Detailed information of component protein


Summary

Component ID T6CP005802
Component protein type TssI
T6SS ID (Type) T6SS00548 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae HS11286
Replicon chromosome
Sequence Protein sequence (790 a.a.); Nucleotide sequence (2370 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) KPHS_23040
Coordinate (Strand) 2335474..2337843 (+)
NCBI ID YP_005226604.1
RefSeq NC_016845
Uniprot ID A0A0H3GRZ3_KLEPH
KEGG ID kpm:KPHS_23040
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Phage_GPD PF05954.13 1.6e-60 31..353
DUF2345 PF10106.11 3.5e-43 610..755
T6SS_Vgr PF13296.8 1.7e-32 490..585
Phage_base_V PF04717.14 3e-09 404..471
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-789 VKSLLFSHNHHLLSVQGCEAGLDVLAFEGDEALSQPFRYRIEFTSADHAISKEMMLMKAASLTLQAPVAQGFGINVQQPVRVIQGVVTGFERLGTSRDETHYALTLQPRLALLNRSHQNAIYQDQSVPQIVEKILRERHGLRGQDFLFSLTKTYPRREQVMQYGEDDLRFITRLLGEVGIWFRFTADTRLHIDVAEFCDSQQGYEKGLTLPSVPPSGQQSAGVDAVWEMACRHRVVEQQVSTRDYNYREATADMNAQVDVTRGETTTFGEAYHWGDNYLTAGNVHDRHPAPESGAFYARLRHERYLNGQTRMQATTSCPTLCPGQVLKVTGGEEVAREFADGVLITAMHSHARRDADFAVEFAGIPDSPDVGYRPEPGARPVMAGTLPARVTSTRENDTYGHIDKHGRYRVNMLFDRARWETGFESLWVRQSRPYAGDTYGLHLPLLAGTEVAIGFEDGNPDRPYIAGVLHDSAHGDHVTIRNDKRNVLRTPANNKIRLDDERGKEHIKVSTEYGGKSQLNLGHLVDSDRQPRGEGFELRTDSWGAIRAQKGIFISADGQVQAQGQVLAMEPAVSLLKGAVNQVTEWGSITQTHHNVIPDTGPLSALTTGASDLKQPTLLMSAPQGIAAVTPETTLLHSGKGLYLQSLGEVNITTAQRCSLNASQAISLLAQQEGMRLVSAKGPLQVESHGDILSLTALKDITVQSTQGHLQLTAKNGITLGCGGAYIRLTPQGEIQIHGPGVISLKGQHDLQGPVSEEFPLPELPASVCKECLKKAQALAQGFVPREA


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.7557 - -


  Protein sequence: 790 a.a.    

>T6CP005802 NC_016845:2335474-2337843 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssI]
VKSLLFSHNHHLLSVQGCEAGLDVLAFEGDEALSQPFRYRIEFTSADHAISKEMMLMKAASLTLQAPVAQGFGINVQQPV
RVIQGVVTGFERLGTSRDETHYALTLQPRLALLNRSHQNAIYQDQSVPQIVEKILRERHGLRGQDFLFSLTKTYPRREQV
MQYGEDDLRFITRLLGEVGIWFRFTADTRLHIDVAEFCDSQQGYEKGLTLPSVPPSGQQSAGVDAVWEMACRHRVVEQQV
STRDYNYREATADMNAQVDVTRGETTTFGEAYHWGDNYLTAGNVHDRHPAPESGAFYARLRHERYLNGQTRMQATTSCPT
LCPGQVLKVTGGEEVAREFADGVLITAMHSHARRDADFAVEFAGIPDSPDVGYRPEPGARPVMAGTLPARVTSTRENDTY
GHIDKHGRYRVNMLFDRARWETGFESLWVRQSRPYAGDTYGLHLPLLAGTEVAIGFEDGNPDRPYIAGVLHDSAHGDHVT
IRNDKRNVLRTPANNKIRLDDERGKEHIKVSTEYGGKSQLNLGHLVDSDRQPRGEGFELRTDSWGAIRAQKGIFISADGQ
VQAQGQVLAMEPAVSLLKGAVNQVTEWGSITQTHHNVIPDTGPLSALTTGASDLKQPTLLMSAPQGIAAVTPETTLLHSG
KGLYLQSLGEVNITTAQRCSLNASQAISLLAQQEGMRLVSAKGPLQVESHGDILSLTALKDITVQSTQGHLQLTAKNGIT
LGCGGAYIRLTPQGEIQIHGPGVISLKGQHDLQGPVSEEFPLPELPASVCKECLKKAQALAQGFVPREA*

