Detailed information of component protein


Summary

Component ID T6CP005804
Component protein type TssF
T6SS ID (Type) T6SS00548 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae HS11286
Replicon chromosome
Sequence Protein sequence (585 a.a.); Nucleotide sequence (1755 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KPHS_23170
Coordinate (Strand) 2349937..2351691 (+)
NCBI ID YP_005226617.1
RefSeq NC_016845
Uniprot ID A0A0H3GMD4_KLEPH
KEGG ID kpm:KPHS_23170
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
T6SS_TssF PF05947.14 1.4e-178 1..581
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-584 MDDLTLRYYDAEMRYLLEAGEEFARAHPEQAAMLNLDKAGARDPFVERLFEGFAFLMGRMREKLDDDLPELTEGVVSLLWPHYLRTIPSMSVVEFTPDWPEMKEPMTMAKGFEVLSRPIGEKGTRCRYTTTKAIALQPLSLERVQLATDTDGRSVITLRFTCSQLTDWRRVDLSHIPLYCNADAPLACAMHEAFTLNVARMWLRMPEEVDRRPLDGYFSALGFGEDDGLWPEDGRSFRGYQLLLEYFTFREKFMFIDLRGLETVAFPAGLAWFEIDVVLAERWEHDFRFSEKQLRLHCVPVINLFPLESDPLTINSLQTEYPLRPMRVQDGHTEIYTVDSVISSHQQVYAPFSSFRHKGGMMRHDAADYYYHTRVRRGPSGLYNTWLIVGGEAFDNHTVPEDESLSLTLTGTNGQLPRRALQSTVLDTVMKTTSASIAVRNLCAPTLPCYPPAQDRFHWRVLSHLGSSFLSLMDNAEVLRGTLALYEWTDSEMNRRRLEAILDVKHRATERFAQGHLVRGVQIEVTLDSHGFAGRGDICLFGEMLSRFFALYTDIYLFNRLIIILQPTGERLEWEEKHSRRIPG


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9977 - -


  Protein sequence: 585 a.a.    

>T6CP005804 NC_016845:2349937-2351691 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssF]
MDDLTLRYYDAEMRYLLEAGEEFARAHPEQAAMLNLDKAGARDPFVERLFEGFAFLMGRMREKLDDDLPELTEGVVSLLW
PHYLRTIPSMSVVEFTPDWPEMKEPMTMAKGFEVLSRPIGEKGTRCRYTTTKAIALQPLSLERVQLATDTDGRSVITLRF
TCSQLTDWRRVDLSHIPLYCNADAPLACAMHEAFTLNVARMWLRMPEEVDRRPLDGYFSALGFGEDDGLWPEDGRSFRGY
QLLLEYFTFREKFMFIDLRGLETVAFPAGLAWFEIDVVLAERWEHDFRFSEKQLRLHCVPVINLFPLESDPLTINSLQTE
YPLRPMRVQDGHTEIYTVDSVISSHQQVYAPFSSFRHKGGMMRHDAADYYYHTRVRRGPSGLYNTWLIVGGEAFDNHTVP
EDESLSLTLTGTNGQLPRRALQSTVLDTVMKTTSASIAVRNLCAPTLPCYPPAQDRFHWRVLSHLGSSFLSLMDNAEVLR
GTLALYEWTDSEMNRRRLEAILDVKHRATERFAQGHLVRGVQIEVTLDSHGFAGRGDICLFGEMLSRFFALYTDIYLFNR
LIIILQPTGERLEWEEKHSRRIPG*

  Nucleotide sequence: 1755 bp    

>T6CP005804 NC_016845:2349937-2351691 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssF]
ATGGACGATTTAACCCTGCGTTATTACGACGCTGAAATGCGCTACCTGCTGGAAGCGGGTGAAGAGTTTGCCCGCGCTCA
TCCTGAGCAGGCGGCAATGCTCAATCTCGACAAAGCGGGCGCTCGCGACCCCTTTGTCGAGCGTCTGTTTGAAGGTTTTG
CCTTCCTGATGGGCCGCATGCGCGAGAAACTCGATGACGATCTGCCTGAGCTGACCGAAGGCGTGGTCAGTCTGCTGTGG
CCACATTATTTACGTACCATTCCCTCGATGTCGGTCGTGGAGTTCACCCCCGACTGGCCGGAAATGAAAGAGCCGATGAC
GATGGCCAAAGGCTTTGAAGTGCTTTCCCGGCCGATCGGTGAAAAGGGCACGCGCTGCCGGTACACCACCACCAAAGCGA
TCGCTCTGCAGCCGTTATCCCTGGAACGCGTCCAGCTGGCCACCGATACGGATGGCCGGTCGGTGATCACGCTGCGCTTT
ACCTGCAGCCAGCTGACGGACTGGCGCCGGGTCGATCTCAGTCATATCCCGCTGTACTGCAACGCCGATGCGCCGCTGGC
CTGCGCCATGCACGAGGCCTTTACCCTCAATGTGGCCCGGATGTGGCTGCGCATGCCCGAAGAGGTGGACAGAAGGCCGC
TGGACGGGTATTTCAGCGCGCTGGGATTTGGCGAGGATGACGGCCTCTGGCCTGAAGATGGCCGCAGTTTTCGCGGTTAT
CAGCTGCTGCTGGAGTATTTTACCTTCCGCGAAAAGTTCATGTTCATCGATCTGCGCGGGCTGGAGACGGTGGCTTTTCC
GGCCGGACTGGCGTGGTTTGAAATCGACGTCGTGCTGGCGGAACGCTGGGAACATGACTTCCGCTTCAGCGAAAAGCAGC
TGCGCCTGCACTGCGTGCCAGTGATCAACCTGTTTCCGCTGGAGTCCGATCCGCTGACCATCAATTCCCTGCAGACCGAA
TACCCGCTGCGCCCGATGCGCGTGCAGGACGGCCACACCGAAATTTACACCGTCGATTCCGTGATCTCCTCACACCAGCA
GGTTTACGCGCCGTTCTCAAGTTTTCGCCACAAAGGCGGCATGATGCGTCATGACGCGGCGGACTATTACTATCATACCC
GGGTGCGCCGTGGCCCCTCCGGGCTGTACAACACCTGGCTTATCGTCGGCGGAGAAGCCTTTGATAATCATACCGTACCG
GAAGATGAAAGCCTGTCGCTGACCCTCACCGGAACCAACGGCCAGCTGCCGCGTCGCGCGCTGCAGAGCACCGTGCTCGA
TACGGTGATGAAAACCACTTCCGCCAGTATTGCAGTGCGTAACCTCTGCGCGCCGACGCTGCCGTGCTATCCCCCCGCCC
AGGACCGTTTTCACTGGCGGGTGCTGAGCCATCTGGGCAGCAGTTTTCTTTCCCTGATGGATAACGCGGAGGTCCTGCGC
GGCACCCTGGCGCTGTATGAATGGACCGACAGCGAGATGAATCGTCGGCGTCTGGAAGCCATCCTCGACGTGAAGCACCG
CGCAACAGAGCGCTTTGCACAGGGCCATCTGGTGCGCGGCGTGCAGATTGAAGTCACCCTCGACAGTCACGGCTTTGCCG
GACGTGGCGATATATGCCTGTTTGGCGAGATGCTTAGCCGCTTCTTCGCGCTCTACACCGACATCTACTTGTTCAACCGC
CTGATTATCATTCTGCAACCAACCGGAGAACGACTGGAATGGGAAGAGAAGCACAGCCGCCGCATTCCCGGCTGA