Detailed information of component protein


Summary

Component ID T6CP005803
Component protein type TssM
T6SS ID (Type) T6SS00548 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae HS11286
Replicon chromosome
Sequence Protein sequence (1142 a.a.); Nucleotide sequence (3426 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KPHS_23140
Coordinate (Strand) 2344840..2348265 (+)
NCBI ID YP_005226614.1
RefSeq NC_016845
Uniprot ID A0A0H3GS02_KLEPH
KEGG ID kpm:KPHS_23140
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 2.9e-60 416..733
IcmF_C PF06744.14 1.3e-21 992..1096
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-12 MDNVNKPAAISV
Transmembrane helix 13-35 AATVIVCIAAVTLLVLLGGLAWW
Outside 36-54 LWAMDRATQWETLRPLIAT
Transmembrane helix 55-77 GFIIWGMALSLLVLGFMAFRLLI
Inside 78-367 KDKVKPSAAPVRQPTRPAGGEALYAPLKKHLHARYRLHWRRKVRLLLVTGDEAAIEQLVPGLRQQRWLEGQRTVLIYGGSLLSEPDSEQYAALRKLRHGRPLDGIVRVMPSSLTLTPQISESDLRGLEKISELLGYAAPVWLWKLCDSEWPQADRAEQAVGVSFPLRATEEDVARQLAQMLPTLREQGMHQIAADTRHDFLLRLGQQLIDGEIAQWRRQLAPWLTASRQRLALRGLMFSLPEPRTVDPYQEADALPASQPHLLTLPATWQGIVDDCRRLRGHHVGMAWER
Transmembrane helix 368-390 GLACGLLAIFGLWAAGLLLSFAL
Outside 391-1141 NYSQIASVAGKARDLVAHPSVSDYQLTALHALRNEAGRLVHDGQNGAPWYRRFGLDHHQQLLDAVLPWYGVANHRLIRDPANAALQQALSALVNSAPNSDQRAQLAKPGYDQLKAWLMMARPDKADGAFFAQTMKTVQPTRMGISTGLWQSLAPDLWAFYLSLLPERPEWKIIPDAQRVSQSRQVLLQQLGRRNAESTLYENMLKSVRRNFADVSLEDMTSGTDARRLFTTNEVVPGMFTRQAWEGGIQQAIDKAASSRREEIDWVLSDSRKTMSTDLSPEALKARLTRRYFTDFAGSWLNFLNSLRLNPATTIADVTDQLTLISGVRQSPLIALMNTLAWQGQAGQQREGLSDSLIKSAKDLVGGKDKPVIDQSAAGPQGPLDDTFGPLLQLMGKNTGSNVMSADSTLSLQTYLTRITRVRLRLQQVANASDPQEMMQTLAQTVFLGKSVDLTDTQQYGSLISASLGEEWSGFGNTLFVQPLTQAWETVLLPSAASLNDKWRRSVVANWHTAFDGRFPFAASKSDASLPMLAEFVRKDSGRIERFLTTELNGVLHKEGSQWVPDKVNSHGLVFNPAFLRAINQLSQLSDILFTDGSQGISFELQARPAPEVVETQLTIDGQKLRYFNQMADWQTFRWPGETYKPGTLLTWTTVNAGTRLFGDYSGTWGFIRWLEQGKRHPLDRSQWMMSFSAPDGRTLQWVLRSQLGSGPLALLALRGLTLPDQIFTVDAAESAQALTTGVGNSDMDEME


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9951 - -


  Protein sequence: 1142 a.a.    

