPEALRARLAERYFADFSGAWLDFLNSLRWQRAATLSDAIDQLTLMADVRQS
PLVALMNTLSVQGRTGQTGEAIADSLVKSARQLFNRDNPPVIDQRSGARGPLDATFGPVLALLDNRDGGTPTSRLSLQTF
LTRVTQVRLRLQQVTNATDPQAMTRLLAQTVFQGKAVDLTETRDYGSLVAAGLGQEWSGFGQTLFVRPMEQAWQQVLTPA
AESLNAQWRSAVVEDWNSAFGGRYPFKNTSSEVSLPLLAKYLNSETGRIARFLQTRLNGVLHKEGSRWMADSINAQGLTF
NPAFLQAMNTLSHLSDVAFANGEAGLHFALRPGTADGVMQTELVIDSQKLVYMNQMPVWRRFSWPADTEAPGASLSWVST
RAGTRQYGDFPGAWGWIRLLDKAVVSAYPGTSSSWSLSWKAPDGLLLNYTLRTEAGEGPLALLALRNFTLPETIFSVRAS
AERVPLTDDIPGEEGY*

  Nucleotide sequence: 3411 bp    

>T6CP005810 NC_016845:c3243814-3240404 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssM]
ATGAATATACCGGGTAATGGCCTGGGCCGGTTTGGCCTGGCCGGGCTTACGTTGGCCGGGATGGCTGCAATATGGTGGGG
GATCACCCGCTATGGCGGCATGCTGAATATCAATACGCGGGGCGAGCAGGTACTGGCGTTTGTCCAGGTCTGTATGGCGT
TGGTATTTGTTTTTTACCTTCCTGCAATGTCCCGCCGTGTGAAGGAGAGTTTATATCGCCGGCAGTCGCAGCAGGACAGC
GTCTTACCCGGCGAAGAAGGGCGCGTGGCGCTGACACCTCCCCATCATATTACGGTGGGGGAAATTCGCCAGACTCTACG
CTATCAGTATGGACGCGCCTGGTCCCGCAAAGTCCGTATTCTGCTGATAATTGGCTCAGTCAGAGACGTAGAACAACTGA
CCCCAAAGCTCACGCAGGAACTCTGGCAGGAAGATCAGGGTACATTATTGCTGTGGGGTGGAGACCCTGGGGCAGCGGTA
GATAACGCCTGGTTCACAGCGCTGCGTAAACTGCGTTATCGCCCGGCTGATGGTATGGTGTGGGTAACATCGGGCTTTGA
CGGCGTTTTGACAACGATGAACAGAACGAAGCCCAGGCTCACGCCAGATGAAATGGACAGTGTGTCTCACTCTCTAAAGC
TACGCTTCGAAGCTCTTGGCTGGAAACTACCCCTATACGTCTGGTCGCTGTATGAGGGGGGCAACGAAAAAAATGGACGT
ATCACTCAGCCTGTAGGCTGCCTGTTACCTGCAGGTTGTACGCCGCAAATAGTTGCCGAACAGTTCACTGCCCTGGCGTC
GTTACTGATAGAGCAGGGCATCCAGCAGATATGCGGGCAACCACAGCACAATTTTTTACTCGCGCTGGCCGATCAGTTGA
CCCGTAAACCGGAAACGGTGACGGAGCCGTTATCGGTATTGCTTAATCCTTACCGCCCGCAGCCGCTGGCCGGGGTGGTA
TTTAGTGAGGCGTCAGTAGAGGCTGGTCGCAGTGTCCGTCATCACTGGGGACGGGATAACCGCTGGGAAACGATACCAGA
CTCAGTGCTGTGGTTGCCAGCCGGTCTACGTCCGCGCAAACAGGGAGTCAACTGGATGCGTGGGATGAGCGTGGCCGCCG
CCGCCCTGATGTTACTCTGGGCCGCCTCAATGACAGTCTCTTTTATCTCCAACCGCCACCTGGTGGCGATCGCACAGCAG
CAGGTGCAGCAGGCCTCGGCGGGAAAACAGCCGCTGGCCGTACGCCTGTATGCGCTCTCCGCGTTACAGAAAACGCTTTC
TCAACTGGAATACCGCTCGCAGCACGGAGCGCCGTGGTACCTCCGCGCTGGCCTCAGTCAGAACGATGACCTGCTGGCGG
CGCTGTTCCCGCGCTACGGGGAGATGGCGCAACCGCTGCTGCGCGATGCGGCGGCGCATCATCTGGAAGAGCAGCTCACC