  Nucleotide sequence: 2370 bp    

>T6CP005802 NC_016845:2335474-2337843 [Klebsiella pneumoniae subsp. pneumoniae HS11286] [TssI]
GTGAAATCGTTGTTGTTCAGCCATAACCACCACCTGCTTTCGGTGCAGGGATGTGAAGCCGGGCTTGATGTGCTGGCCTT
CGAGGGCGATGAAGCCCTGAGCCAGCCGTTCCGCTACCGTATTGAATTCACCAGCGCAGACCATGCCATCAGCAAAGAGA
TGATGCTGATGAAGGCAGCCTCCCTGACGCTGCAGGCGCCGGTGGCTCAGGGCTTCGGCATCAATGTTCAGCAACCCGTG
CGGGTGATCCAGGGCGTGGTGACGGGGTTTGAAAGGCTCGGTACCTCCAGGGATGAAACGCACTACGCGCTGACGCTTCA
GCCGCGCCTGGCGCTGCTCAACCGCTCGCACCAGAACGCCATTTACCAGGACCAGTCCGTTCCGCAGATTGTGGAAAAAA
TCCTCCGCGAGCGCCACGGCCTGCGCGGTCAGGATTTTCTGTTCTCGCTGACAAAAACGTATCCGCGACGCGAGCAGGTG
ATGCAGTACGGCGAGGATGACCTGCGCTTTATCACCCGGCTGCTGGGAGAGGTGGGGATCTGGTTTCGCTTTACCGCCGA
CACGCGGCTGCACATCGACGTCGCTGAGTTCTGCGACAGTCAGCAGGGCTATGAGAAGGGGCTGACGTTGCCTTCGGTCC
CGCCGTCAGGGCAGCAGTCGGCCGGGGTGGACGCGGTGTGGGAGATGGCATGCCGCCACCGCGTCGTGGAGCAGCAGGTC
AGTACCCGCGACTACAACTACCGCGAGGCGACGGCGGACATGAACGCGCAGGTGGATGTCACCCGCGGGGAGACCACCAC
CTTTGGTGAGGCTTACCACTGGGGAGATAACTACCTGACCGCCGGGAATGTCCATGACCGCCATCCGGCGCCGGAGTCCG
GGGCGTTTTACGCCCGTCTTCGTCATGAGCGTTATCTGAACGGCCAGACCCGGATGCAGGCCACCACCAGCTGCCCGACG
CTCTGCCCGGGACAGGTGCTGAAGGTCACCGGCGGAGAGGAGGTGGCCAGGGAGTTTGCTGATGGCGTGCTCATCACGGC
GATGCACAGCCACGCCCGGCGCGATGCCGACTTTGCGGTGGAGTTTGCCGGCATACCGGACAGCCCGGACGTCGGCTACC
GGCCTGAGCCCGGCGCGCGTCCGGTGATGGCCGGGACGCTGCCGGCCCGCGTGACCAGCACCCGGGAAAACGACACCTAC
GGGCATATCGACAAACACGGACGCTACCGGGTGAATATGTTGTTTGATCGGGCGCGCTGGGAAACCGGGTTCGAGAGCCT
GTGGGTCCGTCAGTCGCGGCCGTATGCCGGAGACACCTACGGCCTGCACCTGCCGCTGCTGGCCGGGACGGAGGTGGCGA
TTGGCTTTGAGGATGGTAACCCTGACCGGCCGTATATCGCGGGCGTGCTGCACGACTCGGCGCACGGCGACCACGTCACC
ATCCGCAATGACAAACGTAACGTCCTGCGCACCCCGGCCAACAACAAAATCCGCCTCGACGATGAGCGCGGGAAAGAACA
TATCAAGGTCAGCACGGAGTACGGCGGTAAAAGCCAGCTGAACCTGGGGCACCTGGTGGACAGTGACAGGCAGCCGCGCG
GCGAAGGCTTTGAGCTGAGAACCGACAGCTGGGGAGCTATCCGGGCACAGAAAGGGATATTTATCAGCGCGGACGGACAG
GTGCAGGCTCAGGGGCAGGTGCTGGCGATGGAGCCGGCGGTCAGTTTGCTGAAAGGTGCGGTGAATCAGGTCACGGAATG
GGGAAGCATTACGCAAACCCATCATAATGTTATCCCAGACACCGGCCCATTAAGCGCACTGACCACAGGCGCCAGCGATC
TTAAACAGCCGACATTGCTGATGTCGGCCCCGCAGGGGATTGCCGCAGTCACGCCGGAAACAACCCTCCTGCACAGCGGT
AAGGGGCTGTATCTGCAGAGCCTGGGAGAGGTCAACATCACCACGGCACAGCGCTGTTCTCTGAATGCCAGCCAGGCTAT
TTCACTGCTGGCGCAACAGGAGGGGATGAGGCTGGTCTCCGCCAAAGGTCCGCTGCAAGTAGAGTCGCACGGCGATATTC
TATCGCTGACCGCGCTAAAAGATATCACCGTCCAGTCAACCCAGGGGCATCTGCAGTTGACGGCTAAAAATGGCATCACC
CTGGGTTGCGGCGGCGCATATATCCGTCTTACCCCGCAGGGAGAGATACAGATCCACGGACCGGGGGTGATTAGCCTTAA
GGGGCAGCATGATTTGCAGGGGCCGGTCAGCGAGGAGTTTCCCTTGCCTGAGCTACCGGCATCGGTGTGTAAAGAGTGCC
TTAAAAAAGCCCAGGCGCTGGCGCAGGGCTTCGTGCCGCGGGAGGCATAG