>T6CP005803 NC_016845:2344840-2348265 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssM]
MDNVNKPAAISVAATVIVCIAAVTLLVLLGGLAWWLWAMDRATQWETLRPLIATGFIIWGMALSLLVLGFMAFRLLIKDK
VKPSAAPVRQPTRPAGGEALYAPLKKHLHARYRLHWRRKVRLLLVTGDEAAIEQLVPGLRQQRWLEGQRTVLIYGGSLLS
EPDSEQYAALRKLRHGRPLDGIVRVMPSSLTLTPQISESDLRGLEKISELLGYAAPVWLWKLCDSEWPQADRAEQAVGVS
FPLRATEEDVARQLAQMLPTLREQGMHQIAADTRHDFLLRLGQQLIDGEIAQWRRQLAPWLTASRQRLALRGLMFSLPEP
RTVDPYQEADALPASQPHLLTLPATWQGIVDDCRRLRGHHVGMAWERGLACGLLAIFGLWAAGLLLSFALNYSQIASVAG
KARDLVAHPSVSDYQLTALHALRNEAGRLVHDGQNGAPWYRRFGLDHHQQLLDAVLPWYGVANHRLIRDPANAALQQALS
ALVNSAPNSDQRAQLAKPGYDQLKAWLMMARPDKADGAFFAQTMKTVQPTRMGISTGLWQSLAPDLWAFYLSLLPERPEW
KIIPDAQRVSQSRQVLLQQLGRRNAESTLYENMLKSVRRNFADVSLEDMTSGTDARRLFTTNEVVPGMFTRQAWEGGIQQ
AIDKAASSRREEIDWVLSDSRKTMSTDLSPEALKARLTRRYFTDFAGSWLNFLNSLRLNPATTIADVTDQLTLISGVRQS
PLIALMNTLAWQGQAGQQREGLSDSLIKSAKDLVGGKDKPVIDQSAAGPQGPLDDTFGPLLQLMGKNTGSNVMSADSTLS
LQTYLTRITRVRLRLQQVANASDPQEMMQTLAQTVFLGKSVDLTDTQQYGSLISASLGEEWSGFGNTLFVQPLTQAWETV
LLPSAASLNDKWRRSVVANWHTAFDGRFPFAASKSDASLPMLAEFVRKDSGRIERFLTTELNGVLHKEGSQWVPDKVNSH
GLVFNPAFLRAINQLSQLSDILFTDGSQGISFELQARPAPEVVETQLTIDGQKLRYFNQMADWQTFRWPGETYKPGTLLT
WTTVNAGTRLFGDYSGTWGFIRWLEQGKRHPLDRSQWMMSFSAPDGRTLQWVLRSQLGSGPLALLALRGLTLPDQIFTVD
AAESAQALTTGVGNSDMDEME*