GCCTTCGTGCAGCTGCCGCCGGACAGCCCACTGCGTGAGAAGATGACGAAGACCGCTTACGGACAACTGAAACAATATCT
GATGTTGACCCGCCCGGAAAAAATGGACGCCGCGTGGTTCGCCACTACGCTAATGCAGGACTGGCCGCAGCGCTCAGGCA
TCGCCGACGCCGTCTGGCAGGGCAGCGGCCCTTCGCTGCTGGCATTTTATGCCGCCAGCCTGGCATCGCATCCGCAGTGG
CGTCTGCCTGTCGATGACGGTCTGGTCAGCCAGGTGCGCACACGGTTAATTCGCCAACTGGGCCAGCGCAACAGTGAGTC
CACGCTTTACCAGAAGATGCTCGCGCAGGTGGCGAATCAGTATGCCGATATGCGCCTGGCGGATATGACTGCCGACACCG
ATGCTTCGCGTCTGTTCAGCACTGATGAGGTGGTGCCGGGAATGTTTACCCGTCAGGCCTGGGAGCAGGCCGTGCAGCCG
GCCATTGAGAAAGTGGTCGCGGAACGCCGCGATGAAATGGACTGGGTGCTGAGCGATACGAAGCAGACTGCCGCGCAGTC
GACGTCGCCGGAAGCTCTGCGAGCCAGGCTGGCGGAGCGTTATTTCGCTGATTTCAGCGGCGCCTGGCTGGATTTCCTCA
ACAGTCTGCGCTGGCAGCGCGCGGCGACCCTCTCCGATGCTATCGACCAGCTGACCCTGATGGCCGATGTGCGCCAGTCG
CCGCTGGTGGCGCTGATGAACACCCTGAGCGTGCAGGGGCGAACCGGCCAGACCGGGGAAGCCATCGCCGATTCGCTGGT
CAAATCGGCCAGGCAGCTGTTCAACCGTGACAACCCGCCCGTCATCGATCAACGGTCCGGCGCGCGCGGTCCTCTGGATG
CCACCTTCGGCCCCGTACTGGCGCTGCTGGACAATCGCGACGGCGGGACCCCCACCAGCCGTCTTAGCCTGCAGACCTTC
CTGACCCGCGTCACCCAGGTGCGTCTGCGCCTGCAGCAGGTCACCAACGCCACCGATCCGCAGGCGATGACCCGCCTGCT
TGCGCAGACGGTATTCCAGGGCAAGGCCGTGGATTTAACCGAAACGCGCGACTACGGCAGCCTGGTGGCGGCGGGGCTGG
GCCAGGAGTGGAGTGGATTTGGGCAAACGCTGTTTGTTCGCCCGATGGAACAGGCCTGGCAGCAGGTGCTGACCCCGGCG
GCGGAAAGTCTCAACGCCCAGTGGCGCAGCGCGGTGGTGGAGGACTGGAATAGCGCTTTTGGCGGTCGCTACCCCTTTAA
AAATACCAGCAGTGAAGTCTCTCTGCCGCTGCTGGCAAAATACCTCAACAGCGAGACCGGGCGCATCGCCCGCTTTCTGC
AGACCCGGCTGAACGGCGTACTGCATAAAGAGGGGAGCCGCTGGATGGCGGACAGTATCAATGCCCAGGGGCTGACGTTT
AACCCGGCCTTTCTGCAGGCGATGAATACCCTGAGTCATCTCTCTGACGTCGCGTTCGCCAACGGCGAAGCGGGATTGCA
TTTTGCGCTACGTCCCGGCACCGCGGACGGCGTGATGCAGACGGAGCTGGTCATCGACAGTCAGAAACTTGTCTATATGA
ACCAGATGCCGGTCTGGCGGCGGTTCAGCTGGCCCGCTGACACCGAAGCGCCGGGCGCCAGTCTGAGCTGGGTCAGTACC
CGGGCGGGCACCCGCCAGTATGGCGATTTCCCGGGCGCCTGGGGGTGGATCCGTCTGCTGGATAAGGCGGTGGTCAGCGC
TTATCCCGGAACGAGCAGCAGCTGGAGCCTGAGCTGGAAAGCGCCGGATGGTCTGTTGCTGAACTACACGCTGCGTACCG
AGGCGGGGGAAGGACCGCTGGCGCTGCTGGCGCTGCGAAACTTTACGCTACCGGAGACGATATTCAGCGTGCGCGCGTCT
GCTGAACGTGTTCCGCTGACCGACGATATACCCGGCGAAGAGGGATACTGA