  Nucleotide sequence: 3426 bp    

>T6CP005803 NC_016845:2344840-2348265 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssM]
ATGGACAACGTCAATAAACCTGCCGCTATCTCTGTGGCGGCTACGGTTATCGTCTGTATTGCTGCGGTCACGCTTCTGGT
GCTCCTGGGCGGGCTGGCATGGTGGCTATGGGCGATGGATCGTGCCACGCAGTGGGAAACGCTGCGCCCGCTTATCGCCA
CGGGCTTTATTATCTGGGGGATGGCACTCAGCCTGCTGGTACTGGGGTTTATGGCCTTTCGACTGCTGATAAAAGATAAG
GTTAAGCCTTCAGCAGCGCCTGTGCGGCAACCCACCAGGCCTGCCGGGGGCGAAGCCCTTTATGCCCCGCTGAAAAAGCA
CCTTCACGCACGTTACCGCCTGCACTGGCGGCGCAAAGTCCGCCTGCTTTTAGTCACCGGCGACGAGGCGGCAATCGAAC
AACTGGTGCCTGGCCTGCGTCAGCAGCGCTGGCTGGAGGGCCAGCGTACCGTTCTGATTTACGGCGGCAGTCTGCTCTCC
GAGCCCGACAGTGAGCAATATGCCGCGCTGCGCAAGCTGCGCCACGGTCGTCCTCTGGATGGGATTGTGCGGGTGATGCC
GTCGTCTCTCACCCTGACGCCGCAGATAAGCGAGAGCGACCTGCGCGGGCTGGAAAAAATCAGCGAACTGCTGGGCTATG
CCGCCCCGGTCTGGTTATGGAAACTGTGCGACAGTGAGTGGCCGCAGGCTGACCGCGCGGAGCAGGCGGTAGGGGTTAGC
TTCCCGTTGCGCGCCACTGAGGAAGATGTCGCCCGTCAGCTTGCGCAGATGTTGCCGACGCTACGGGAGCAGGGGATGCA
CCAGATCGCAGCAGATACCCGCCACGACTTCCTGCTGCGTCTGGGGCAGCAGCTTATCGACGGGGAGATCGCACAATGGC
GCCGGCAGCTGGCGCCGTGGCTGACCGCCTCGCGGCAGCGGCTTGCGCTGCGAGGCCTGATGTTTAGCCTGCCAGAGCCT
CGTACCGTAGATCCGTATCAGGAAGCTGATGCCCTGCCTGCGAGCCAGCCTCACCTCCTGACGCTTCCCGCCACCTGGCA
GGGGATCGTCGATGACTGCCGCCGTTTACGCGGGCATCACGTGGGAATGGCATGGGAGCGGGGCCTGGCGTGCGGTCTGC
TGGCCATCTTCGGCCTGTGGGCGGCGGGACTGCTGCTCTCCTTTGCCCTCAATTACAGTCAGATTGCTTCGGTAGCGGGA
AAAGCCCGCGACCTGGTGGCCCACCCCTCCGTTTCTGACTATCAACTGACGGCCCTCCATGCCCTGCGCAATGAGGCCGG
CCGTCTCGTGCACGATGGGCAGAATGGCGCTCCCTGGTATCGGCGCTTTGGTCTGGACCATCATCAGCAACTATTAGACG
CCGTCCTGCCCTGGTACGGTGTGGCGAATCATCGCCTGATACGTGACCCGGCCAATGCCGCGTTGCAGCAGGCGCTCAGC
GCGCTGGTCAACTCCGCCCCCAATAGCGACCAACGAGCCCAGCTGGCGAAACCGGGCTATGACCAGCTGAAAGCCTGGCT
GATGATGGCTCGTCCGGATAAAGCCGATGGCGCATTTTTTGCGCAGACCATGAAAACGGTCCAGCCGACGCGAATGGGGA
TCTCGACCGGTCTGTGGCAAAGTCTGGCGCCGGATTTGTGGGCCTTTTATCTCTCCCTGCTGCCCGAGCGGCCAGAGTGG
AAGATCATCCCGGATGCGCAACGGGTGAGTCAGAGCCGTCAGGTTCTGTTGCAGCAGCTAGGTCGCCGCAATGCCGAAAG
CACCTTATATGAGAACATGCTCAAATCCGTGCGTCGTAATTTTGCCGATGTATCGCTGGAAGACATGACCAGTGGCACCG
ACGCGCGCCGGCTGTTTACCACCAATGAAGTGGTCCCGGGGATGTTTACCCGCCAGGCATGGGAAGGCGGCATTCAGCAG
GCCATTGATAAGGCAGCCAGCTCGCGCCGGGAGGAAATCGACTGGGTGCTGAGCGATTCGCGCAAAACGATGTCGACAGA
CCTGTCGCCGGAGGCGCTGAAAGCGCGTCTGACCCGACGCTACTTCACCGATTTCGCCGGCAGCTGGCTGAATTTTCTCA
ACAGTCTGCGACTCAACCCAGCGACCACCATTGCCGATGTTACCGACCAGCTCACGCTGATAAGCGGTGTCCGCCAGTCG
CCGCTGATTGCCCTGATGAATACCCTTGCCTGGCAGGGGCAGGCGGGGCAACAAAGGGAGGGGCTGTCGGACAGCCTTAT
TAAATCGGCCAAAGATCTGGTGGGCGGGAAAGACAAGCCGGTCATCGACCAGTCGGCAGCCGGCCCGCAGGGGCCTCTGG
ATGACACGTTCGGACCACTGCTCCAGCTGATGGGGAAAAACACGGGCAGCAACGTCATGTCGGCCGATAGCACCCTGAGC
CTGCAAACCTATCTGACCCGTATCACCCGCGTGCGCCTGCGCCTGCAGCAGGTTGCGAATGCCTCCGATCCGCAGGAGAT
GATGCAGACCCTGGCGCAGACCGTCTTCCTGGGGAAAAGCGTCGACCTGACCGACACGCAACAGTACGGTAGCCTGATTT
CGGCAAGCCTTGGCGAAGAGTGGAGTGGCTTCGGTAATACTCTGTTTGTGCAGCCGCTGACTCAGGCCTGGGAAACCGTG
CTTCTGCCGTCGGCGGCCAGTCTGAATGATAAATGGCGCCGTTCGGTGGTCGCCAACTGGCACACCGCCTTTGACGGACG
CTTTCCGTTTGCCGCCAGCAAAAGCGATGCCTCCCTGCCGATGCTGGCTGAGTTTGTGCGCAAAGACAGCGGGCGAATCG
AACGTTTTCTCACGACGGAGCTGAACGGTGTCCTGCATAAAGAAGGCAGTCAATGGGTGCCGGATAAGGTCAACAGTCAC
GGCCTGGTCTTTAATCCGGCCTTTCTGCGCGCGATCAACCAGCTAAGCCAGCTGTCCGACATTCTTTTCACCGACGGCAG
CCAGGGGATCAGCTTTGAGTTACAGGCCAGGCCTGCCCCGGAGGTTGTCGAGACACAGCTGACGATAGACGGCCAAAAGT
TGCGTTATTTCAATCAGATGGCCGACTGGCAGACTTTCCGCTGGCCGGGGGAGACGTATAAACCCGGCACTCTGCTGACC
TGGACCACCGTCAATGCGGGCACGCGTCTGTTCGGTGACTACAGCGGTACCTGGGGCTTTATTCGCTGGCTGGAGCAGGG
TAAACGCCATCCGCTGGATCGCAGCCAGTGGATGATGAGCTTCTCCGCCCCGGATGGCCGCACCCTGCAGTGGGTATTGC
GCTCCCAGCTTGGGAGCGGCCCGCTGGCGCTTCTGGCGCTCCGCGGATTGACCCTGCCGGATCAGATTTTCACTGTCGAT
GCGGCTGAGAGCGCACAGGCCCTGACGACGGGGGTAGGGAATAGTGACATGGATGAGATGGAATAA